Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Erik, Lubberts"'
Autor:
Sara Parsa, Zahra-Soheila Soheili, Hamidreza Alizadeh Otaghvar, Elham Behrangi, Parvin Mansouri, Erik Lubberts, Seyed Javad Mowla
Publikováno v:
Cell Journal, Vol 25, Iss 5, Pp 300-306 (2023)
Objective: Psoriasis is a common, auto-immune skin disease characterized by abnormal proliferation and differentiationof keratinocytes. Studies revealed the role of stress stimulators in the pathogenesis of psoriasis. Oxidative stressand heat shock a
Externí odkaz:
https://doaj.org/article/697450cc49d34a738c2e256dd56af2d6
Autor:
Hannah den Braanker, Wida Razawy, Kim Wervers, Anne-Marie C. Mus, Nadine Davelaar, Marc R. Kok, Erik Lubberts
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Abstract Background Psoriasis patients developing psoriatic arthritis (PsA) are thought to go through different phases. Understanding the underlying events in these phases is crucial to diagnose PsA early. Here, we have characterized the circulating
Externí odkaz:
https://doaj.org/article/b5b109e680964125814cb04fe51be791
Autor:
Sita M A Bierma-Zeinstra, Edwin H G Oei, Robert-Jan de Vos, Maryam Kavousi, Erik Lubberts, Dieuwke Schiphof, Joyce B J van Meurs, P Koen Bos, Eveline Molendijk, M Carola Zillikens, Bram C J van der Eerden, Boris W V Schouten, Mariëlla I B de Rooij-Duran
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction The incidence of degenerative disorders, including osteoarthritis (OA), increases rapidly in women after menopause. However, the influence of the menopause is still insufficiently investigated due to the slowness of menopausal transition
Externí odkaz:
https://doaj.org/article/c972447fe56949c29d0f486f245a6444
Autor:
Wendy Dankers, Hannah den Braanker, Sandra M. J. Paulissen, Jan Piet van Hamburg, Nadine Davelaar, Edgar M. Colin, Erik Lubberts
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Chronic synovial inflammation is an important hallmark of inflammatory arthritis, but the cells and mechanisms involved are incompletely understood. Previously, we have shown that CCR6+ memory T-helper (memTh) cells and synovial f
Externí odkaz:
https://doaj.org/article/526263f0e7cc4401a91b7282c617800f
Autor:
Wida Razawy, Celso H. Alves, Marijke Koedam, Patrick S. Asmawidjaja, Adriana M. C. Mus, Mohamed Oukka, Pieter J. M. Leenen, Jenny A. Visser, Bram C. J. van der Eerden, Erik Lubberts
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate these processes via different pathways. However, the potential role of this pathwa
Externí odkaz:
https://doaj.org/article/4178bd5619304f8498fcb69ed29bb6bc
Autor:
Steven C. Koetzier, Jamie van Langelaar, Annet F. Wierenga-Wolf, Marie-José Melief, Kim Pol, Suzanne Musters, Erik Lubberts, Willem A. Dik, Joost Smolders, Marvin M. van Luijn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In early multiple sclerosis (MS), an IFN-γhighGM-CSFhighIL-17low CD4+ T-cell subset termed T helper 17.1 (Th17.1) reveals enhanced capacity to infiltrate the central nervous system. Th17.1 cells express high levels of multidrug resistance protein 1
Externí odkaz:
https://doaj.org/article/28c97a48d5f44f019256739f1b535070
Autor:
Radjesh Bisoendial, Erik Lubberts
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Interleukin 17A (IL-17A) has been put forward as a strong ally in our fight against invading pathogens across exposed epithelial surfaces by serving an antimicrobial immunosurveillance role in these tissues to protect the barrier integrity. Amongst o
Externí odkaz:
https://doaj.org/article/a0df15209c944bc38acd75acefbb71c8
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Spectral flow cytometry is an upcoming technique that allows for extensive multicolor panels, enabling simultaneous investigation of a large number of cellular parameters in a single experiment. To fully explore the resulting high-dimensional single
Externí odkaz:
https://doaj.org/article/329e841f3f30488188d05aba33aeed9e
Autor:
Xiaofei Xu, Errol Prens, Edwin Florencia, Pieter Leenen, Luis Boon, Patrick Asmawidjaja, Anne-Marie Mus, Erik Lubberts
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IL-17A has been shown to be up-regulated in psoriasis lesions and is central to psoriasis pathogenesis. IL-19, along with other IL-20 subfamily cytokines such as IL-20 and IL-24, is induced by IL-17A and contributes especially to epidermal hyperplasi
Externí odkaz:
https://doaj.org/article/39816b5c3df24cb291f16351ba059bf8
Epigenome wide association study of response to methotrexate in early rheumatoid arthritis patients.
Autor:
Helen R Gosselt, Costanza L Vallerga, Pooja R Mandaviya, Erik Lubberts, Johanna M W Hazes, Robert de Jonge, Sandra G Heil
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247709 (2021)
AimTo identify differentially methylated positions (DMPs) and regions (DMRs) that predict response to Methotrexate (MTX) in early rheumatoid arthritis (RA) patients.Materials and methodsDNA from baseline peripheral blood mononuclear cells was extract
Externí odkaz:
https://doaj.org/article/736434ab899447cabb519e42f9e12903