Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Erica S. Schwartz"'
Autor:
Ting Wang, Derek C Molliver, Xiaotang Jing, Erica S Schwartz, Fu-Chia Yang, Omar Abdel Samad, Qiufu Ma, Brian M Davis
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28908 (2011)
In adult mammals, the phenotype of half of all pain-sensing (nociceptive) sensory neurons is tonically modulated by growth factors in the glial cell line-derived neurotrophic factor (GDNF) family that includes GDNF, artemin (ARTN) and neurturin (NRTN
Externí odkaz:
https://doaj.org/article/d569b5f849fe406e9a27294cee37ad64
Publikováno v:
Journal of Urology. 196:892-901
Chronic prostatitis/chronic pelvic pain syndrome causes symptoms that include the frequent and urgent need to urinate, pain or burning during urination and pain radiating to the back, abdomen and/or colorectum. These bladder symptoms suggest that chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e744793b2ee86f91538a5000f1553bc0
https://doi.org/10.1016/j.juro.2016.03.077
https://doi.org/10.1016/j.juro.2016.03.077
Publikováno v:
Pain. 156:1537-1544
Chronic nonbacterial prostatitis, characterized by genitourinary pain in the pelvic region in the absence of an identifiable cause, is common in adult males. Surprisingly, the sensory innervation of the prostate and mediators that sensitize its inner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56c491606f87eaafe663e150e64873d
https://doi.org/10.1097/j.pain.0000000000000201
https://doi.org/10.1097/j.pain.0000000000000201
Publikováno v:
Journal of Neurophysiology. 113:2242-2249
Measuring the excitability of individual axons is complicated by the prohibitive difficulty in obtaining intracellular recordings. Here, we present an innovative methodology that enables local excitability to be measured anywhere in a channelrhodopsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f94b2ff3f6f68c46dab57c8f3e75bb
https://doi.org/10.1152/jn.00982.2014
https://doi.org/10.1152/jn.00982.2014
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G638-G648
The ligand-gated channels transient receptor potential vanilloid 1 (TRPV1) and P2X3 have been reported to facilitate colorectal afferent neuron sensitization, thus contributing to organ hypersensitivity and pain. In the present study, we hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd983eff828c0ac7104c960a1f45991
https://doi.org/10.1152/ajpgi.00180.2013
https://doi.org/10.1152/ajpgi.00180.2013
Autor:
Jennifer J. DeBerry, Xiaotang Jing, Ting Wang, Kathryn M. Albers, Brian M. Davis, Derek C. Molliver, Erica S. Schwartz
Publikováno v:
The Journal of Neuroscience. 33:2060-2070
Neurturin (NRTN) is a member of the glial cell line-derived neurotrophic factor family of ligands that exerts its actions via Ret tyrosine kinase and GFRα2. Expression of the Ret–GFRα2 coreceptor complex is primarily restricted to the peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0212ca9c18e860f7abbfb38505802d81
https://doi.org/10.1523/jneurosci.4012-12.2013
https://doi.org/10.1523/jneurosci.4012-12.2013
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G802-G809
Carbohydrate malabsorption such as in lactose intolerance or enteric infection causes symptoms that include abdominal pain. Because this digestive disorder increases intracolonic osmolarity and acidity by accumulation of undigested carbohydrates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35823ef80d266590f4f5f500eb6b1207
https://doi.org/10.1152/ajpgi.00259.2012
https://doi.org/10.1152/ajpgi.00259.2012
Autor:
Timothy P McMurray, Erica S. Schwartz, Jun-Ho La, Bin Feng, Gerald F. Gebhart, Takahiro Tanaka
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G817-G824
Inflammation of the distal bowel is often associated with abdominal pain and hypersensitivity, but whether and which colorectal afferents contribute to the hypersensitivity is unknown. Using a mouse model of 2,4,6-trinitrobenzene sulfonic acid (TNBS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272378d51645e9eb3047b90dac36f9c1
https://doi.org/10.1152/ajpgi.00257.2012
https://doi.org/10.1152/ajpgi.00257.2012
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G1085-G1098
Irritable bowel syndrome (IBS) is characterized as functional because a pathobiological cause is not readily apparent. Considerable evidence, however, documents that sensitizing proinflammatory and lipotoxic lipids, mast cells and their products, try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7bf00c53e96144aad8df894d06fa90
https://doi.org/10.1152/ajpgi.00542.2011
https://doi.org/10.1152/ajpgi.00542.2011
Autor:
Erica S. Schwartz, Derek C. Molliver, Brian M. Davis, Kathryn M. Albers, Pam Cornuet, Julie A. Christianson, Sacha A. Malin
Publikováno v:
Journal of Neuroscience. 31:10516-10528
The nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) families of growth factors regulate the sensitivity of sensory neurons. The ion channels transient receptor potential vanilloid 1 (TRPV1) and transient receptor pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb01083e040a0f424affb874ce05a00
https://doi.org/10.1523/jneurosci.2992-10.2011
https://doi.org/10.1523/jneurosci.2992-10.2011