Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Erica Y Jacobs"'
Autor:
Fred D Mast, Peter C Fridy, Natalia E Ketaren, Junjie Wang, Erica Y Jacobs, Jean Paul Olivier, Tanmoy Sanyal, Kelly R Molloy, Fabian Schmidt, Magdalena Rutkowska, Yiska Weisblum, Lucille M Rich, Elizabeth R Vanderwall, Nicholas Dambrauskas, Vladimir Vigdorovich, Sarah Keegan, Jacob B Jiler, Milana E Stein, Paul Dominic B Olinares, Louis Herlands, Theodora Hatziioannou, D Noah Sather, Jason S Debley, David Fenyö, Andrej Sali, Paul D Bieniasz, John D Aitchison, Brian T Chait, Michael P Rout
Publikováno v:
eLife, Vol 10 (2021)
The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral escape. We therefore generated a large nanobody repertoire to saturate the distinct and hi
Externí odkaz:
https://doaj.org/article/81f21ae91fa645928a68302720f1052b
Autor:
Jean Paul Olivier, Erica Y Jacobs, Junjie Wang, Natalia E Ketaren, Peter C Fridy, Fred D Mast, Tanmoy Sanyal, Kelly R Molloy, Fabian Schmidt, Magdalena Rutkowska, Yiska Weisblum, Lucille M Rich, Elizabeth R Vanderwall, Nicholas Dambrauskas, Vladimir Vigdorovich, Sarah Keegan, Jacob B Jiler, Milana E Stein, Paul Dominic B Olinares, Louis Herlands, Theodora Hatziioannou, D Noah Sather, Jason S Debley, David Fenyö, Andrej Sali, Paul D Bieniasz, John D Aitchison, Brian T Chait, Michael P Rout
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
eLife, Vol 10 (2021)
article-version (status) pre
article-version (number) 1
eLife, Vol 10 (2021)
SUMMARY Despite the great promise of vaccines, the COVID-19 pandemic is ongoing and future serious outbreaks are highly likely, so that multi-pronged containment strategies will be required for many years. Nanobodies are the smallest naturally occurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256e222ad1c80762e3e30acaf14d6531
https://doi.org/10.7554/elife.73027
https://doi.org/10.7554/elife.73027
Autor:
Jean Paul Olivier, Erica Y Jacobs, Junjie Wang, Natalia E Ketaren, Peter C Fridy, Fred D Mast, Tanmoy Sanyal, Kelly R Molloy, Fabian Schmidt, Magdalena Rutkowska, Yiska Weisblum, Lucille M Rich, Elizabeth R Vanderwall, Nicholas Dambrauskas, Vladimir Vigdorovich, Sarah Keegan, Jacob B Jiler, Milana E Stein, Paul Dominic B Olinares, Louis Herlands, Theodora Hatziioannou, D Noah Sather, Jason S Debley, David Fenyö, Andrej Sali, Paul D Bieniasz, John D Aitchison, Brian T Chait, Michael P Rout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63a8e6871ba3013f507ca4315af67294
https://doi.org/10.7554/elife.73027.sa2
https://doi.org/10.7554/elife.73027.sa2
Autor:
Artem A. Serganov, Yael Udi, Milana E. Stein, Valay Patel, Peter C. Fridy, Charles M. Rice, Mohsan Saeed, Erica Y. Jacobs, Brian T. Chait, Michael P. Rout
Publikováno v:
The Journal of biological chemistry. 298(6)
Picornaviruses are small RNA viruses that hijack host cell machinery to promote their replication. During infection, these viruses express two proteases, 2A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514dfce6efb7ff1ba34a8e963a0a0bbf
https://pubmed.ncbi.nlm.nih.gov/35367208
https://pubmed.ncbi.nlm.nih.gov/35367208
Autor:
Brian T. Chait, Kelly R. Molloy, Fabian Schmidt, Erica Y. Jacobs, L.M. Rich, Fred D. Mast, Sarah Keegan, Magdalena Rutkowska, Olinares Pdb, Jiler Jb, Jiayi Wang, Michael P. Rout, Paul D. Bieniasz, Andrej Sali, Jason S. Debley, Jean Paul Olivier, Tanmoy Sanyal, Stein Me, Yiska Weisblum, Natalia E. Ketaren, Vigdorovich, E. R. Vanderwall, Nicholas Dambrauskas, David Fenyö, D. N. Sather, Peter C. Fridy, Theodora Hatziioannou, John D. Aitchison
Publikováno v:
eLife
SUMMARYDespite the great promise of vaccines, the COVID-19 pandemic is ongoing and future serious outbreaks are highly likely, so that multi-pronged containment strategies will be required for many years. Nanobodies are the smallest naturally occurri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4659b3535ad23310db59271ee7fd618a
https://doi.org/10.1101/2021.04.08.438911
https://doi.org/10.1101/2021.04.08.438911
Autor:
Riccardo Pellarin, Ilona Nudelman, Zhiheng Yu, Brian T. Chait, Joanna A. Hogan, Brian D. Slaughter, Javier Fernandez-Martinez, Seung Joong Kim, Jennifer L. Gerton, Charles H. Greenberg, Rosemary Williams, Paula Upla, Barak Raveh, Steven J. Ludtke, Ignacia Echeverria, David L. Stokes, Andrej Sali, Azraa S. Chaudhury, John D. Aitchison, Wenzhu Zhang, Manjunatha Shivaraju, Jay R. Unruh, Thurston Herricks, Christopher W. Akey, Erica Y. Jacobs, Ilan E. Chemmama, Yi Shi, Martin F. Jarrold, Roxana Mironska, Michael P. Rout, M. Jason de la Cruz, Junjie Wang
Publikováno v:
Nature
Nature, Nature Publishing Group, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, Nature Publishing Group, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have impeded a full structural and functional elucidation. Here we determined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf1df4e9114f902daba1f64b28db9fe
https://doi.org/10.1038/nature26003
https://doi.org/10.1038/nature26003
Autor:
Erica Y. Jacobs, James M. Binley, Ileana M. Cristea, Sarah Keegan, Todd M. Greco, Kevin D. Mohammed, Yang Luo, Tommy Tong, Brian T. Chait, David Fenyö, Michael P. Rout, Mark A. Muesing
Publikováno v:
Nature Microbiology. 1
Although genetically compact, HIV-1 commandeers vast arrays of cellular machinery to sustain and protect it during cycles of viral outgrowth. Transposon-mediated saturation linker scanning mutagenesis was used to isolate fully replication-competent v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec4d0e26154f8af7011d12eee8bcfbf
https://doi.org/10.1038/nmicrobiol.2016.68
https://doi.org/10.1038/nmicrobiol.2016.68
Autor:
Alexander Tarakhovsky, Carol C. Gregorio, Andreas Unger, Christopher T. Pappas, Steffen Just, Wolfgang Rottbauer, Wolfgang A. Linke, Laura T. Donlin, Brian T. Chait, Marc-Werner Dobenecker, Erica Y. Jacobs, Martina Krüger, Christian Andresen, Anke Zieseniss, Tobias Voelkel, Eugene Rudensky
Publikováno v:
Genes & Development. 26:114-119
Protein lysine methylation is one of the most widespread post-translational modifications in the nuclei of eukaryotic cells. Methylated lysines on histones and nonhistone proteins promote the formation of protein complexes that control gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ca69bf3dcb3a95d11d4abd57c86a11
https://doi.org/10.1101/gad.177758.111
https://doi.org/10.1101/gad.177758.111
Autor:
Erica Y. Jacobs, Jennifer J. Rossire, Karen E. Tucker, Miguel Lafarga, Maria T. Berciano, A. Gregory Matera, Karl B. Shpargel, Edward K. L. Chan, Ronald A. Conlon, David F. LePage
Publikováno v:
The Journal of Cell Biology
Cajal bodies (CBs) are nuclear suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs). In addition to snRNPs, they are highly enriched in basal transcription and cell cycle factors, the nucleolar proteins fibrillarin (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee800e541ce383941144821a5656d2c
https://doi.org/10.1083/jcb.200104083
https://doi.org/10.1083/jcb.200104083
Autor:
William F. Marzluff, Liming Gao, Erica Y. Jacobs, Mark R. Frey, Wei Wu, Thomas C. Gebuhr, A. Gregory Matera, Thomas C. Ingledue
Publikováno v:
Molecular Biology of the Cell. 10:1653-1663
Coiled bodies (CBs) are nuclear organelles involved in the metabolism of small nuclear RNAs (snRNAs) and histone messages. Their structural morphology and molecular composition have been conserved from plants to animals. CBs preferentially and specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa00c4ce4e2e213254c09f39b66d923
https://doi.org/10.1091/mbc.10.5.1653
https://doi.org/10.1091/mbc.10.5.1653