Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Erica Bresciani"'
Autor:
Juan P. García-López, Alexandre Grimaldi, Zelin Chen, Claudio Meneses, Karina Bravo-Tello, Erica Bresciani, Alvaro Banderas, Shawn M. Burgess, Pedro P. Hernández, Carmen G. Feijoo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The current view of hematopoiesis considers leukocytes on a continuum with distinct developmental origins, and which exert non-overlapping functions. However, there is less known about the function and phenotype of ontogenetically distinct n
Externí odkaz:
https://doaj.org/article/9a3a9a1966be498da59fdd80edcd5d65
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Genome editing using CRISPR/Cas9 has become a powerful tool in zebrafish to generate targeted gene knockouts models. However, its use for targeted knock-in remains challenging due to inefficient homology directed repair (HDR) path
Externí odkaz:
https://doaj.org/article/3832feaabff945a09e26b9f89b2e9c43
Autor:
Jason W. Sinclair, David R. Hoying, Erica Bresciani, Damian Dalle Nogare, Carli D. Needle, Alexandra Berger, Weiwei Wu, Kevin Bishop, Abdel G. Elkahloun, Ajay Chitnis, Paul Liu, Shawn M. Burgess
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Throughout their lifetime, fish maintain a high capacity for regenerating complex tissues after injury. We utilized a larval tail regeneration assay in the zebrafish Danio rerio, which serves as an ideal model of appendage regeneration due t
Externí odkaz:
https://doaj.org/article/5119c383031f466eb2e13637fd267373
Autor:
Juan P. García-López, Alexandre Grimaldi, Zelin Chen, Claudio Meneses, Karina Bravo-Tello, Erica Bresciani, Alvaro Banderas, Shawn M. Burgess, Pedro P. Hernández, Carmen G. Feijoo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4f784bfdcd114ea9ac2fadc217911f13
Publikováno v:
MethodsX, Vol 5, Iss , Pp 1287-1290 (2018)
Zebrafish (Danio rerio) has emerged as a powerful animal model to study developmental processes and human diseases. The introduction of CRISPR/Cas9 as a genome editing tool allowed the generation of genetic mutants with high-throughput (Varshney et a
Externí odkaz:
https://doaj.org/article/1c16aeccea134c6aab129e5863eac1ed
Autor:
Mara Mazzola, Gianluca Deflorian, Alex Pezzotta, Laura Ferrari, Grazia Fazio, Erica Bresciani, Claudia Saitta, Luca Ferrari, Monica Fumagalli, Matteo Parma, Federica Marasca, Beatrice Bodega, Paola Riva, Franco Cotelli, Andrea Biondi, Anna Marozzi, Gianni Cazzaniga, Anna Pistocchi
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
The nucleophosmin 1 gene (NPM1) is the most frequently mutated gene in acute myeloid leukemia. Notably, NPM1 mutations are always accompanied by additional mutations such as those in cohesin genes RAD21, SMC1A, SMC3, and STAG2 but not in the cohesin
Externí odkaz:
https://doaj.org/article/2a860a51750740278fb6788ba7cc49e3
Autor:
Aniket V Gore, Brett Athans, James R Iben, Kristin Johnson, Valya Russanova, Daniel Castranova, Van N Pham, Matthew G Butler, Lisa Williams-Simons, James T Nichols, Erica Bresciani, Bejamin Feldman, Charles B Kimmel, Paul P Liu, Brant M Weinstein
Publikováno v:
eLife, Vol 5 (2016)
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications are thought to contribute to maintain these cell fates. Our understanding of how genetic and epigenetic modes of regulation
Externí odkaz:
https://doaj.org/article/d49e94f6588e42b886215463aa573ada
Autor:
Silvia Carra, Efrem Foglia, Solei Cermenati, Erica Bresciani, Costanza Giampietro, Carla Lora Lamia, Elisabetta Dejana, Monica Beltrame, Franco Cotelli
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51245 (2012)
BACKGROUND: Endothelial cell junctions control blood vessel permeability. Altered permeability can be associated with vascular fragility that leads to vessel weakness and haemorrhage formation. In vivo studies on the function of genes involved in the
Externí odkaz:
https://doaj.org/article/6431f449ff574ef6a73227714e31aac1
Autor:
Erica Bresciani, Stefano Confalonieri, Solei Cermenati, Simona Cimbro, Efrem Foglia, Monica Beltrame, Pier Paolo Di Fiore, Franco Cotelli
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14296 (2010)
BACKGROUND:Notch signaling is an evolutionarily conserved regulatory circuitry implicated in cell fate determination in various developmental processes including hematopoietic stem cell self-renewal and differentiation of blood lineages. Known endoge
Externí odkaz:
https://doaj.org/article/ac56c0ea022048c78118c51f5e4d58b4
Autor:
Alexandra U. Zezulin, Darwin Ye, Elizabeth Howell, Daniel Yen, Erica Bresciani, Jamie Diemer, Jian-gang Ren, Mohd Hafiz Ahmad, Lucio H. Castilla, Ivo P. Touw, Andy J. Minn, Wei Tong, P. Paul Liu, Kai Tan, Wenbao Yu, Nancy A. Speck
Publikováno v:
bioRxiv
The transcription factor RUNX1 is mutated in familial platelet disorder with associated myeloid malignancies (FPDMM) and in sporadic myelodysplastic syndrome and leukemia. RUNX1 regulates inflammation in multiple cell types. Here we show that RUNX1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9736b448f8f77bc7199a13137265e89e
https://doi.org/10.1101/2023.01.27.525911
https://doi.org/10.1101/2023.01.27.525911