Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Erich V. Scheller"'
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Bordetella filamentous hemagglutinin (FHA), a primary component of acellular pertussis vaccines, contributes to virulence, but how it functions mechanistically is unclear. FHA is first synthesized as an ~370-kDa preproprotein called FhaB. Re
Externí odkaz:
https://doaj.org/article/abdb820fc385442cb40926f0005786cc
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of experimental evidence supporting this conclusion for Bordetella pertussis and evidence against a requirement for FIM in adherence of Bordetella bron
Externí odkaz:
https://doaj.org/article/4f43bdadfb4c4501b0bdc75328f3a54b
Autor:
Kevin J. McHugh, Chen Chen, Benjamin Lee, Keven M. Robinson, Michelle E. Clay, John F. Alcorn, Richard I. Enelow, Sivanarayana Mandalapu, Patricia J. Dubin, Erich V. Scheller, Y. Peter Di
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L158-L167
Suppression of type 17 immunity by type I interferon (IFN) during influenza A infection has been shown to enhance susceptibility to secondary bacterial pneumonia. Although this mechanism has been described in coinfection with gram-positive bacteria,
Autor:
Aaron J. Wilk, Rebecca Anthouard, Steven M. Julio, M. Ashley Bone, Erich V. Scheller, Qing Chen, Peggy A. Cotter, Sara A. Marlatt, Andrew I. Perault, Scott Stibitz
Bacterial pathogens coordinate virulence using two-component regulatory systems (TCS). The Bordetella virulence gene (BvgAS) phosphorelay-type TCS controls expression of all known protein virulence factor-encoding genes and is considered the "master
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9e20c16f8093f4ec77879433f6cc4e
https://europepmc.org/articles/PMC5338435/
https://europepmc.org/articles/PMC5338435/
Autor:
M. Merle Elloso, Erich V. Scheller, Sivanarayana Mandalapu, Jay K. Kolls, John F. Alcorn, Sally E. Wenzel, Michelle L. Manni, John B. Trudeau
Publikováno v:
Mucosal immunology
Asthma is a common respiratory disease affecting approximately 300 million people worldwide. Airway inflammation is thought to contribute to asthma pathogenesis, but the direct relationship between inflammation and airway hyperresponsiveness remains
Publikováno v:
Molecular Microbiology. 90:716-733
Summary Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg+ phase is necessary and sufficient fo
Autor:
Cheryl L. Fattman, Jay K. Kolls, John F. Alcorn, Erich V. Scheller, Richard I. Enelow, Kevin J. McHugh, Derek Pociask, Sivanarayana Mandalapu
Publikováno v:
The American Journal of Pathology. 182(4):1286-1296
Influenza infection is widespread in the United States and the world. Despite low mortality rates due to infection, morbidity is common and little is known about the molecular events involved in recovery. Influenza infection results in persistent dis
Autor:
Erich V. Scheller, Samantha Slight, Anupa Kudva, Shabaana A. Khader, Jay K. Kolls, John F. Alcorn, Patricia J. Dubin, Keven M. Robinson, Chris R. Crowe, Richard I. Enelow, Sun Mi Choi
Publikováno v:
The Journal of Immunology. 186:1666-1674
Staphylococcus aureus is a significant cause of hospital and community acquired pneumonia and causes secondary infection after influenza A. Recently, patients with hyper-IgE syndrome, who often present with S. aureus infections of the lung and skin,
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
mBio
mBio
Bordetella filamentous hemagglutinin (FHA), a primary component of acellular pertussis vaccines, contributes to virulence, but how it functions mechanistically is unclear. FHA is first synthesized as an ~370-kDa preproprotein called FhaB. Removal of
Publikováno v:
mBio
mBio, Vol 6, Iss 3 (2015)
mBio, Vol 6, Iss 3 (2015)
Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of experimental evidence supporting this conclusion for Bordetella pertussis and evidence against a requirement for FIM in adherence of Bordetella bronchiseptic