FTD-associated behavioural and transcriptomic abnormalities in ‘humanized’ progranulin-deficient mice: A novel model for progranulin-associated FTD

Autor: Benjamin Life, Terri L. Petkau, Giuliano N.F. Cruz, Erick I. Navarro-Delgado, Ning Shen, Keegan Korthauer, Blair R. Leavitt

Publikováno v: Neurobiology of Disease, Vol 182, Iss , Pp 106138- (2023)

Frontotemporal dementia (FTD) is an early onset dementia characterized by neuropathology and behavioural changes. A common genetic cause of FTD is haploinsufficiency of the gene progranulin (GRN). Mouse models of progranulin deficiency have provided

Externí odkaz: https://doaj.org/article/14216bfcd001432dbedbf9abe076de7e

Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection

Autor: Aylin Del Moral-Morales, Ernesto Soto-Reyes, Jan Baumbach, Rodrigo González-Barrios, Erick I. Navarro-Delgado, Nicolas Alcaraz, Marisol Salgado-Albarrán

Publikováno v: NPJ Systems Biology and Applications
Salgado-Albarrán, M, Navarro-Delgado, E I, Del Moral-Morales, A, Alcaraz, N, Baumbach, J, González-Barrios, R & Soto-Reyes, E 2021, ' Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection ', npj Systems Biology and Applications, vol. 7, no. 1, 21 . https://doi.org/10.1038/s41540-021-00181-x
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-14 (2021)
Salgado-Albarrán, M, Navarro-Delgado, E I, Del Moral-Morales, A, Alcaraz, N, Baumbach, J, González-Barrios, R & Soto-Reyes, E 2021, ' Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection ', n p j Systems Biology and Applications, vol. 7, 21 . https://doi.org/10.1038/s41540-021-00181-x

COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in SARS-CoV-2 infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae8bdc1f5699af4dd42d30eece35c8f
http://europepmc.org/articles/PMC8144203

Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection.

Autor: Salgado-Albarrán, Marisol^1,2, Navarro-Delgado, Erick I.³, Del Moral-Morales, Aylin¹, Alcaraz, Nicolas⁴, Baumbach, Jan^5,6, González-Barrios, Rodrigo³ rodrigop@ciencias.unam.mx, Soto-Reyes, Ernesto¹ esotoreyes@cua.uam.mx

Publikováno v: NPJ Systems Biology & Applications. 5/24/2021, Vol. 7 Issue 1, p1-14. 14p.