Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Erica L. Lowthers"'
Publikováno v:
Experimental Cell Research. 313:3446-3458
The chemokine receptor CXCR4 plays a key role in the metastasis of colorectal cancer and its growth at metastatic sites. Here, we have investigated the mechanisms by which CXCR4 on cancer cells might be regulated by eicosanoids present within the col
Autor:
Paul A. Spagnuolo, Erica L. Lowthers, Cynthia L. Richard, Jonathan Blay, Dagmar M. Hajducek, Murray J. Cutler
Publikováno v:
BMC Cancer
Background Recurrence of colorectal cancer (CRC) may arise due to the persistence of drug-resistant and cancer-initiating cells that survive exposure to chemotherapy. Proteins responsible for this recurrence include the chemokine receptor CXCR4, whic
Autor:
Paul A. Spagnuolo, Dagmar M. Hajducek, Erica L. Lowthers, Cynthia L. Richard, Jonathan Blay, Murray J. Cutler
Publikováno v:
Clinical Cancer Research. 21:B06-B06
Conventional chemotherapy eliminates the bulk of colorectal cancer (CRC) following surgery. However, recurrence may occur due to the persistence of drug-resistant and cancer-initiating cells that survive exposure to the chemotherapeutic agents. The r
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 39(8-9)
The cytotoxic activity of short-chain (C(2)) ceramide was evaluated in human intestinal carcinoma cells grown as multicellular tumor spheroids versus the same cells cultured as monolayers under closely comparable conditions. A decrease in cell number