Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Erica Yada"'
Autor:
Xuan Du, Erica Yada, Yuki Terai, Takuya Takahashi, Hideyuki Nakanishi, Hiroki Tanaka, Hidetaka Akita, Keiji Itaka
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2291 (2023)
The growing significance of messenger RNA (mRNA) therapeutics in diverse medical applications, such as cancer, infectious diseases, and genetic disorders, highlighted the need for efficient and safe delivery systems. Lipid nanoparticles (LNPs) have s
Externí odkaz:
https://doaj.org/article/bbea13e3452e44a6b84880f314df846f
Autor:
Jia Deng, Yuta Fukushima, Kosuke Nozaki, Hideyuki Nakanishi, Erica Yada, Yuki Terai, Kenji Fueki, Keiji Itaka
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1785 (2022)
Messenger RNA (mRNA) is an emerging drug modality for protein replacement therapy. As mRNA efficiently provides protein expression in post-mitotic cells without the risk of insertional mutagenesis, direct delivery of mRNA can be applied, not only as
Externí odkaz:
https://doaj.org/article/916d013a03e4460db62174803c5654ef
Autor:
Ryotaro Ohkuma, Erica Yada, Shumpei Ishikawa, Daisuke Komura, Hidenobu Ishizaki, Koji Tamada, Yutaro Kubota, Kazuyuki Hamada, Hiroo Ishida, Yuya Hirasawa, Hirotsugu Ariizumi, Etsuko Satoh, Midori Shida, Makoto Watanabe, Rie Onoue, Kiyohiro Ando, Junji Tsurutani, Kiyoshi Yoshimura, Takehiko Yokobori, Tetsuro Sasada, Takeshi Aoki, Masahiko Murakami, Tomoko Norose, Nobuyuki Ohike, Masafumi Takimoto, Masahiko Izumizaki, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226707 (2020)
Pancreatic cancer has an extremely poor prognosis, and identification of novel predictors of therapeutic efficacy and prognosis is urgently needed. Chemoresistance-related molecules are correlated with poor prognosis and may be effective targets for
Externí odkaz:
https://doaj.org/article/2516b1d1f4a1457cbd0daf1c90b6b292
Possible Role of Cytochrome P450 1B1 in the Mechanism of Gemcitabine Resistance in Pancreatic Cancer
Autor:
Erica Yada, Rika Kasajima, Atsushi Niida, Seiya Imoto, Satoru Miyano, Yohei Miyagi, Tetsuro Sasada, Satoshi Wada
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1396 (2021)
Patient-derived xenograft models reportedly represent original tumor morphology and gene mutation profiles. In addition, patient-derived xenografts are expected to recapitulate the parental tumor drug responses. In this study, we analyzed the pathway
Externí odkaz:
https://doaj.org/article/42d60ee7078340bcba2fa833e48b455c
Autor:
Inès Barthélémy, Fernanda Pinto-Mariz, Erica Yada, Loïc Desquilbet, Wilson Savino, Suse Dayse Silva-Barbosa, Anne-Marie Faussat, Vincent Mouly, Thomas Voit, Stéphane Blot, Gillian Butler-Browne
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1253-1261 (2014)
In the translational process of developing innovative therapies for DMD (Duchenne muscular dystrophy), the last preclinical validation step is often carried out in the most relevant animal model of this human disease, namely the GRMD (Golden Retrieve
Externí odkaz:
https://doaj.org/article/cc076bbc3c5b4b219f19e3d012a8bf2e
Autor:
Shumpei Ishikawa, Satoshi Wada, Makoto Watanabe, Yutaro Kubota, Masahiko Murakami, Kiyoshi Yoshimura, Ryotaro Ohkuma, Hirotsugu Ariizumi, Masafumi Takimoto, Kazuyuki Hamada, Midori Shida, Atsushi Horiike, Junji Tsurutani, Kiyohiro Ando, Rie Onoue, Daisuke Komura, Yuya Hirasawa, Erica Yada, Tomoko Norose, Tetsuro Sasada, Shinichi Kobayashi, Nobuyuki Ohike, Takuya Tsunoda, Takeshi Aoki, Tomoyuki Ishiguro
Publikováno v:
Oncology Reports
Pancreatic cancer has extremely poor prognosis, warranting the discovery of novel therapeutic and prognostic markers. The expression of polymeric immunoglobulin receptor (pIgR), a key component of the mucosal immune system, is increased in several ca
Possible Role of Cytochrome P450 1B1 in the Mechanism of Gemcitabine Resistance in Pancreatic Cancer
Autor:
Atsushi Niida, Satoshi Wada, Erica Yada, Tetsuro Sasada, Yohei Miyagi, Rika Kasajima, Seiya Imoto, Satoru Miyano
Publikováno v:
Biomedicines
Volume 9
Issue 10
Biomedicines, Vol 9, Iss 1396, p 1396 (2021)
Volume 9
Issue 10
Biomedicines, Vol 9, Iss 1396, p 1396 (2021)
Patient-derived xenograft models reportedly represent original tumor morphology and gene mutation profiles. In addition, patient-derived xenografts are expected to recapitulate the parental tumor drug responses. In this study, we analyzed the pathway
Autor:
Hiroki Yamaue, Satoshi Wada, Ken Shirabe, Tetsuro Sasada, Mariko Tsukagoshi, Seiko Hirono, Erica Yada, Hiroyuki Kuwano, Shintaro Yoshida
Publikováno v:
Oncotarget
Pancreatic cancer involves highly malignant tumors, and the development of new therapeutic strategies is critical. Mesothelin is overexpressed in infiltrating pancreatic cancer cells and plays an important role in the invasion and migration processes
Publikováno v:
Expert Review of Precision Medicine and Drug Development. 2:371-381
Introduction: Accumulating evidence for the feasibility and efficacy of cancer immunotherapy is ushering in a paradigm shift for cancer treatment. Notably, immune checkpoint inhibitors, suc...
Autor:
Masahiko Murakami, Masafumi Takimoto, Midori Shida, Erica Yada, Takuya Tsunoda, Junji Tsurutani, Ryotaro Ohkuma, Nobuyuki Ohike, Satoshi Wada, Shinichi Kobayashi, Hirotsugu Ariizumi, Makoto Watanabe, Kiyoshi Yoshimura, Kazuyuki Hamada, Atsushi Horiike, Shumpei Ishikawa, Yutaro Kubota, Kiyohiro Ando, Tomoyuki Ishiguro, Daisuke Komura, Tomoko Norose, Yuya Hirasawa, Takeshi Aoki, Tetsuro Sasada, Rie Onoue
Publikováno v:
International Journal of Oncology
Pancreatic cancer is associated with an exceedingly poor prognosis, warranting the development of novel therapeutic strategies and discovery of prognostic predictors. Given that chemoresistance-related molecules are reportedly associated with the poo