Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Erich Schlick"'
Autor:
Vicente Guillem, Andres Poveda, Manuel Llombart, Erich Schlick, Ana Benavides, Cristóbal Gaspar, Miguel Martín, Virtudes Soriano, Miguel Muñoz, Amparo Ruiz, Ernesto Forner, Teresa Olmos, Carlos Fernández-Martos
Publikováno v:
Investigational New Drugs. 10:177-181
Mitonafide was the first synthetized compound of a new series of 3-nitronaphthalimides with intercalative properties. A phase I study with a conventional escalation scheme was developed. The schedule of drug administration was a daily x 5 days by sho
Autor:
Mostafa Nokta, Paul I. Nadler, Mark Jennings, Richard B. Pollard, Debbie S. Matzke, Erich Schlick
Publikováno v:
Experimental Biology and Medicine. 197:144-149
Tumor necrosis factor-alpha (TNF-alpha) has a spectrum of biologic effects and has been shown to exert antiviral effects in fibroblasts in vitro. The in vivo administration of TNF-alpha (40-160 micrograms/m2 intravenously over 2 hr) and its effects o
Autor:
Erich Schlick, Joachim Kempeni, Andreas Kist, Manfred Kaufmann, U. Räth, Jutta Hofmann, Burkhard Kommerell, Gunther Bastert, Bertram Wiedenmann, Hans Schmid, Daniela N. Männel
Publikováno v:
European Journal of Cancer and Clinical Oncology. 27:121-125
29 patients with refractory malignant ascites due to metastatic peritoneal spread of adenocarcinomas originating from the ovary, gastrointestinal tract, liver, breast and uterus were treated in a phase I trial of intraperitoneal infusions of recombin
Publikováno v:
Urologia internationalis. 47(3)
In experimental cell lines and in some human tumors, calcium antagonists reversed multidrug resistance mediated by P-170 glycoprotein in vitro. So far, clinical trials have not been very rewarding as intrinsic cardiovascular activities of these compo
Publikováno v:
Cytokine. 2(3)
Three stable murine hybridoma cell lines, which secrete monoclonal antibodies (mAb) to human tumor necrosis factor alpha (TNF alpha), were established. None of the monoclonal antibodies cross-reacted with lymphotoxin, interleukin 2 (IL 2) or Interfer
Autor:
Werner Hunstein, U. Räth, Bertram Wiedenmann, Erich Schlick, Peter Reichardt, Birgit Schüle, Joachim Kempeni, Anthony D. Ho, Burkhard Kommerell, Lorenz Theilmann
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 115:189-192
Fifteen patients with advanced metastatic adenocarcinomas were treated in a phase-I study with continuous intravenous 24 h infusion of recombinant tumor necrosis factor alpha (TNF-alpha) in order to determine the maximum tolerated dose (MTD) and asso
Publikováno v:
Journal of Immunopharmacology. 5:129-146
Prostaglandins of the E series (PGE), produced by mononuclear phagocytes, have many biological activities and are involved in the regulation of myelopoiesis and of the cytotoxic activities of macrophage (M phi) and natural killer (NK) cells. Since on
Publikováno v:
Cellular Immunology. 82:334-342
Human chorionic gonadotrophin preparations (hCG), when injected ip daily for 4 days, suppress the delayed-type hypersensitivity (DTH) response of mice to sheep red blood cells. Preparations of crude hCG, purified hCG subunits, and hCG that was formed
Autor:
Erich Schlick, Francis W. Ruscetti
Publikováno v:
Blood. 67:980-987
We have investigated the mechanisms by which colony-stimulating factor (CSF)-inducing biological response modifiers (BRM) may have beneficial effects on tumor-bearing hosts undergoing anti-tumor therapy. First, we have documented that treatment of mi