Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Erik, Springer"'
Publikováno v:
Endocrine Connections, Vol 7, Iss 1, Pp 47-55 (2017)
Poorly differentiated thyroid carcinoma (PDTC) is a rare malignancy with higher mortality than well-differentiated thyroid carcinoma. The histological diagnosis can be difficult as well as the therapy. Improved diagnosis and new targeted therapies re
Externí odkaz:
https://doaj.org/article/8899b1ae495d4406ab81b76df394dc5f
Autor:
Martina Ferrata, Arno Schad, Stefanie Zimmer, Thomas J. Musholt, Katharina Bahr, Julian Kuenzel, Sven Becker, Erik Springer, Wilfried Roth, Matthias M. Weber, Christian Fottner
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The potential of neuroendocrine neoplasms (NEN) to respond to checkpoint inhibitors is largely unknown and full of great expectations. Immunohistochemical (IHC) studies of programmed cell death ligand 1 (PD-L1) expression in the tumor microenvironmen
Externí odkaz:
https://doaj.org/article/c1d0700d969c42d1a5de48438618a00c
Autor:
Julia I Staubitz, Celine Müller, Antonia Heymans, Christina Merten, Bianca Roos, Alicia Poplawski, Annekathrin Ludt, Stephanie Strobl, Erik Springer, Arno Schad, Wilfried Roth, Thomas J Musholt, Nils Hartmann
Publikováno v:
BJS Open. 7
Background Currently, treatment recommendations for papillary thyroid carcinoma are not based on the genetic background causing tumourigenesis. The aim of the present study was to correlate the mutational profile of papillary thyroid carcinoma with c
Publikováno v:
Cellular Oncology, Vol 32, Iss 1-2, Pp 121-130 (2010)
Background: The general transcription factor II H (TFIIH), comprised of a core complex and an associated CAK-complex, functions in transcription, DNA repair and cell cycle control. Mutations of the two largest subunits, p89 (XPB) and p80 (XPD), cause
Externí odkaz:
https://doaj.org/article/61eb35dfbc3b412eabdca9ab355725ba
Autor:
Arno Schad, Wilfried Roth, Julia I. Staubitz, Thomas J. Musholt, Hauke Lang, N Hartmann, Erik Springer, Krishnaraj Rajalingam
Publikováno v:
Cancer Genetics. 238:10-17
Background Rearrangements of RET are drivers of oncogenesis, traceable in different cancer types as papillary thyroid carcinoma (PTC), non-small cell lung cancer, colorectal or breast cancer. Anchored multiplex PCR based next-generation sequencing (N
Autor:
Beate K. Straub, Diane Duret, Erik Springer, Wilfried Roth, Sebastian Schotten, Marcus A. Wörns, Dirk A. Ridder, Michael Kloth, Stefan Heinrich
Publikováno v:
Zeitschrift für Gastroenterologie. 57:46-51
ZusammenfassungMutationen des hepatocyte nuclear factor 1 α-(HNF1α) Gens lösen einen MODY3-Diabetes aus und sind mit einer hepatozellulären Adenomatose assoziiert. Eine maligne Transformation von HNF1α-mutierten hepatozellulären Adenomen ist se
Autor:
Wilfried Roth, Martina Ferrata, Stefanie Zimmer, Thomas J. Musholt, Katharina Bahr, Matthias M. Weber, Arno Schad, Christian Fottner, Sven Becker, Julian Kuenzel, Erik Springer
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
The potential of neuroendocrine neoplasms (NEN) to respond to checkpoint inhibitors is largely unknown and full of great expectations. Immunohistochemical (IHC) studies of programmed cell death ligand 1 (PD-L1) expression in the tumor microenvironmen
Autor:
Dirk Andreas, Ridder, Diane, Duret, Marcus-Alexander, Wörns, Sebastian, Schotten, Stefan, Heinrich, Michael, Kloth, Erik, Springer, Wilfried, Roth, Beate Katharina, Straub
Publikováno v:
Zeitschrift fur Gastroenterologie. 57(1)
Hepatocyte nuclear factor 1 α (HNF1α) mutations cause maturity-onset diabetes of the young (MODY) type 3 and are associated with hepatocellular adenomatosis. Malignant transformation of HNF1α-mutated hepatocellular adenomas is rare. We report a ca
Autor:
Erik Springer, Christoph Matthias, Benjamin Philipp Ernst, Katharina Bahr, Christian Fottner, Sven Becker, Julian Künzel, Stefanie Zimmer
Publikováno v:
ORL; journal for oto-rhino-laryngology and its related specialties. 81(5-6)
Background: Human papillomavirus (HPV)-related head and neck squamous cell carcinoma represents an important subgroup of head and neck cancer, but HPV occurs also in the less common neuroendocrine carcinomas (NEC). The PD-1/PD-L1 pathway appears to b
Autor:
Sonja Thaler, Charles James Kirkpatrick, Erik Springer, Arno Schad, Marcus Schmidt, Jonathan P. Sleeman, Cristina Cotarelo
Publikováno v:
Oncotarget
// Cristina L. Cotarelo 1 , Arno Schad 1 , Charles James Kirkpatrick 1 , Jonathan P. Sleeman 2, 3 , Erik Springer 1 , Marcus Schmidt 4 , Sonja Thaler 2 1 Institute of Pathology, University Medical Center, Johannes Gutenberg University, Mainz, Germany