Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Erica Kimber"'
Autor:
Michael J Kraakman, Christoph Garbers, Tamara L Allen, Darren C. Henstridge, Mark A. Febbraio, Helene L. Kammoun, Lena Cron, Amanda E. Brandon, Casey L. Egan, Emma Estevez, James Sligar, Paul A. Baldock, Clinton R. Bruce, Guy Y. Krippner, Trevor J. Biden, Damien J. Keating, Emily W. Sun, Gregory J. Cooney, Martin Pal, Stefan Rose-John, Timothy E. Adams, Peter J. Meikle, Richard L. Young, Natalie A. Mellet, Greg M. Kowalski, Joachim Grötzinger, Michael A. Cowley, Laurie L. Baggio, Steve Risis, Liam O’Reilly, Robert S. Lee, Kevin I. Watt, Paul Gregorevic, Erica Kimber, Maria Findeisen, Christine Yang, Le May Thai, Daniel J. Drucker
Publikováno v:
Nature. 574(7776)
The gp130 receptor cytokines IL-6 and CNTF improve metabolic homeostasis but have limited therapeutic use for the treatment of type 2 diabetes. Accordingly, we engineered the gp130 ligand IC7Fc, in which one gp130-binding site is removed from IL-6 an
Autor:
Mark A. Febbraio, Erica Kimber, Timothy E. Adams, Casey L. Egan, Maria Findeisen, Stefan Rose-John
Publikováno v:
Obesity Research & Clinical Practice. 13:281-282
Autor:
Bing M. Liao, Peter J. Meikle, Dale Hancock, Gregory J. Cooney, Erica Kimber, Trevor J. Biden, Saskia Reibe, Mark A. Febbraio, Katy Raddatz, Sophie A. McManus, Amanda E. Brandon, Benjamin L. Parker, Liam O’Reilly, Barbara Diakanastasis, A. Gabrielle van der Kraan, David E. James, Darren C. Henstridge, Carsten Schmitz-Peiffer
Publikováno v:
Cell Metabolism. 29:183-191.e7
Protein kinase C epsilon (PKCɛ) activation in the liver is proposed to inhibit insulin action through phosphorylation of the insulin receptor. Here, however, we demonstrated that global, but not liver-specific, deletion of PKCɛ in mice protected ag