Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Erica L. Eggers"'
Autor:
Colin R. Zamecnik, Gavin M. Sowa, Ahmed Abdelhak, Ravi Dandekar, Rebecca D. Bair, Kristen J. Wade, Christopher M. Bartley, Asritha Tubati, Refujia Gomez, Camille Fouassier, Chloe Gerungan, Jessica Alexander, Anne E. Wapniarski, Rita P. Loudermilk, Erica L. Eggers, Kelsey C. Zorn, Kirtana Ananth, Nora Jabassini, Sabrina A. Mann, Nicholas R. Ragan, Adam Santaniello, Roland G. Henry, Sergio E. Baranzini, Scott S. Zamvil, Riley M. Bove, Chu-Yueh Guo, Jeffrey M. Gelfand, Richard Cuneo, H.-Christian von Büdingen, Jorge R. Oksenberg, Bruce AC Cree, Jill A. Hollenbach, Ari J. Green, Stephen L. Hauser, Mitchell T. Wallin, Joseph L. DeRisi, Michael R. Wilson
Publikováno v:
medRxiv
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. Here, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac96b2bbc77aa7d1a7a685cce7b501a
https://europepmc.org/articles/PMC10187343/
https://europepmc.org/articles/PMC10187343/
Autor:
S. Jake Gonzales, Erica L. Eggers, Isaac Ssewanyana, Evelien M. Bunnik, Sebastiaan Bol, Raphael A. Reyes, Ashley E. Braddom, Bryan Greenhouse, Richard T. Sullivan
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-15 (2021)
Malaria Journal
Malaria Journal
Background Chronic and frequently recurring infectious diseases, such as malaria, are associated with expanded populations of atypical memory B cells (MBCs). These cells are different from classical MBCs by the lack of surface markers CD21 and CD27 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018fd2fe9d716fe0fa3c18796e5ce859
https://doaj.org/article/7854bd5a269c4627924f579267bd1b30
https://doaj.org/article/7854bd5a269c4627924f579267bd1b30
Autor:
H.-Christian von Büdingen, Ann Herman, Kit Wong, Ivan Peng, Antje Bischof, Alexander R. Abbas, James Lee, Michael J. Townsend, Tracy Staton, Meire Bremer, Surinder Jeet, A. Francesca Setiadi, Erica L. Eggers, Jason DeVoss
Publikováno v:
Journal of neuroimmunology. 332
IL-17 has been implicated in the pathogenesis of multiple sclerosis (MS). Here, we show that blockade of IL-17A, but not IL-17F, attenuated experimental autoimmune encephalomyelitis (EAE). We further show that IL-17A levels were elevated in the CSF o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2e0737efb52ec96d5d72092dae570a
https://pubmed.ncbi.nlm.nih.gov/31034962
https://pubmed.ncbi.nlm.nih.gov/31034962
Autor:
Martin S. Weber, William Harkin, Natalie S. Pierson, Hao Wu, Ariele L. Greenfield, Ravi Dandekar, Michael R. Wilson, Stephen L. Hauser, H.-Christian von Büdingen, Sarah Laurent, Bruce A.C. Cree, Antje Bischof, Erica L. Eggers, Akshaya Ramesh, Roland G. Henry
B-cells are key contributors to chronic autoimmune pathology in multiple sclerosis (MS). Clonally related B-cells exist in the cerebrospinal fluid (CSF), meninges, and central nervous system (CNS) parenchyma of MS patients. Longitudinally stable CSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96ffc73d8d1bc98f6a0672c9f439a10
Autor:
James Landefeld, Rita P. Loudermilk, Michael R. Wilson, Sergio E. Baranzini, Ryan Baumann, Ucsf Ms-Epic Team, Elva Kogl, Stephen L. Hauser, Julia Dyckow, Lohith Madireddy, Sneha Singh, Erica L. Eggers, Kicheol Kim, Bruce A.C. Cree, Lucas Schirmer, Stacy J. Caillier, Anne-Katrin Pröbstel
Publikováno v:
Brain
Multiple sclerosis is an autoimmune disease of the CNS in which both genetic and environmental factors are involved. Genome-wide association studies revealed more than 200 risk loci, most of which harbour genes primarily expressed in immune cells. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1adfd8421f1d3f139ca69d28e3f59e
https://doi.org/10.1038/s41582-021-00460-5
https://doi.org/10.1038/s41582-021-00460-5
Autor:
Max Kazer, Michael R. Wilson, Natalie S. Pierson, Stanislas Demuth, H.-Christian von Büdingen, Aya Abounasr, Stephen L. Hauser, Roland G. Henry, Brady Michel, Hao Wu, Carolyn Bevan, Erica L. Eggers, Ariele L. Greenfield, Sheng-zhi Wang, Bruce A.C. Cree, Elizabeth G. Leitner, Antje Bischof
Publikováno v:
JCI insight, vol 2, iss 22
A role of B cells in multiple sclerosis (MS) is well established, but there is limited understanding of their involvement during active disease. Here, we examined cerebrospinal fluid (CSF) and peripheral blood (PB) B cells in treatment-naive patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c69cff79b3246855f12ab8f94b1de3
https://escholarship.org/uc/item/62h2h91b
https://escholarship.org/uc/item/62h2h91b
Autor:
Sheng-zhi Wang, Antje Bischof, Roland G. Henry, H.-Christian von Büdingen, Stephen L. Hauser, Bruce A.C. Cree, Erica L. Eggers, Carolyn Bevan
Publikováno v:
Annals of Clinical and Translational Neurology
A patient with relapsing multiple sclerosis (RMS) was treated with a standard immunomodulatory therapy, but due to ongoing disease activity was switched to rituximab. Relapses ceased, but secondary progressive MS (SPMS) eventually appeared, associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e707fec090626944683da4c07f7694b
https://pubmed.ncbi.nlm.nih.gov/28078314
https://pubmed.ncbi.nlm.nih.gov/28078314
Autor:
Sohn G. Kim, Helen Impey, Dong Sung An, Irvin S. Y. Chen, Bryan P. Burke, Geoff Symonds, Emily L. Lowe, Ruth Cortado, Erica L. Eggers, Maureen Boyd, Naomi Keech, Dimitrios N. Vatakis, Scott G. Kitchen, Gene-Errol Ringpis, Maria V. Carroll, Valerie Rezek, Jeffrey S. Bartlett, Anna Sahakyan, Gregory Bristol, Breton Louis Randall, Joanna Camba Colón, Joshua Boyer, Bernard Levin, Saki Shimizu, Jane Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Burke, BP; Levin, BR; Zhang, J; Sahakyan, A; Boyer, J; Carroll, MV; et al.(2015). Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector. MOLECULAR THERAPY-NUCLEIC ACIDS, 4. doi: 10.1038/mtna.2015.10. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6t58k9gs
Molecular therapy. Nucleic acids, vol 4, iss 4
Burke, BP; Levin, BR; Zhang, J; Sahakyan, A; Boyer, J; Carroll, MV; et al.(2015). Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector. MOLECULAR THERAPY-NUCLEIC ACIDS, 4. doi: 10.1038/mtna.2015.10. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6t58k9gs
Molecular therapy. Nucleic acids, vol 4, iss 4
We described earlier a dual-combination anti-HIV type 1 (HIV-1) lentiviral vector (LVsh5/C46) that downregulates CCR5 expression of transduced cells via RNAi and inhibits HIV-1 fusion via cell surface expression of cell membrane-anchored C46 antivira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3195f4243f1b3769b7f7359b4d9860c9
http://www.sciencedirect.com/science/article/pii/S2162253116300221
http://www.sciencedirect.com/science/article/pii/S2162253116300221
Publikováno v:
Humanized Mice for HIV Research ISBN: 9781493916542
Genetic engineering of hematopoietic stem/progenitor cell (HSPCs) produces stably protected HSPCs that can continuously create progeny capable of resisting HIV infection. Anti-HIV HSPC therapy strategies hold great promise to achieve stable control o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ac9d8f48c1887662725c6c587930a0
https://doi.org/10.1007/978-1-4939-1655-9_33
https://doi.org/10.1007/978-1-4939-1655-9_33