Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Erich Graf von Roedern"'
Autor:
Roland Haubner, Erich Graf von Roedern, Alfred Jonczyk, Armin Geyer, Beate Diefenbach, Simon Goodman, Horst Kessler, Dirk Finsinger, Gerhard Müller, Marion Gurrath, Jochen Wermuth, Günter Hölzemann
Publikováno v:
Letters in Peptide Science. 2:155-160
Integrins play a major role in cell-cell and cell-matrix interactions. The majority of the different types of integrins recognize the tripeptide sequence arginine-glycine-aspartic acid (RGD). To explore the spatial requirements of the pharmacophore f
Autor:
Horst Kessler, Erich Graf Von Roedern
Publikováno v:
Angewandte Chemie. 106:684-686
Publikováno v:
Biological chemistry. 378(12)
By exploiting the thiol function of L-cysteine as a chelating group of the active-site zinc atom of matrix metalloproteinases (MMPs), N- and C-terminal derivatization of this amino acid with aliphatic and aromatic groups allowed us to explore the sel