A fine-tuned vector-parasite dialogue in tsetse's cardia determines peritrophic matrix integrity and trypanosome transmission success.

Autor: Aurélien Vigneron, Emre Aksoy, Brian L Weiss, Xiaoli Bing, Xin Zhao, Erick O Awuoche, Michelle B O'Neill, Yineng Wu, Geoffrey M Attardo, Serap Aksoy

Publikováno v: PLoS Pathogens, Vol 14, Iss 4, p e1006972 (2018)

Arthropod vectors have multiple physical and immunological barriers that impede the development and transmission of parasites to new vertebrate hosts. These barriers include the peritrophic matrix (PM), a chitinous barrier that separates the blood bo

Externí odkaz: https://doaj.org/article/0b6133f092124feb991288a2631936e6

Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda

Autor: James M. Njunge, Martin K. Rono, Bartholomew N. Ondigo, Catherine N. Mutuku, Erick O. Awuoche, Kariuki Ndung’u, Paul O. Mireji, Vincent O. Adung'a, Modesta O. Akoth, Rosemary Bateta, Clarence M. Mang’era

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss, Pp 57-67 (2021)
International Journal for Parasitology: Drugs and Drug Resistance

Human African Trypanosomiasis (HAT) is a disease of major economic importance in Sub-Saharan Africa. The HAT is caused by Trypanosoma brucei rhodesiense (Tbr) parasite in eastern and southern Africa, with suramin as drug of choice for treatment of ea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dc2c04531cf23242aeb8db944f32b4
http://www.sciencedirect.com/science/article/pii/S221132072100004X

Species-specific transcriptional profiles of the gut and gut microbiome of Ceratitis quilicii and Ceratitis rosa sensu stricto

Autor: Fathiya M. Khamis, Anna R. Malacrida, Fidelis L. O. Ombura, Erick O. Awuoche, Chrysantus M. Tanga, Martin K. Rono, Paul O. Mireji, Samira A. Mohamed, Sunday Ekesi

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)

The fruit fly species, Ceratitis rosa sensu stricto and Ceratitis quilicii, are sibling species restricted to the lowland and highland regions, respectively. Until recently, these sibling species were considered as allopatric populations of C. rosa w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933dc3452749d3fe0a9673b42fc86d51
https://pubmed.ncbi.nlm.nih.gov/31798006

Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda

Autor: Catherine N. Mutuku, Rosemary Bateta, Martin K. Rono, James M. Njunge, Erick O. Awuoche, Kariuki Ndung'u, Clarence M. Mang'era, Modesta O. Akoth, Vincent O. Adung'a, Bartholomew N. Ondigo, Paul O. Mireji

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance, Vol 15, Iss , Pp 57-67 (2021)

Human African Trypanosomiasis (HAT) is a disease of major economic importance in Sub-Saharan Africa. The HAT is caused by Trypanosoma brucei rhodesiense (Tbr) parasite in eastern and southern Africa, with suramin as drug of choice for treatment of ea

Externí odkaz: https://doaj.org/article/02d13e9ccdac4824b2638eb0864657d7

Expression profiling of Trypanosoma congolense genes during development in the tsetse fly vector Glossina morsitans morsitans

Autor: Erick O. Awuoche, Brian L. Weiss, Paul O. Mireji, Aurélien Vigneron, Benson Nyambega, Grace Murilla, Serap Aksoy

Publikováno v: Parasites & Vectors, Vol 11, Iss 1, Pp 1-18 (2018)

Abstract Background The tsetse transmitted parasitic flagellate Trypanosoma congolense causes animal African trypanosomosis (AAT) across sub-Saharan Africa. AAT negatively impacts agricultural, economic, nutritional and subsequently, health status of

Externí odkaz: https://doaj.org/article/4ff6b82289d24f88ac772214d322e1e3