Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Erica Woollatt"'
Autor:
David F. Callen, Karen M. Lower, G.R. Sutherland, Laurent Villard, Jozef Gecz, Erica Woollatt, Raman Kumar
Publikováno v:
Hormone Research in Paediatrics. 62:208-214
Background/Aims: Two half-brothers with similar malformed genitals, who both inherited a maternally derived t(X;5)(q13;p15) translocation, have a phenotype consistent with partial androgen sensitivity syndrome. The aim was to identify the gene disrup
Autor:
Robert L. Sutherland, Amanda J. Russell, Davendra Segara, Neville F. Hacker, Graham J. Mann, David Y.H. Choong, Tania Nolan, Michelle J. Henderson, David W. Anderson, Ged Brady, Michael J. Davies, Susan M. Henshall, Erica Woollatt, Graeme A. Macdonald, Olufunmilayo I. Olopade, Ronaldo J. Bova, Jennifer L. Clancy, Colin K. W. Watts, Ian G. Campbell
Publikováno v:
Oncogene. 22:5070-5081
EDD (E3 isolated by differential display), located at chromosome 8q22.3, is the human orthologue of the Drosophila melanogaster tumour suppressor gene 'hyperplastic discs' and encodes a HECT domain E3 ubiquitin protein-ligase. To investigate the poss
Autor:
Lyn Hinton, Meryl Altree, Grant R. Sutherland, Eric Haan, David F. Callen, Elizabeth Thompson, Angus Dobbie, Elizabeth Baker, P. W. Thompson, Helen J. Eyre, Erica Woollatt
Publikováno v:
American Journal of Medical Genetics. 107:285-293
Cryptic subtelomeric chromosome anomalies have been recognized as a significant cause of dysmorphology and mental retardation. To determine whether the clinical cytogenetics laboratory should screen routinely for these aberrations, we have tested 250
Autor:
Geoffrey W. McCaughan, Denise M. T. Yu, Grant R. Sutherland, Mark D. Gorrell, Erica Woollatt, Catherine A. Abbott
Publikováno v:
European Journal of Biochemistry. 267:6140-6150
Dipeptidyl peptidase (DPP) IV has roles in T-cell costimulation, chemokine biology, type-II diabetes and tumor biology. Fibroblast activation protein (FAP) has been implicated in tumor growth and cirrhosis. Here we describe DPP8, a novel human postpr
Autor:
Charles Claudianos, Makoto Kamei, Sumio Sugano, Grant R. Sutherland, Erica Woollatt, Hugh Campbell, Munetomo Hida, Yutaka Suzuki, Ian G. Young
Publikováno v:
Genomics. 68:89-92
We have cloned cDNA for TTYH1, a human homologue of the Drosophila melanogaster tweety (tty) gene. The 450-residue predicted protein shows 27% amino acid sequence identity (51% similarity) to the Drosophila protein, which contains an additional C-ter
Autor:
S M Gartler, R S Hansen, Elizabeth Baker, S Dayan, Oliva Handt, Erica Woollatt, Robert I. Richards
Publikováno v:
Chromosome Research. 8:677-688
The molecular basis for the cytogenetic appearance of chromosomal fragile sites is not yet understood. Late replication and further delay of replication at fragile sites expressing alleles has been observed for FRAXA, FRAXE and FRA3B fragile site loc
Autor:
Mathew A. Vadas, Jennifer R. Gamble, Joanna Crawford, Kazuaki Hiki, Richard J D'Andrea, Grant R. Sutherland, Jill Furze, Erica Woollatt
Publikováno v:
Journal of Biological Chemistry. 274:10661-10667
Differential display polymerase chain reaction has been used to isolate genes regulated in vascular endothelial cells by the angiogenic factor vascular endothelial cell growth factor (VEGF). Analysis of one of the bands consistently up-regulated by V
Autor:
Erica Woollatt, Gabriel Kremmidiotis, Tim Chataway, David F. Callen, Rebecca L. Bilton, Ingrid L. Lensink, Grant R. Sutherland
Publikováno v:
Human Molecular Genetics. 8:523-531
Batten disease (juvenile neuronal ceroid lipofuscinosis) is a recessive neurodegenerative disorder of childhood. The gene, CLN3, was recently identified and found to encode a novel 438 amino acid protein of unknown function. In order to gain insight
Autor:
Robert L. Sutherland, Colin K. W. Watts, Erica Woollatt, Michelle J. Callaghan, Amanda J. Russell, Grant R. Sutherland
Publikováno v:
Oncogene. 17:3479-3491
Use of the differential display technique to isolate progestin-regulated genes in T-47D human breast cancer cells led to identification of a novel gene, EDD. The cDNA sequence contains a 2799 amino acid open reading frame sharing 40% identity with th
Autor:
Deon J. Venter, Fleur Hammet, Gino R. Somers, Erica Woollatt, Robert I. Richards, Melissa C. Southey
Publikováno v:
Genomics. 44:127-130
The G-protein-coupled P2Y purinoceptors mediate a variety of physiological effects in response to extracellular nucleotides. With the recent discovery of several new members from a variety of species, the P2Y purinoceptor family now encompasses types