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pro vyhledávání: '"Erica S. Dyer"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 4, Pp 331-338 (2001)
Phenylbutyrate (PB) is a histone deacetylase inhibitor that has been shown to induce differentiation and apoptosis in various cancer cell lines. Although these effects are most likely due to modulation of gene expression, the specific genes and gene
Externí odkaz:
https://doaj.org/article/9d0bb434417f490791f28ff87d27fcdf
Autor:
Donna L. Livant, Sonja Markwart, Mats Ljungman, Michelle T. Paulsen, Erica S. Dyer, Meidee Goh
Publikováno v:
International Journal of Cancer. 101:496-499
Histone deacetylase inhibitors, such as phenylbutyrate, are currently undergoing clinical trials as potential anticancer agents. Phenylbutyrate can induce cell differentiation and apoptosis in a number of cancer cell types and can act in synergy with
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 4, Pp 331-338 (2001)
Phenylbutyrate (PB) is a histone deacetylase inhibitor that has been shown to induce differentiation and apoptosis in various cancer cell lines. Although these effects are most likely due to modulation of gene expression, the specific genes and gene