Výsledky vyhledávání - "Erica Marchlik"

Data from RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients

Autor: Razelle Kurzrock, Jennifer L. Carter, Sheryl K. Elkin, Erica Marchlik, Vivek Subbiah, Shumei Kato

Purpose: Aberrations in genetic sequences encoding the tyrosine kinase receptor RET lead to oncogenic signaling that is targetable with anti-RET multikinase inhibitors. Understanding the comprehensive genomic landscape of RET aberrations across multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff9d92afdf8ce7fe17bbefd310cef3
https://doi.org/10.1158/1078-0432.c.6526431.v1

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Supplemental Tables 1-7 and Supplemental Figure 1 from RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients

Autor: Razelle Kurzrock, Jennifer L. Carter, Sheryl K. Elkin, Erica Marchlik, Vivek Subbiah, Shumei Kato

Supplemental Table 1. Selected ongoing clinical trials targeting RET aberrations; Supplemental Table 2. Cancer diagnosis that were negative for RET aberration (included cases with N {greater than or equal to}10); Supplemental Table 3. Complete list o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce31893ac816852f3efcdb2c1105829
https://doi.org/10.1158/1078-0432.22466784

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RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients

Autor: Razelle Kurzrock, Shumei Kato, Vivek Subbiah, Erica Marchlik, Jennifer L. Carter, Sheryl Krevsky Elkin

Publikováno v: Clinical Cancer Research. 23:1988-1997

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d3b516400a7dc5cd5f9e92de748e6
https://doi.org/10.1158/1078-0432.ccr-16-1679

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Targetable mutations in gastrointestinal malignancies: A comparison of RAS mutant and RAS wild type tumors

Autor: Dan Barnett, Jamie Randall, Sarah Mullaly, Gail Payne, Erica Marchlik, Sheryl Krevsky Elkin, Danny Rayes, Hongkun Wang, Raymond C. Wadlow, Lindsey Tishman, Timothy L. Cannon

Publikováno v: Journal of Clinical Oncology. 39:129-129

129 Background: KRAS and NRAS (RAS) mutations are considered driver mutations in gastrointestinal malignancies such as colorectal and pancreatic cancer. Our institution obtains broad molecular testing (commercial panels with full exon coverage of at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9efe756b61a0ee4206ca4ad621b3b26b
https://doi.org/10.1200/jco.2021.39.3_suppl.129

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Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics

Autor: Erica Marchlik, Sheryl Krevsky Elkin, Razelle Kurzrock, Brett N. Tomson, Jennifer L. Carter, Philip R. Cohen

Publikováno v: Cohen, PR; Tomson, BN; Elkin, SK; Marchlik, E; Carter, JL; & Kurzrock, R. (2016). Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics. ONCOTARGET, 7(17), 23454-23467. doi: 10.18632/oncotarget.8032. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3xn6s72f
Oncotarget
Oncotarget, vol 7, iss 17

Merkel cell carcinoma is an ultra-rare cutaneous neuroendocrine cancer for which approved treatment options are lacking. To better understand potential actionability, the genomic landscape of Merkel cell cancers was assessed. The molecular aberration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcd1d62748764b0331cf58672d693d5
http://www.escholarship.org/uc/item/3xn6s72f

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Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality

Autor: G. Roger Askew, Tianhui Zhou, Victoria Roberts, Katherine A. Fitzgerald, Lih-Ling Lin, Suzana Marusic, Vincent Ling, J. Perry Hall, Nancy L. Stedman, Zhaozhao Jiang, Paresh Thakker, Mark Ryan, Erica Marchlik, Wen Kuang, Richard Pfeifer, Stephen C. Benoit, Nadege Goutagny, Thaddeus Carlson

Publikováno v: Journal of Leukocyte Biology. 88:1171-1180

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues, altered circulating immune cell compartments, and increased susceptibility to LPS-induced lethality. TBK1 is critical for immunity against microbial pathogens that activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2beab5dc81f0829fdc1fe59e4ebc328c
https://doi.org/10.1189/jlb.0210071

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