Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Erica P. Homan"'
Publikováno v:
Journal of Microbiology & Biology Education, Vol 23, Iss 1 (2022)
ABSTRACT Although various resources exist for facilitating online laboratory courses, stitching together disparate elements from multiple sources may not be sufficient to meet the learning goals of a given course. For example, our Biology Project Lab
Externí odkaz:
https://doaj.org/article/2cd07dbab35d43eb9a0bf8e01903010b
Autor:
Masaji Sakaguchi, Weikang Cai, Chih-Hao Wang, Carly T. Cederquist, Marcos Damasio, Erica P. Homan, Thiago Batista, Alfred K. Ramirez, Manoj K. Gupta, Martin Steger, Nicolai J. Wewer Albrechtsen, Shailendra Kumar Singh, Eiichi Araki, Matthias Mann, Sven Enerbäck, C. Ronald Kahn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Insulin signaling represses Forkhead transcription factor FoxO activity, which contributes to organismal metabolism. Here, the authors use proteomics to identify positively regulated insulin signaling targets FoxK1/K2 and demonstrate their role in li
Externí odkaz:
https://doaj.org/article/6452f44069924205846a1027bdcd7038
Publikováno v:
Journal of microbiologybiology education. 23(1)
Although various resources exist for facilitating online laboratory courses, stitching together disparate elements from multiple sources may not be sufficient to meet the learning goals of a given course. For example, our Biology Project Lab course i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d69f45c0d7bba37ed616ed8511220b
https://pubmed.ncbi.nlm.nih.gov/35496697
https://pubmed.ncbi.nlm.nih.gov/35496697
Autor:
Thiago M. Batista, C. Ronald Kahn, Alfred K. Ramirez, Eiichi Araki, Martin Steger, Weikang Cai, Shailendra Kumar Singh, Nicolai J. Wewer Albrechtsen, Marcos Damasio, Matthias Mann, Manoj K. Gupta, Erica P. Homan, Masaji Sakaguchi, Chih-Hao Wang, Carly T. Cederquist, Sven Enerbäck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Sakaguchi, M, Cai, W, Wang, C-H, Cederquist, C T, Damasio, M, Homan, E P, Batista, T, Ramirez, A K, Gupta, M K, Steger, M, Wewer Albrechtsen, N J, Singh, S K, Araki, E, Mann, M, Enerbäck, S & Kahn, C R 2019, ' FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism ', Nature Communications, vol. 10, no. 1, 1582 . https://doi.org/10.1038/s41467-019-09418-0
Nature Communications
Sakaguchi, M, Cai, W, Wang, C-H, Cederquist, C T, Damasio, M, Homan, E P, Batista, T, Ramirez, A K, Gupta, M K, Steger, M, Wewer Albrechtsen, N J, Singh, S K, Araki, E, Mann, M, Enerbäck, S & Kahn, C R 2019, ' FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism ', Nature Communications, vol. 10, no. 1, 1582 . https://doi.org/10.1038/s41467-019-09418-0
A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which translocate from the nucleus to the cytoplasm following insulin-stimulated phosphorylation. Here we show that the Forkhead transcription factors FoxK1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2ea2a65dfb089997f1d72b587591ed
https://doaj.org/article/6452f44069924205846a1027bdcd7038
https://doaj.org/article/6452f44069924205846a1027bdcd7038
Autor:
Erica P Homan, Caressa Lietman, Ingo Grafe, Jennifer Lennington, Roy Morello, Dobrawa Napierala, Ming-Ming Jiang, Elda M Munivez, Brian Dawson, Terry K Bertin, Yuqing Chen, Rhonald Lua, Olivier Lichtarge, John Hicks, Mary Ann Weis, David Eyre, Brendan H L Lee
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004121 (2014)
Mutations in the genes encoding cartilage associated protein (CRTAP) and prolyl 3-hydroxylase 1 (P3H1 encoded by LEPRE1) were the first identified causes of recessive Osteogenesis Imperfecta (OI). These proteins, together with cyclophilin B (encoded
Externí odkaz:
https://doaj.org/article/37ae85070b0b4400b4a292992ff153e7
Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue
Autor:
Rohit N. Kulkarni, Abdelfattah El Ouaamari, Jason K. Kim, Erica P. Homan, C. Ronald Kahn, Samir Softic, Brian T. O’Neill, Bruna B. Brandão
Publikováno v:
J Clin Invest
Insulin and IGF-1 are essential for adipocyte differentiation and function. Mice lacking insulin and IGF-1 receptors in fat (FIGIR-KO, fat-specific IGF-1 receptor and insulin receptor-KO) exhibit complete loss of white and brown adipose tissue (WAT a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8793bfa26f122927cdc28e01c562eea7
https://pubmed.ncbi.nlm.nih.gov/34428182
https://pubmed.ncbi.nlm.nih.gov/34428182
Autor:
C. Ronald Kahn, Shiho Fujisaka, Jeremie Boucher, Jonathon N. Winnay, Antonio R. Perez-Atayde, Max-Felix Haering, Samir Softic, Erica P. Homan, Marie H. Solheim
Publikováno v:
Diabetes
Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5fe29c5408180764a939caf3a76d11e
https://doi.org/10.2337/db16-0213
https://doi.org/10.2337/db16-0213
Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1 null mice
Autor:
Masataka Suzuki, Racel Cela, Terry Bertin, Kyu Sang Joeng, Ming-Ming Jiang, Abbhirami Rajagopal, Elda Munivez, Frank Gannon, Brian Dawson, Erica P. Homan, Brendan Lee, Susan E. Crawford
Publikováno v:
Molecular Genetics and Metabolism. 117:378-382
Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by bone fragility and deformity. OI type VI is unique owing to the mineralization defects observed in patient biopsies. Furthermore, it has been reported to respond less well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aa59d2ccae4dcf4f04740eb5cbd777
https://doi.org/10.1016/j.ymgme.2015.11.015
https://doi.org/10.1016/j.ymgme.2015.11.015
Autor:
Stefanie Alexander, Terry Bertin, Franklin J. Asuncion, Brendan Lee, Ming Ming Jiang, Tao Yang, Ingo Grafe, Hua Zhu Ke, Brian Dawson, Michael S. Ominsky, Caressa Lietman, Elda Munivez, Erica P. Homan, Yuqing Chen
Publikováno v:
Journal of Bone and Mineral Research. 31:1030-1040
Osteogenesis imperfecta (OI) is characterized by low bone mass, poor bone quality, and fractures. Standard treatment for OI patients is limited to bisphosphonates, which only incompletely correct the bone phenotype, and seem to be less effective in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c562e0bade0147538ef32b3680ed87
https://doi.org/10.1002/jbmr.2776
https://doi.org/10.1002/jbmr.2776
Autor:
John Hicks, Ming Ming Jiang, Abbhirami Rajagopal, Terry Bertin, Yuqing Chen, MaryAnn Weis, Deborah Krakow, Erica P. Homan, Elda Munivez, David R. Eyre, Brendan Lee, Caressa Lietman
Osteogenesis imperfecta (OI) is an inherited brittle bone disorder characterized by bone fragility and low bone mass. Loss of function mutations in FK506-binding protein 10 (FKBP10), encoding the FKBP65 protein, result in recessive OI and Bruck syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4311519be1140e82468fd623584358e
https://europepmc.org/articles/PMC4140464/
https://europepmc.org/articles/PMC4140464/
