Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erica Ferrini"'
Autor:
Davide Buseghin, Andrea Grandi, Erica Ferrini, Gino Villetti, Roberta Ciccimarra, Nicola Sverzellati, Andrea Aliverti, Francesca Pennati, Franco Fabio Stellari
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Idiopathic Pulmonary Fibrosis (IPF), prevalently affecting individuals over 60 years of age, has been mainly studied in young mouse models. The limited efficacy of current treatments underscores the need for animal models that bet
Externí odkaz:
https://doaj.org/article/202c88ebbc6146dc8d65c64f107a171f
Autor:
Martina Buccardi, Andrea Grandi, Erica Ferrini, Davide Buseghin, Gino Villetti, Maurizio Civelli, Nicola Sverzellati, Andrea Aliverti, Francesca Pennati, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a debilitating and fatal lung disease characterized by the excessive formation of scar tissue and decline of lung function. Despite extensive research, only two FDA-approved drugs exist for IPF, with li
Externí odkaz:
https://doaj.org/article/1d01f998850d481ab5eb44d736a8a6c0
Autor:
Francesca Pennati, Sasha Belenkov, Martina Buccardi, Erica Ferrini, Nicola Sverzellati, Gino Villetti, Andrea Aliverti, Franco Fabio Stellari
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109262- (2024)
Summary: Micro-computed tomography derived functional biomarkers used in lung disease research can significantly complement end-stage histomorphometric measures while also allowing for longitudinal studies. However, no approach for visualizing lung d
Externí odkaz:
https://doaj.org/article/c8f217f1ff144497bccbfc1f9f7483b4
Autor:
Martina Buccardi, Erica Ferrini, Francesca Pennati, Elena Vincenzi, Roberta Eufrasia Ledda, Andrea Grandi, Davide Buseghin, Gino Villetti, Nicola Sverzellati, Andrea Aliverti, Franco Fabio Stellari
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Micro-computed tomography (µCT)-based imaging plays a key role in monitoring disease progression and response to candidate drugs in various animal models of human disease, but manual image processing is still highly time-consuming and prone
Externí odkaz:
https://doaj.org/article/f5a183803e474fc89405544c8908d010
Autor:
Francesca Pennati, Ludovica Leo, Erica Ferrini, Nicola Sverzellati, Davide Bernardi, Franco Fabio Stellari, Andrea Aliverti
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Experimental in-vivo animal models are key tools to investigate the pathogenesis of lung disease and to discover new therapeutics. Histopathological and biochemical investigations of explanted lung tissue are currently considered the gold st
Externí odkaz:
https://doaj.org/article/8516d26d892a43dfb16110a9f7dcb884
Autor:
Elena Vincenzi, Alice Fantazzini, Curzio Basso, Annalisa Barla, Francesca Odone, Ludovica Leo, Laura Mecozzi, Martina Mambrini, Erica Ferrini, Nicola Sverzellati, Franco Fabio Stellari
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Idiopathic pulmonary fibrosis, the archetype of pulmonary fibrosis (PF), is a chronic lung disease of a poor prognosis, characterized by progressively worsening of lung function. Although histology is still the gold standard for PF assessmen
Externí odkaz:
https://doaj.org/article/da3b3e43dcf74a52b2ccafccd058f3fb
Autor:
Martina Mambrini, Laura Mecozzi, Erica Ferrini, Ludovica Leo, Davide Bernardi, Andrea Grandi, Nicola Sverzellati, Livia Ruffini, Mario Silva, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Micro-computed tomography (CT) imaging provides densitometric and functional assessment of lung diseases in animal models, playing a key role either in understanding disease progression or in drug discovery studies. The generation of reliabl
Externí odkaz:
https://doaj.org/article/dd01d3fe6e6948b5b4edccfea9b54f40
Autor:
Francesca Ravanetti, Erica Ferrini, Luisa Ragionieri, Zahra Khalajzeyqami, Maria Nicastro, Yanto Ridwan, Alex Kleinjan, Gino Villetti, Andrea Grandi, Franco Fabio Stellari
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Systemic sclerosis (SSc) is an autoimmune disease characterized by an excessive production and accumulation of collagen in the skin and internal organs often associated with interstitial lung disease (ILD). Its pathogenetic mechanisms are un
Externí odkaz:
https://doaj.org/article/c97189aa45ba426ca1dc74f514bdf894
Autor:
Zahra Khalajzeyqami, Andrea Grandi, Erica Ferrini, Francesca Ravanetti, Ludovica Leo, Martina Mambrini, Luciana Giardino, Gino Villetti, Franco Fabio Stellari
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0270005 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with no curative pharmacological treatment. The most used animal model of IPF for anti-fibrotic drug screening is bleomycin (BLM)-induced lung fibrosis. However, several issues have been re
Externí odkaz:
https://doaj.org/article/75a10868de4448b087ae57fe84d962a1
Autor:
Erica Ferrini, Fabio Franco Stellari, Valentina Franceschi, Francesca Macchi, Luca Russo, Alba Murgia, Giulia Grisendi, Gino Villetti, Massimo Dominici, Gaetano Donofrio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal/stem cells (MSCs) are a fibroblast-like cell population with high regenerative potential that can be isolated from many different tissues. Several data suggest MSCs as a therapeutic tool capable of migrating to a site of injury an
Externí odkaz:
https://doaj.org/article/280c6cd9e92049a4bdcb9a9dd4543c6d