Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Erik, Kwidzinski"'
Autor:
Lena Smirnova, Stefan Schumacher, Agnieszka Rybak, Erik Kwidzinski, F. Gregory Wulczyn, Olaf Ninnemann, Robert Nitsch, Andrea Seiler, Christine Brandt, Michael Strehle
Publikováno v:
The FASEB Journal. 21:415-426
The let-7 miRNA regulates developmental timing in C. elegans and is an important paradigm for investigations of miRNA functions in mammalian development. We have examined the role of miRNA precursor processing in the temporal control and lineage spec
Autor:
Jacqueline Mahlo, Ingo Bechmann, Daniel Richter, Erik Kwidzinski, Jana Goldmann, Christine Brandt
Publikováno v:
Journal of Leukocyte Biology. 80:797-801
Although drainage pathways of soluble antigens from brain to cervical lymph nodes have been well established, there is no direct evidence for similar routes of leukocytes leaving the central nervous system. We developed a protocol allowing the cross-
Autor:
Ingo Bechmann, Frederick Naftolin, Adam D. Kovac, Josef Priller, Ulrich Dirnagl, Erik Kwidzinski, Robert Nitsch, Eva Simbürger, Jana Goldmann
Publikováno v:
The FASEB Journal. 19:1-19
In this study, we demonstrate the infiltration of blood-derived monocytic cells and their morphologic transformation into microglia in zones of acute, anterograde (Wallerian) axonal degeneration induced by entorhinal cortex lesion (ECL). ECL was perf
Autor:
Robert Nitsch, Erik Kwidzinski, Barbara Steiner, Susanne A. Wolf, Ingo Bechmann, Jasmin Fisher
Publikováno v:
Journal of Neuroimmunology. 133:72-80
This study analyzes how the antigen specificity, the subtype, and the activation state of T cells modulate their recently discovered neuroprotective potential. We assessed the prevention from neuronal damage in organotypic entorhinal-hippocampal slic
Autor:
Erik Kwidzinski, Ulrike Gimsa, Josef Priller, Tamas L. Horvath, Adam D. Kovac, Robert Nitsch, Ulrich Dirnagl, Eva Simbürger, Ingo Bechmann
Publikováno v:
Experimental Neurology. 168:242-249
Brain perivascular spaces harbor a population of cells which exhibit high phagocytic capacity. Therefore, these cells can be labeled by intraventricular injection of tracers. Such perivascular cells at the interface between blood and brain are believ
Publikováno v:
Neuroscience letters. 425(3)
Fibre tract injury evokes recruitment of antigen-presenting- and T cells, but does not cause autoimmune demyelination. This implies that immune tolerance to myelin is actively maintained or readily re-established. Using entorhinal cortex lesion (ECL)
Autor:
Erik Kwidzinski, Ingo Bechmann
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 85(12)
The tryptophan-catabolizing enzyme indoleamine-2,3-dioxygenase (IDO) initiates the first and rate-limiting step of the kynurenine pathway. It is induced by proinflammatory cytokines such as interferon-beta and interferon-gamma and has established eff
Autor:
Ulrike Gimsa, Orhan Aktas, Robert Nitsch, Erik Kwidzinski, Ingo Bechmann, Jacqueline Mahlo, Christine Brandt, Birgit Sawitzki, Leman Mutlu, Marloes van Zwam, Jon D. Laman
Publikováno v:
Experimental Brain Research, 178(4), 542-553. Springer-Verlag
Despite transient, myelin-directed adaptive immune responses in regions of fiber tract degeneration, none of the current models of fiber tract injuries evokes disseminated demyelination, implying effective mechanisms maintaining or re-establishing im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ab67cc99d2dd0eabb711dc705ef2d5
https://pure.eur.nl/en/publications/8c668461-4fe6-40dc-81e2-f5317aea0e2c
https://pure.eur.nl/en/publications/8c668461-4fe6-40dc-81e2-f5317aea0e2c
Autor:
F Gregory, Wulczyn, Lena, Smirnova, Agnieszka, Rybak, Christine, Brandt, Erik, Kwidzinski, Olaf, Ninnemann, Michael, Strehle, Andrea, Seiler, Stefan, Schumacher, Robert, Nitsch
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(2)
The let-7 miRNA regulates developmental timing in C. elegans and is an important paradigm for investigations of miRNA functions in mammalian development. We have examined the role of miRNA precursor processing in the temporal control and lineage spec
Autor:
Daniel Richter, Erik Kwidzinski, Robert Nitsch, Ingo Bechmann, Leman Mutlu, Frauke Zipp, Jörg Bunse, Orhan Aktas
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(10)
The tryptophan (trp)-catabolizing enzyme indolamine 2,3-dioxygenase (IDO) is induced by the T helper 1 (Th 1) cytokine IFN-gamma during infections in various tissues including the brain. Recent studies demonstrated an immune modulatory function of th