Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Erica N. Montano"'
Autor:
Gantsetseg Tumurkhuu, Nancy G. Casanova, Carrie L. Kempf, Duygu Ercan Laguna, Sara M. Camp, Jargalsaikhan Dagvadorj, Jin H. Song, Vivian Reyes Hernon, Cristina Travelli, Erica N. Montano, Jeong Min Yu, Mariko Ishimori, Daniel J. Wallace, Saad Sammani, Caroline Jefferies, Joe G.N. Garcia
Publikováno v:
Journal of Translational Autoimmunity, Vol 6, Iss , Pp 100181- (2023)
Rationale: Effective therapies to reduce the severity and high mortality of pulmonary vasculitis and diffuse alveolar hemorrhage (DAH) in patients with systemic lupus erythematosus (SLE) is a serious unmet need. We explored whether biologic neutraliz
Externí odkaz:
https://doaj.org/article/8b7438a4b64745b39ec0c97c6e32db85
Autor:
Gantsetseg Tumurkhuu, Duygu Ercan Laguna, Richard E. Moore, Jorge Contreras, Gabriela De Los Santos, Luisa Akaveka, Erica N. Montano, Yizhou Wang, Mariko Ishimori, Swamy Venuturupalli, Lindsy J. Forbess, Barry R. Stripp, Daniel J. Wallace, Caroline A. Jefferies
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Diffuse alveolar hemorrhage (DAH), although rare, is a life-threatening complication of systemic lupus erythematosus (SLE). Little is known about the pathophysiology of DAH in humans, although increasingly neutrophils, NETosis and inflammatory monocy
Externí odkaz:
https://doaj.org/article/16d6495b0a4a4ec9b252b49043fdb93d
Autor:
Gantsetseg Tumurkhuu, Shuang Chen, Erica N. Montano, Duygu Ercan Laguna, Gabriela De Los Santos, Jeong Min Yu, Malcolm Lane, Michifumi Yamashita, Janet L. Markman, Luz P. Blanco, Mariana J. Kaplan, Kenichi Shimada, Timothy R. Crother, Mariko Ishimori, Daniel J. Wallace, Caroline A. Jefferies, Moshe Arditi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease in which type I interferons (IFN) play a key role. The IFN response can be triggered when oxidized DNA engages the cytosolic DNA sensing platform cGAS-STING, but the repa
Externí odkaz:
https://doaj.org/article/804a8420fafe4285aba0bf129953d581
Autor:
Ayelet Gonen, Lotte F. Hansen, William W. Turner, Erica N. Montano, Xuchu Que, Apaїs Rafia, Meng-Yun Chou, Philipp Wiesner, Dimitrios Tsiantoulas, Maripat Corr, Michael S. VanNieuwenhze, Sotirios Tsimikas, Christoph J. Binder, Joseph L. Witztum, Karsten Hartvigsen
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2137-2155 (2014)
Immunization with homologous malondialdehyde (MDA)-modified LDL (MDA-LDL) leads to atheroprotection in experimental models supporting the concept that a vaccine to oxidation-specific epitopes (OSEs) of oxidized LDL could limit atherogenesis. However,
Externí odkaz:
https://doaj.org/article/df6705f6871340f0ba50bdf157e780be
Autor:
Erica N. Montano, Agnès Boullier, Felicidad Almazan, Christoph J. Binder, Joseph L. Witztum, Karsten Hartvigsen
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3206-3214 (2013)
Macrophages play a key role in atherogenesis in part through excessive uptake of oxidized LDL (OxLDL) via scavenger receptors. Binding of OxLDL to macrophages has traditionally been assessed using radiolabeled OxLDL. To allow more efficient and conve
Externí odkaz:
https://doaj.org/article/251ca97b7da54ac38a00670e745e672e
Autor:
Alexander Hooftman, Christian G. Peace, Dylan G. Ryan, Emily A. Day, Ming Yang, Anne F. McGettrick, Maureen Yin, Erica N. Montano, Lihong Huo, Juliana E. Toller-Kawahisa, Vincent Zecchini, Tristram A. J. Ryan, Alfonso Bolado-Carrancio, Alva M. Casey, Hiran A. Prag, Ana S. H. Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J. Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander Von Kriegsheim, Michael P. Murphy, Caroline Jefferies, Christian Frezza, Luke A. J. O’Neill
Publikováno v:
Hooftman, A, G. Peace, C, G. Ryan, D, A. Day, E, Yang, M, F. McGettrick, A, Yin, M, N. Montano, E, Huo, L, E. Toller-Kawahisa, J, Zecchini, V, A. J. Ryan, T, Bolado Carrancio, A, M. Casey, A, A. Prag, H, S.H. Costa, A, De Los Santos, G, Ishimori, M, J. Wallace, D, Venuturupalli, S, Nikitopoulou, E, Frizzell, N, Johansson, C, von Kriegsheim, A, P. Murphy, M, Jefferies, C, Frezza, C & A.J. O'Neill, L 2023, ' Macrophage fumarate hydratase restrains mtRNA-mediated interferon production ', Nature, vol. 615, pp. 490-498 . https://doi.org/10.1038/s41586-023-05720-6
Metabolic rewiring underlies the effector functions of macrophages 1–3, but the mechanisms involved remain incompletely defined. Here, using unbiased metabolomics and stable isotope-assisted tracing, we show that an inflammatory aspartate–arginin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1440c30dd8894932c61643e40d2cc0cc
http://hdl.handle.net/10044/1/104575
http://hdl.handle.net/10044/1/104575
Autor:
Erica N Montano, Moumita Bose, Lihong Huo, Gantsetseg Tumurkhuu, Gabriela De Los Santos, Aleksandr B Stotland, Janet Wei, C Noel Bairey Merz, Gislaine Martins, Sarfaraz Lalani, Kate Lawrenson, Sarah Parker, Mariko Ishimori, Daniel J Wallace, Caroline Jefferies
Publikováno v:
SLE Diagnosis.
Autor:
Mariko L. Ishimori, Duygu Ercan Laguna, Luisa Akaveka, Daniel J. Wallace, Wonwoo Shon, Erica N. Montano, Gantsetseg Tumurkhuu, Gabriela de los Santos, Rachel Abuav, Caroline A. Jefferies
Publikováno v:
Abstracts.
Autor:
Gantsetseg Tumurkhuu, Duygu Ercan Laguna, Richard E. Moore, Jorge Contreras, Gabriela De Los Santos, Luisa Akaveka, Erica N. Montano, Yizhou Wang, Mariko Ishimori, Swamy Venuturupalli, Lindsy J. Forbess, Barry R. Stripp, Daniel J. Wallace, Caroline A. Jefferies
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Diffuse alveolar hemorrhage (DAH), although rare, is a life-threatening complication of systemic lupus erythematosus (SLE). Little is known about the pathophysiology of DAH in humans, although increasingly neutrophils, NETosis and inflammatory monocy
Autor:
Moore Re, De Los Santos G, Akaveka L, Mariko L. Ishimori, Caroline A. Jefferies, Gantsetseg Tumurkhuu, Daniel J. Wallace, Yang Wang, Swamy Venuturupalli, Erica N. Montano, Contreras J, Ercan Laguna D, Lindsy J. Forbess
Diffuse alveolar hemorrhage (DAH), although rare, is a life-threatening complication of systemic lupus erythematosus (SLE). Little is known about the pathophysiology of DAH in humans, although increasingly neutrophils, NETosis and inflammatory monocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a14d9faec6c362be1b33393f2473f78
https://doi.org/10.1101/2021.10.01.462788
https://doi.org/10.1101/2021.10.01.462788