Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erich, Michel"'
Autor:
Stefano Cucuzza, Malgorzata Sitnik, Simon Jurt, Erich Michel, Wenzhao Dai, Thomas Müntener, Patrick Ernst, Daniel Häussinger, Andreas Plückthun, Oliver Zerbe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Ultra-tight binding is usually observed for proteins associating with rigidified molecules. Previously, we demonstrated that femtomolar binders derived from the Armadillo repeat proteins (ArmRPs) can be designed to interact very tightly with
Externí odkaz:
https://doaj.org/article/6ecd578ebede4e9a9fc2b3220ddf5f61
Autor:
Stefan Gerhardy, Michaela Oborská-Oplová, Ludovic Gillet, Richard Börner, Rob van Nues, Alexander Leitner, Erich Michel, Janusz J. Petkowski, Sander Granneman, Roland K. O. Sigel, Ruedi Aebersold, Vikram Govind Panse
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently
Externí odkaz:
https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94
Autor:
Oliver Zerbe, Christian Baumann, Matthias Schuster, Kerstin Moehle, Kathryn K. Oi, Erich Michel
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 505-507 (2021)
Heteronuclear NMR in combination with isotope labelling is used to study folding of polypeptides induced by metals in the case of metallothioneins, binding of the peptidic allosteric modulator ρ-TIA to the human G-protein coupled α1b adrenergic rec
Externí odkaz:
https://doaj.org/article/32246dcffb5144bcb3d8acd2ee56e3b5
Autor:
Sabina Schütz, Erich Michel, Fred F. Damberger, Michaela Oplová, Cohue Peña, Alexander Leitner, Ruedi Aebersold, Frederic H.-T. Allain, Vikram Govind Panse
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Ribosomal proteins are transported to the nucleus with the help of importins, from which they are released prior to incorporation into the nascent ribosome. Here the authors report the NMR structure of the ribosomal protein eS26 in complex with the e
Externí odkaz:
https://doaj.org/article/6a9a3ed39ff54d0fae4c92979ac96f5c
Autor:
Kathryn K Oi, Matthias Schuster, Oliver Zerbe, Kerstin Moehle, Christian R. Baumann, Erich Michel
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 505-507 (2021)
Heteronuclear NMR in combination with isotope labelling is used to study folding of polypeptides induced by metals in the case of metallothioneins, binding of the peptidic allosteric modulator ?-TIA to the human G-protein coupled ?1b adrenergic recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a694d4b2d57c7f7a7b6add091cbd6d80
https://doi.org/10.5167/uzh-215485
https://doi.org/10.5167/uzh-215485
Autor:
Christian Taube, Christine Tertilt, Gabor Gyülveszi, Nina Dehzad, Katharina Kreymborg, Kristin Schneeweiss, Erich Michel, Sebastian Reuter, Jean-Christophe Renauld, Danielle Arnold-Schild, Hansjörg Schild, Roland Buhl, Burkhard Becher
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21799 (2011)
Interleukin (IL)-22 is an effector cytokine, which acts primarily on epithelial cells in the skin, gut, liver and lung. Both pro- and anti-inflammatory properties have been reported for IL-22 depending on the tissue and disease model. In a murine mod
Externí odkaz:
https://doaj.org/article/85a04ec9fb114ed1b21edbb64297cbef
MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans
Autor:
André P. Gerber, Nitish Mittal, Jochen Imig, Luca Ducoli, Frédéric H.-T. Allain, Ines Kohler, Anneke Brümmer, Jonathan Hall, Alexander Kanitz, Michael O. Hengartner, Xue Zheng, Deni Subasic, Andres Kaech, Ana M. Matia-González, Yibo Wu, Kapil Dev Singh, Erich Michel, Mihaela Zavolan, Shivendra Kishore, Martin Keller, Ataman Sendoel, Ruedi Aebersold
Publikováno v:
Cell Death Differ
Cell Death and Differentiation, 26 (10)
Cell Death and Differentiation, 26 (10)
Post-transcriptional control of mRNAs by RNA-binding proteins (RBPs) has a prominent role in the regulation of gene expression. RBPs interact with mRNAs to control their biogenesis, splicing, transport, localization, translation, and stability. Defec
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1737
Posttranscriptional regulation of gene expression by small noncoding RNAs (sRNAs) is an important control mechanism that modulates bacterial metabolism, motility, and pathogenesis. Using the bacterial carbon storage regulator/regulator of secondary m
Publikováno v:
Methods in Molecular Biology ISBN: 9781493976331
Posttranscriptional regulation of gene expression by small noncoding RNAs (sRNAs) is an important control mechanism that modulates bacterial metabolism, motility, and pathogenesis. Using the bacterial carbon storage regulator/regulator of secondary m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60835ee571b087a2fac736bf72c51c6
https://doi.org/10.1007/978-1-4939-7634-8_11
https://doi.org/10.1007/978-1-4939-7634-8_11
Publikováno v:
Angewandte Chemie (International ed. in English). 57(17)
Herein, we present the peptide-guided assembly of complementary fragments of designed armadillo repeat proteins (dArmRPs) to create proteins that bind peptides not only with high affinity but also with good selectivity. We recently demonstrated that