Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Erik, Walinda"'
Publikováno v:
ACS Omega, Vol 7, Iss 4, Pp 3212-3221 (2022)
Externí odkaz:
https://doaj.org/article/efd1c6a456a9488e9b433677776f7c10
Autor:
Hiroaki Fujita, Akira Tokunaga, Satoshi Shimizu, Amanda L. Whiting, Francisco Aguilar-Alonso, Kenji Takagi, Erik Walinda, Yoshiteru Sasaki, Taketo Shimokawa, Tsunehiro Mizushima, Izuru Ohki, Mariko Ariyoshi, Hidehito Tochio, Federico Bernal, Masahiro Shirakawa, Kazuhiro Iwai
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1192-1204 (2018)
Summary: The linear ubiquitin chain assembly complex (LUBAC) participates in inflammatory and oncogenic signaling by conjugating linear ubiquitin chains to target proteins. LUBAC consists of the catalytic HOIP subunit and two accessory subunits, HOIL
Externí odkaz:
https://doaj.org/article/7c862e83f5e5418699f786a096c66df4
Publikováno v:
Current Protocols. 2
Cryogenic-probe-based Rheo-NMR spectroscopy is a recently developed methodology to obtain solution NMR spectra of protein samples in situ under external shear. It is applicable to atomic-resolution monitoring of protein aggregation in situ, thereby a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7b8315d059e1677ceb6ad5815e831c
https://doi.org/10.1002/cpz1.617
https://doi.org/10.1002/cpz1.617
Autor:
Erik Walinda1 walinda.erik.6e@kyoto-u.ac.jp, Kenji Sugase2,3, Naoki Ishii2, Masahiro Shirakawa2, Kazuhiro Iwai1, Daichi Morimoto2 morimoto@moleng.kyoto-u.ac.jp
Publikováno v:
Journal of Biological Chemistry. Sep2023, Vol. 299 Issue 9, p1-15. 15p.
Autor:
Daichi Morimoto, Erik Walinda, Yutaka Mahana, Masanori Osugi, Masahiro Shirakawa, Kenji Sugase
Publikováno v:
Biomolecular NMR Assignments. 15:427-431
von Willebrand factor (vWF) is an adhesive plasma protein that is important for platelet adhesion in normal hemostasis in response to vascular injury. Although large vWF multimers are released from storage granules of platelets and (sub-)endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5bc77aaa44a6992046d14e42bc0437
https://doi.org/10.1007/s12104-021-10041-8
https://doi.org/10.1007/s12104-021-10041-8
Publikováno v:
Biochemical and Biophysical Research Communications. 660:100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e47a691ec02a1eaa465c14425ad941ac
https://doi.org/10.1016/j.bbrc.2023.04.007
https://doi.org/10.1016/j.bbrc.2023.04.007
Autor:
Kenji Sugase, Masahiro Shirakawa, Daichi Morimoto, Erik Walinda, Sarah Leeb, Jens Danielsson, Naoto Iwakawa
Publikováno v:
The Journal of Physical Chemistry B. 125:2521-2532
Aggregate formation of superoxide dismutase 1 (SOD1) inside motor neurons is known as a major factor in onset of amyotrophic lateral sclerosis. The thermodynamic stability of the SOD1 β-barrel has been shown to decrease in crowded environments such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c2d0f2cf8505f2c9298a17a3ff4028
https://doi.org/10.1021/acs.jpcb.0c11162
https://doi.org/10.1021/acs.jpcb.0c11162
Autor:
Shingo Takashima, Daichi Morimoto, Erik Walinda, Kazuhiro Iwai, Kenji Sugase, Masahiro Shirakawa, Mayu Nishizawa
Publikováno v:
Biochemistry. 60:573-583
Polyubiquitin is a multifunctional protein tag formed by the covalent conjugation of ubiquitin molecules. Due to the high rigidity of the ubiquitin fold, the ubiquitin moieties in a polyubiquitin chain appear to be structurally equivalent to each oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2761e7036e40d67aca991e735b993281
https://doi.org/10.1021/acs.biochem.0c00619
https://doi.org/10.1021/acs.biochem.0c00619
Publikováno v:
Physical Chemistry Chemical Physics. 23:21484-21488
Drugs are designed and validated based on physicochemical data on their interactions with target proteins. For low water-solubility drugs, however, quantitative analysis is practically impossible without accurate estimation of precipitation. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600af2495194ce0c8371e8639c06f75c
https://doi.org/10.1039/d1cp03175a
https://doi.org/10.1039/d1cp03175a
Publikováno v:
Biochemical and Biophysical Research Communications. 529:418-424
Ubiquitination is one of the major post-translational modifications and entails conjugation of ubiquitin molecules to target proteins. To make free ubiquitin molecules available for conjugation, in cells ubiquitin is not only synthesized de novo, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0b571e0cd4a6b049403caca5135392
https://doi.org/10.1016/j.bbrc.2020.06.008
https://doi.org/10.1016/j.bbrc.2020.06.008