Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Erik, Rollman"'
Autor:
Robert De Rose, Caroline S Fernandez, Miranda Z Smith, C Jane Batten, Sheilajen Alcântara, Vivienne Peut, Erik Rollman, Liyen Loh, Rosemarie D Mason, Kim Wilson, Matthew G Law, Amanda J Handley, Stephen J Kent
Publikováno v:
PLoS Pathogens, Vol 4, Iss 5, p e1000055 (2008)
Effective immunotherapies for HIV are needed. Drug therapies are life-long with significant toxicities. Dendritic-cell based immunotherapy approaches are promising but impractical for widespread use. A simple immunotherapy, reinfusing fresh autologou
Externí odkaz:
https://doaj.org/article/26fb892835a04cc79c0cebdf0ebb140f
Autor:
Martin Ingelsson, Hans Basun, Christer Möller, Lars Lannfelt, Irina Alafuzoff, Lars Hillered, Sami Abu Hamdeh, Niklas Marklund, Erik Rollman Waara, Linda Söderberg
Publikováno v:
Brain Pathology. 28:451-462
Deposition of amyloid-β (Aβ) is central to Alzheimer's disease (AD) pathogenesis and associated with progressive neurodegeneration in traumatic brain injury (TBI). We analyzed predisposing factors ...
Autor:
Sami, Abu Hamdeh, Erik Rollman, Waara, Christer, Möller, Linda, Söderberg, Hans, Basun, Irina, Alafuzoff, Lars, Hillered, Lars, Lannfelt, Martin, Ingelsson, Niklas, Marklund
Publikováno v:
Brain pathology (Zurich, Switzerland). 28(4)
Deposition of amyloid-β (Aβ) is central to Alzheimer's disease (AD) pathogenesis and associated with progressive neurodegeneration in traumatic brain injury (TBI). We analyzed predisposing factors for Aβ deposition including monomeric Aβ40, Aβ42
Akademický článek
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Publikováno v:
The Journal of Immunology. 182:1202-1210
Ab-dependent cellular cytotoxicity (ADCC) Abs stimulate NK cell effector functions and play a role in protecting from and controlling viral infections. We characterized ADCC Abs in a cross-sectional cohort of 80 HIV-infected subjects not on antiretro
Autor:
Andreas Suhrbier, Erik Rollman, Vlad Mokhonov, Viv Peut, Xiang Ju Wang, Ekaterina I. Mokhonova, Alexander A. Khromykh, Sheilajen Alcantara, Caroline S. Fernandez, Kim Wilson, Liyen Loh, Rosemarie D. Mason, Robert De Rose, Stephen J. Kent, Jeanette C. Reece
Publikováno v:
Virology. 374:528-534
Persistent gag-specific T cell immunity would be a useful component of an effective HIV vaccine. The Flavivirus Kunjin replicon was previously engineered to persistently express HIV gag and was shown to induce protective responses in mice. We evaluat
Autor:
Erik Rollman, Damian F. J. Purcell, Andrew G. Brooks, Ian A. Ramshaw, Bartek Zuber, Stephen J. Kent, Miranda Zoe Denham Smith
Publikováno v:
The Journal of Immunology. 179:4571-4579
Both the magnitude and function of vaccine-induced HIV-specific CD8+ CTLs are likely to be important in the outcome of infection. We hypothesized that rapid cytolysis by CTLs may facilitate control of viral challenge. Release kinetics of the cytolyti
Autor:
Erik Rollman, Mauro Magnani, Jorma Hinkula, Barbara Ensoli, Susan W. Barnett, Indresh K. Srivastava, Lars E. Eriksson, Andreas Bråve, Aurelio Cafaro, Britta Wahren
Publikováno v:
Vaccine. 25:6882-6890
Pre-clinical HIV-1 vaccine protocols, using multiple vaccine modalities and a potent adjuvant were assessed for vaccine efficacy in an experimental HIV-1 challenge model. C57Bl/6 mice were immunized with DNA plasmids encoding HIV-1 gp140, Gag and Tat
Autor:
Andreas Boberg, Andreas Bråve, Erik Rollman, Anne Kjerrström, Kajsa Aperia, Reinhold Benthin, Gunnel Engström, Susanne Johansson, Nathalie Louise Mathy, Jorma Hinkula, Jonathan L. Heeney, Cathy van Wely, Peter Franz Ertl, Lars E. Eriksson, Britta Wahren, Gerald Voss
Publikováno v:
Vaccine. 25:2145-2154
A DNA plasmid encoding human immunodeficiency virus type 1 (HIV-1) env, nef and tat genes was used in mice in a prime-boost immunization regimen with the corresponding recombinant proteins. The genetic immunogen was delivered with a gene gun and the
Autor:
Pontus Blomberg, Björn Lundgren, Karl Ljungberg, Andreas Bråve, Erik Rollman, Andreas Boberg, Jorma Hinkula, Maria G. Isaguliants, Britta Wahren
Publikováno v:
Molecular Therapy. 12:1197-1205
Gene vaccination encounters problems different from those of gene therapy since both a short half-life of the gene and a strong immune response to the gene product are desirable. We have evaluated a DNA vaccine consisting of seven plasmids encoding n