Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Erica Salerno"'
Autor:
Elizabeth S. Raveche, Gerald Marti, Helen Fernandes, Alessia Baccarini, Brian D. Brown, Frederick D. Coffman, Brian J. Scaglione, Erica Salerno
Supplementary Data from Correcting miR-15a/16 genetic defect in New Zealand Black mouse model of CLL enhances drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a607ed038ecf9582943ab573a6110cbf
https://doi.org/10.1158/1535-7163.22484664.v1
https://doi.org/10.1158/1535-7163.22484664.v1
Autor:
Elizabeth S. Raveche, Gerald Marti, Helen Fernandes, Alessia Baccarini, Brian D. Brown, Frederick D. Coffman, Brian J. Scaglione, Erica Salerno
Alterations in the human 13q14 genomic region containing microRNAs mir-15a and mir-16-1 are present in most human chronic lymphocytic leukemia (CLL). We have previously found the development of CLL in the New Zealand Black murine model to be associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4eb7440a26131bd010c01dc11b00ac
https://doi.org/10.1158/1535-7163.c.6531519.v1
https://doi.org/10.1158/1535-7163.c.6531519.v1
Autor:
Chingiz Underbayev, Siddha Kasar, Erica Salerno, Yao Yuan, Elizabeth Raveche, Daniel Vollenweider, Sergei V. Kotenko
Publikováno v:
Molecular Immunology. 52:61-70
MicroRNAs (miRNAs) are involved in the regulation of immunity via targeting of mRNA encoding immune response elements. In this report, alterations in the expression of microRNAs as autoantibody levels increase was investigated. The (NZB X NZW) F1 or
Autor:
Maria Fernanda Laurindo, Erica Salerno, Sivasubramanian Baskar, Elizabeth Raveche, Fermina Mazzella, Alexander Jankovic, Yao Yuan, Christoph Rader, Gerald E. Marti, Brian J. Scaglione, Daryl Despres
Publikováno v:
Cytometry Part B: Clinical Cytometry. :S98-S109
Background: Similar to a subset of human patients who progress from monoclonal B lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL), New Zealand Black (NZB) mice have an age-associated progression to CLL. The murine disease is linked to a gene
Autor:
Gerald E. Marti, Brian D. Brown, Erica Salerno, Frederick D. Coffman, Alessia Baccarini, Brian J. Scaglione, Helen Fernandes, Elizabeth Raveche
Publikováno v:
Molecular Cancer Therapeutics. 8:2684-2692
Alterations in the human 13q14 genomic region containing microRNAs mir-15a and mir-16-1 are present in most human chronic lymphocytic leukemia (CLL). We have previously found the development of CLL in the New Zealand Black murine model to be associat
Autor:
Steven R. Bauer, Brian J. Scaglione, Vincent K. Tsiagbe, Elizabeth Raveche, Kinisha Gala, Jerome A. Langer, Gerald E. Marti, Erica Salerno, Yu Li, Manjing Pan, Howard Mostowski
Publikováno v:
Journal of Autoimmunity. 32:14-23
Regulatory T cells (Tregs) play an important role in protection against autoimmune disease and are also known to be potent inhibitors of anti-tumor immune responses. The New Zealand Black (NZB) mouse is a murine model for both autoimmune diseases, si
Autor:
Elizabeth Raveche, Frederick D. Coffman, Erica Salerno, Fatima Abbasi, Pablo Landgraf, Brian J. Scaglione, Gerald E. Marti, Sergei V. Kotenko, Murugabaskar Balan
Publikováno v:
British Journal of Haematology. 139:645-657
Summary Mouse models are valuable tools in the study of human chronic lymphocytic leukaemia (CLL). The New Zealand Black (NZB) strain is a naturally occurring model of late-onset CLL characterized by B-cell hyperproliferation and autoimmunity early i
Autor:
Benjamin A. Belinka, Erica Salerno, Scott C. Kachlany, Thomas N. Dam, Karin Stenderup, Cecilia Rosada
Publikováno v:
Stenderup, K, Rosada, C, Dam, T N, Salerno, E, Belinka, B A & Kachlany, S C 2011, ' Resolution of psoriasis by a leukocyte-targeting bacterial protein in a humanized mouse model ', Journal of Investigative Dermatology, vol. 131, no. 10, pp. 2033-9 . https://doi.org/10.1038/jid.2011.161
Psoriasis is a very common chronic skin disease, affecting 2-3% of the world's population or more than 125 million individuals worldwide. The characteristic lesion of psoriasis is due to rapid proliferation and shortened transition of keratinocytes t
A bioluminescent HL-60 cell line to assay anti-leukaemia therapeutics under physiological conditions
Autor:
Erica Salerno, Anna O'Connor, Scott C. Kachlany, Amy Le, Jigna K. Patel, Juan A. Crosby, Jennie T. Chau, Nataliya V. Balashova, Maria P. Isaza
Publikováno v:
Luminescence : the journal of biological and chemical luminescence. 23(1)
Screens for compounds and proteins with anti-cancer activity employ viability assays using relevant cancer cell lines. For leukaemia studies, the human leukaemia cell line, HL-60, is often used as a model system. To facilitate the discovery and inves