Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Erica Maria Pimenta"'
Autor:
Gabrielle Bouchard, Wenxin Xu, David L. Cookmeyer, Bradley Alexander McGregor, Kelly Street, Ziad Bakouny, Arlene H. Sharpe, Christina B. Pedersen, Lucas Pomerance, Nicholas Schindler, Sachet A. Shukla, Erica Maria Pimenta, Rafael A. Irizarry, Kathleen M. Mahoney, John A. Steinharter, Ang Cui, Kelly P. Burke, Juliet Forman, Steven L. Chang, Michelle S. Hirsch, Maxine Sun, Catherine J. Wu, Lars Rønn Olsen, Sabina Signoretti, David A. Braun, Derin B. Keskin, Toni K. Choueiri, Kenneth J. Livak, Shuqiang Li, Yue Hou, David F. McDermott, Satyen H. Gohil, Teddy Huang, Laure Hirsch, Thomas Denize
Publikováno v:
Cancer Cell
The tumor immune microenvironment plays a critical role in cancer progression and response to immunotherapy in clear cell renal cell carcinoma (ccRCC), yet the composition and phenotypic states of immune cells in this tumor are incompletely character
Autor:
Betsy J. Barnes, Kelly Hall, Di Feng, Sarah Kilic, Shridar Ganesan, Saurav De, Erica Maria Pimenta, Sophia Ran, Gyan Bhanot, Ryan Weiss
Publikováno v:
Immunology & Cell Biology. 93:486-499
Clinical studies using prognostic and predictive signatures have shown that an immune signal emanating from whole tumors reflects the level of immune cell infiltration--a high immune signal linked to improved outcome. Factors regulating immune cell t
Autor:
Dan Li, Gulam Waris, Erdene Baljinnyam, Neerja Kaushik-Basu, Ozge Cevik, Betsy J. Barnes, Dinesh Manvar, Erica Maria Pimenta
Publikováno v:
The Journal of biological chemistry. 292(52)
WOS: 000419013000041
PubMed ID: 29079574
Hepatitis C virus (HCV) infection is a major risk factor for the development of chronic liver disease. The disease typically progresses from chronic HCV to fibrosis, cirrhosis, hepatocellular carcino
PubMed ID: 29079574
Hepatitis C virus (HCV) infection is a major risk factor for the development of chronic liver disease. The disease typically progresses from chronic HCV to fibrosis, cirrhosis, hepatocellular carcino
Autor:
Erica Maria Pimenta, Betsy J. Barnes
Publikováno v:
Molecular Cancer
Background Migration of breast cancer cells out of a duct or lobule is a prerequisite for invasion and metastasis. However, the factors controlling breast cancer cell migration are not fully elucidated. We previously found that expression of the tran
Autor:
Erica Maria Pimenta, Betsy J. Barnes
Publikováno v:
Cancers
Cancers, Vol 6, Iss 2, Pp 969-997 (2014)
Cancers, Vol 6, Iss 2, Pp 969-997 (2014)
Following the successes of monoclonal antibody immunotherapies (trastuzumab (Herceptin®) and rituximab (Rituxan®)) and the first approved cancer vaccine, Provenge® (sipuleucel-T), investigations into the immune system and how it can be modified by
Publikováno v:
Cancer Research. 76:4141-4141
The ability of breast cancer cells to metastasize is due to intrinsic intratumoral and extrinsic microenvironment changes. Many breast cancers are heavily infiltrated by immune cells and these infiltrating leukocytes are commonly observed around tumo
Autor:
Erica Maria Pimenta, Betsy J. Barnes
Publikováno v:
Cancer Research. 73:P5-04
Staining of over 300 human breast cancer tissue samples demonstrates that over 75% of invasive ductal carcinomas, regardless of subtype, have lost expression of interferon regulatory factor 5 (IRF5). Loss of IRF5 correlates with higher tumor grades,
Publikováno v:
Breast Cancer Research : BCR
Introduction New signaling pathways of the interleukin (IL) family, interferons (IFN) and interferon regulatory factors (IRF) have recently been found within tumor microenvironments and in metastatic sites. Some of these cytokines stimulate while oth