Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Ericka Nevarez"'
1
Akademický článek
Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists
Autor: Shristi Pawnikar, Brenda S Magenheimer, Keya Joshi, Ericka Nevarez-Munoz, Allan Haldane, Robin L Maser, Yinglong Miao
Publikováno v: eLife, Vol 13 (2024)
Polycystin-1 (PC1) is the protein product of the PKD1 gene whose mutation causes autosomal dominant Polycystic Kidney Disease (ADPKD). PC1 is an atypical G protein-coupled receptor (GPCR) with an autocatalytic GAIN domain that cleaves PC1 into extrac
Externí odkaz: https://doaj.org/article/4f77a5a022894bf284cd5a67536e884c
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2
Akademický článek
Mechanism of tethered agonist-mediated signaling by polycystin-1
Autor: Pawnikar, Shristi, Magenheimer, Brenda S., Munoz, Ericka Nevarez, Mase, Robin L., Miao, Yinglong
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2022 May 01. 119(19), 1-10.
Externí odkaz: https://www.jstor.org/stable/27151613
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3
Constitutive signaling by the C-terminal fragment of polycystin-1 is mediated by a tethered peptide agonist
Autor: Ericka Nevarez Munoz, Robin L. Maser, Jayalakshmi Ravichandran, Brenda S. Magenheimer
Mutation of the PKD1 gene, encoding polycystin-1 (PC1), is the primary cause of autosomal dominant polycystic kidney disease. PC1 is an 11-transmembrane domain protein that binds and modulates the activity of multiple heterotrimeric G protein familie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a95daabf8ab041c0942a45d7d25bc935
https://doi.org/10.1101/2021.08.20.457171
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8
Akademický článek
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Akademický článek
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10
Akademický článek
Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists.
Autor: Pawnikar S; Center for Computational Biology and Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66047., Magenheimer BS; Clinical Laboratory Sciences, University of Kansas Medical Center, Kansas City, KS 66160.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160., Joshi K; Department of Pharmacology and Computational Medicine Program, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599., Munoz EN; Clinical Laboratory Sciences, University of Kansas Medical Center, Kansas City, KS 66160., Haldane A; Dept of Physics, and Center for Biophysics and Computational Biology, Temple University, Philadelphia, PA 19122., Maser RL; Departments of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS 66160.; Clinical Laboratory Sciences, University of Kansas Medical Center, Kansas City, KS 66160.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160., Miao Y; Department of Pharmacology and Computational Medicine Program, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 10. Date of Electronic Publication: 2024 Jul 10.
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