Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Erica J. Young"'
Publikováno v:
J Neurosci
Nonmuscle myosin II inhibition (NMIIi) in the basolateral amygdala (BLA), but not dorsal hippocampus (CA1), selectively disrupts memories associated with methamphetamine (METH) days after learning, without retrieval. However, the molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e59bf5cf11c1d94d4dc26e1d4f88c7
https://doi.org/10.1523/jneurosci.2182-19.2020
https://doi.org/10.1523/jneurosci.2182-19.2020
Autor:
Laszlo, Radnai, Matthew, Surman, Madalyn, Hafenbreidel, Erica J, Young, Rebecca F, Stremel, Li, Lin, Bilel, Bdiri, Paolo, Pasetto, Xiaomin, Jin, Mackenzie, Geedy, Joni-Rae, Partridge, Aagam, Patel, Michael, Conlon, James R, Sellers, Michael D, Cameron, Gavin, Rumbaugh, Patrick R, Griffin, Theodore M, Kamenecka, Courtney A, Miller
Publikováno v:
ACS chemical biology. 16(11)
Myosin IIs, actin-based motors that utilize the chemical energy of adenosine 5'-triphosphate (ATP) to generate force, have potential as therapeutic targets. Their heavy chains differentiate the family into muscle (skeletal [SkMII], cardiac, smooth) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83946f8459880168dbfa6f055d58c650
https://pubmed.ncbi.nlm.nih.gov/34558887
https://pubmed.ncbi.nlm.nih.gov/34558887
Autor:
László Radnai, Theodore M. Kamenecka, Matthew David Surman, James R. Sellers, Gavin Rumbaugh, Michael D. Cameron, Xiaomin Jin, Aagam Patel, Paolo Pasetto, Mackenzie Geedy, Rebecca F Stremel, Michael Conlon, Madalyn Hafenbreidel, Courtney A. Miller, Patrick R. Griffin, Erica J. Young, Joni-Rae Partridge, Li Lin
Myosin IIs, actin-based motors that utilize the chemical energy of ATP to generate force, have potential as therapeutic targets. Their heavy chains differentiate the family into muscle (skeletal [SkMII], cardiac, smooth) and nonmuscle myosin IIs. Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e9cecf019baf1490f144dbdfacd638d
https://doi.org/10.1101/2020.07.28.225383
https://doi.org/10.1101/2020.07.28.225383
Nonmuscle myosin II inhibition disrupts methamphetamine-associated memory in females and adolescents
Publikováno v:
Neurobiology of Learning and Memory. 139:109-116
Memories associated with drug use can trigger strong motivation for the drug, which increases relapse vulnerability in substance use disorder (SUD). Currently there are no treatments for relapse to abuse of psychostimulants, such as methamphetamine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4912935c15c777689afb34b3e28ecc
https://doi.org/10.1016/j.nlm.2017.01.001
https://doi.org/10.1016/j.nlm.2017.01.001
Publikováno v:
Learning & Memory. 24:70-75
Depolymerizing actin in the amygdala through nonmuscle myosin II inhibition (NMIIi) produces a selective, lasting, and retrieval-independent disruption of the storage of methamphetamine-associated memories. Here we report a similar disruption of memo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1c74d1b12fd4054a18379ee46171b8
https://doi.org/10.1101/lm.043976.116
https://doi.org/10.1101/lm.043976.116
Nonmuscle myosin II inhibition (NMIIi) in the basolateral amygdala (BLA) selectively disrupts memories associated with methamphetamine (METH) days after learning, without retrieval. However, the molecular mechanisms underlying this selective vulnerab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c56218c7d0990337e15b8c74636178
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 25(9)
Using pharmacologic and genetic approaches targeting actin or the actin-driving molecular motor, nonmuscle myosin II (NMII), we previously discovered an immediate, retrieval-independent, and long-lasting disruption of methamphetamine- (METH-) and amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4282317570f94883d6379730834073d3
https://pubmed.ncbi.nlm.nih.gov/30115760
https://pubmed.ncbi.nlm.nih.gov/30115760
Autor:
Courtney A. Miller, Erica J. Young, Li Lin, Stephanie E. Sillivan, Gavin Rumbaugh, Michael D. Cameron, Sherri B. Briggs, Ashley M. Blouin
Publikováno v:
Molecular Psychiatry. 21:615-623
Memories associated with drug use increase vulnerability to relapse in substance use disorder (SUD) and there are no pharmacotherapies for the prevention of relapse. Previously, we reported a promising finding that storage of memories associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8d2050b5d47cf55e18ad955fc0bfe1
https://doi.org/10.1038/mp.2015.103
https://doi.org/10.1038/mp.2015.103
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 14:731-737
A high rate of relapse is a defining characteristic of substance use disorder for which few treatments are available. Exposure to environmental cues associated with previous drug use can elicit relapse by causing the involuntary retrieval of deeply e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f9bb2188295dd793ff5f61b545b4c8
https://doi.org/10.2174/1871527314666150529145531
https://doi.org/10.2174/1871527314666150529145531
Autor:
Erica M. Griggs, Gavin Rumbaugh, Irma F. Takács, Courtney A. Miller, Thomas Vaissière, Argel Aguilar-Valles, Mikael A. Mikaelsson, Erica J. Young
Publikováno v:
Biological Psychiatry. 76:57-65
Background Memories associated with drugs of abuse, such as methamphetamine (METH), increase relapse vulnerability to substance use disorder by triggering craving. The nucleus accumbens (NAc) is essential to these drug-associated memories, but underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a478d675e0e5c909891322b3ec1b34
https://doi.org/10.1016/j.biopsych.2013.09.014
https://doi.org/10.1016/j.biopsych.2013.09.014