Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Erica Sarchielli"'
Autor:
Paolo Comeglio, Giulia Guarnieri, Sandra Filippi, Ilaria Cellai, Gabriele Acciai, Ian Holyer, Fredrik Zetterberg, Hakon Leffler, Barbro Kahl-Knutson, Erica Sarchielli, Annamaria Morelli, Mario Maggi, Robert J. Slack, Linda Vignozzi
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionGalectin-3 is a pro-fibrotic β-galactoside binding lectin highly expressed in fibrotic liver and implicated in hepatic fibrosis. Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that h
Externí odkaz:
https://doaj.org/article/63192e450fe54462bda8d9eeb27e6b81
Autor:
Giovanni Corona, Giulia Rastrelli, Sara Marchiani, Sandra Filippi, Annamaria Morelli, Erica Sarchielli, Alessandra Sforza, Linda Vignozzi, Mario Maggi
Publikováno v:
The World Journal of Men's Health, Vol 40, Iss 2, Pp 165-178 (2022)
The real epidemiology and the possible consequences of anabolic-androgenic steroids (AAS) use still represent a very tricky task due to the difficulties in the quantification and detection of these drugs. Chronic use of AAS, frequently combined with
Externí odkaz:
https://doaj.org/article/038de056e1ea4f859204f2da97bfc665
Autor:
Giovanni Corona, Giulia Rastrelli, Annamaria Morelli, Erica Sarchielli, Sarah Cipriani, Linda Vignozzi, Mario Maggi
Publikováno v:
The World Journal of Men's Health, Vol 38, Iss 3, Pp 256-270 (2020)
A dichotomic distinction between “organic” and “functional” hypogonadism is emerging. The former is an irreversible condition due to congenital or “acquired” “organic” damage of the brain centers or of the testis. Conversely, the lat
Externí odkaz:
https://doaj.org/article/5c8c7627ad73445c9604d0d1d2c91df7
Cell-based therapy in Alzheimer's disease: Can human fetal cholinergic neurons 'untangle the skein'?
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 12, Pp 2105-2107 (2018)
Externí odkaz:
https://doaj.org/article/c006b36ce7e245bb9d46a0afda154c00
Autor:
Annamaria Morelli, Erica Sarchielli, Giulia Guarnieri, Elisabetta Coppi, Daniela Pantano, Paolo Comeglio, Pamela Nardiello, Anna M. Pugliese, Lara Ballerini, Rosanna Matucci, Stefano Ambrosini, Giuseppe Castronovo, Rosa Valente, Benedetta Mazzanti, Sandra Bucciantini, Mario Maggi, Fiorella Casamenti, Pasquale Gallina, Gabriella B. Vannelli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The degeneration of cholinergic neurons of the nucleus basalis of Meynert (NBM) in the basal forebrain (BF) is associated to the cognitive decline of Alzheimer’s disease (AD) patients. To date no resolutive therapies exist. Cell-based replacement t
Externí odkaz:
https://doaj.org/article/f59531ff79ea4a4d989e2d27d6dd62d8
Autor:
Annamaria Morelli, Paolo Comeglio, Erica Sarchielli, Ilaria Cellai, Linda Vignozzi, Gabriella B. Vannelli, Mario Maggi
Publikováno v:
International Journal of Endocrinology, Vol 2013 (2013)
Metabolic disorders are often associated with male hypogonadotropic hypogonadism, suggesting that hypothalamic defects involving GnRH neurons may impair the reproductive function. Among metabolic factors hyperglycemia has been implicated in the contr
Externí odkaz:
https://doaj.org/article/a4542e4437464212bc1a7890d6b27439
Autor:
Ilaria Cellai, Paolo Comeglio, Sandra Filippi, Serena Martinelli, Fabio Villanelli, Francesca Amore, Elena Rapizzi, Elisa Maseroli, Sarah Cipriani, Chiara Raddi, Giulia Guarnieri, Erica Sarchielli, Giovanna Danza, Annamaria Morelli, Giulia Rastrelli, Mario Maggi, Linda Vignozzi
Publikováno v:
The Journal of Sexual Medicine. 20:1-13
BackgroundSex steroids have been demonstrated as important modulators of vaginal function. The RhoA/ROCK calcium-sensitizing pathway plays a role in genital smooth muscle contractile mechanism, but its regulation has never been elucidated.AimThis stu
Autor:
Tommaso Mello, Andrea Galli, Mario Maggi, Paolo Comeglio, Ilaria Cellai, Benjamin J Bruno, Sandra Filippi, Elisa Maseroli, Giulia Guarnieri, K. Papangkorn, Erica Sarchielli, K. Vangara, Sarah Cipriani, Annamaria Morelli, N. Chidambaram, Giulia Rastrelli, K. Kim, Linda Vignozzi, M. V. Patel
Publikováno v:
Journal of Endocrinological Investigation
Purpose Low free testosterone (T) level in men is independently associated with presence and severity of Non-Alcoholic Steatohepatitis (NASH). The histological and molecular effects of oral testosterone prodrug LPCN 1144 treatment on hepatic fibrosis
Autor:
Renato Corradetti, Erica Sarchielli, Pasquale Gallina, Annamaria Morelli, Elisabetta Coppi, Gabriella B. Vannelli, Irene Fusco, Anna Maria Pugliese, Giulia Guarnieri, Federica Cherchi, Felicita Pedata
Publikováno v:
Journal of Neurochemistry. 157:1182-1195
The Nucleus Basalis of Meynert (NBM) is the main source of cholinergic neurons in the basal forebrain to be crucially involved in cognitive functions and whose degeneration correlates with cognitive decline in major degenerative pathologies as Alzhei
Autor:
Giulia Rastrelli, Ilaria Cellai, Paolo Comeglio, Erica Sarchielli, Daniele Bani, Sandra Filippi, Elena Rapizzi, Gabriella B. Vannelli, Linda Vignozzi, Mario Maggi, Giulia Guarnieri, Daniele Guasti, Annamaria Morelli
Publikováno v:
Journal of Endocrinology. 245:259-279
Lifestyle modifications, including physical exercise (PhyEx), are well-known treatments for metabolic syndrome (MetS), a cluster of metabolic and cardiovascular risk factors often associated to hypogonadism. Given the trophic role of testosterone on