Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Erica Bello"'
Autor:
Clara Alsinet, Maria Nascimento Primo, Valentina Lorenzi, Erica Bello, Iva Kelava, Carla P. Jones, Roser Vilarrasa-Blasi, Carmen Sancho-Serra, Andrew J. Knights, Jong-Eun Park, Beata S. Wyspianska, Gosia Trynka, David F. Tough, Andrew Bassett, Daniel J. Gaffney, Damiana Alvarez-Errico, Roser Vento-Tormo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The myeloid lineage is central to homeostasis and immunity. The authors provide an atlas of human iPSC-to-myeloid cell differentiation and demonstrate that the in vitro system recapitulates yolk sac differentiation, opening new avenues to human myelo
Externí odkaz:
https://doaj.org/article/ff14b8d69b054e38a5e0e2b1247d1b45
Autor:
Erica Bello, Jonathan Kerry, Shalini Singh, Bon Ham Yip, Rajko Kušec, Sally Killick, Sophie Raynaud, Jacqueline Boultwood, Andrea Pellagatti
Publikováno v:
Haematologica, Vol 103, Iss 11 (2018)
Externí odkaz:
https://doaj.org/article/8f0252643641445083e60129c8913004
Autor:
Clara Alsinet, Maria Nascimento Primo, Valentina Lorenzi, Erica Bello, Iva Kelava, Carla P. Jones, Roser Vilarrasa-Blasi, Carmen Sancho-Serra, Andrew J. Knights, Jong-Eun Park, Beata S. Wyspianska, Gosia Trynka, David F. Tough, Andrew Bassett, Daniel J. Gaffney, Damiana Alvarez-Errico, Roser Vento-Tormo
Publikováno v:
Nature communications. 13(1)
We thank the Cellular Genetics wet lab support team, Cellular Genetics IT team, Sanger Sequencing operations and Sanger Cytometry Core facility for their essential help. We thank the Gene Editing team for providing iPSC knock-out lines. We would also
Autor:
Sarah Cooper, Adam Young, Pedro Beltrao, Daniel J. Gaffney, Robin J.M. Franklin, Natsuhiko Kumasaka, K. Estrada, Toby Johnson, Inigo Barrio-Hernandez, Jeremy Schwartzentruber, Andrew R. Bassett, Jimmy Z. Liu, Erica Bello
Publikováno v:
Nature genetics
Genome-wide association studies (GWAS) have discovered numerous genomic loci associated with Alzheimer’s disease (AD), yet the causal genes and variants remain incompletely identified. We performed an updated genome-wide AD meta-analysis, which ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5bb5d18125c6ba0cee730013bb74d1
https://www.repository.cam.ac.uk/handle/1810/314768
https://www.repository.cam.ac.uk/handle/1810/314768
Autor:
Daniel J. Gaffney, Natsuhiko Kumasaka, Erica Bello, Andrew R. Bassett, Jeremy Schwartzentruber, Inigo Barrio-Hernandez, Karol Estrada, Sarah Cooper, Toby Johnson, Jimmy Z. Liu, Pedro Beltrao
Genome-wide association studies (GWAS) have discovered numerous genomic loci associated with Alzheimer’s disease (AD), yet the causal genes and variants remain incompletely identified. We performed an updated genome-wide AD meta-analysis, which ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a421d09c2192584e1628104572bb32b3
https://doi.org/10.1101/2020.01.22.20018424
https://doi.org/10.1101/2020.01.22.20018424
Autor:
Erica Bello, Daniel J. Gaffney, Jimmy Z. Liu, Sarah Cooper, Jeremy Schwartzentruber, K. Estrada, Pedro Beltrao, Adam Young, Inigo Barrio-Hernandez, Toby Johnson, Andrew R. Bassett, Robin J.M. Franklin, Natsuhiko Kumasaka
Publikováno v:
Nature Genetics. 53:585-586
Publikováno v:
Nucleic Acids Research
Genome-wide association studies (GWAS) have identified numerous genetic loci underlying human diseases, but a fundamental challenge remains to accurately identify the underlying causal genes and variants. Here, we describe an arrayed CRISPR screening
Autor:
Amit Verma, Shanisha Gordon, Anna Schuh, Swagata Roy, Yiting Yu, Bon Ham Yip, Erica Bello, Jacqueline Shaw, Andrea Pellagatti, L Scifo, Simona Valletta, Tudor A. Fulga, Jacqueline Boultwood, Hamid Dolatshad, Matthias Bartenstein
Publikováno v:
Oncotarget
Recurrent somatic mutations of the epigenetic modifier and tumor suppressor ASXL1 are common in myeloid malignancies, including chronic myeloid leukemia (CML), and are associated with poor clinical outcome. CRISPR/Cas9 has recently emerged as a power
Autor:
Ann McNeill, Karly Olivo, David S. Siegel, Urszula Bendarz, Laura McBride, Madiha Tufail, Palka Anand, Elizabeth Bilotti, David H. Vesole, Erica Bello
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 12:186-190
Thalidomide and lenalidomide, in combination with dexamethasone, provide response rates ranging from 63%-79% after 4 cycles of therapy. Because of toxicities such as neuropathy and myelosuppression for thalidomide and lenalidomide, respectively, dose
Autor:
Aristoteles Giagounidis, Jacqueline Boultwood, Jacqueline Shaw, Andrea Pellagatti, Sally Killick, María José Calasanz, Sophie Raynaud, Pierre Fenaux, Cristina Mecucci, Erica Bello, Rajko Kusec
Publikováno v:
British Journal of Haematology
The myelodysplastic syndromes (MDS) are a heterogeneous group of clonal haematopoietic stem cell (HSC) malignancies characterized by ineffective haematopoiesis and peripheral blood cytopenias (Heaney & Golde, 1999). MDS patients typically have a hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26747b2c342942865d1583fac087284b
https://doi.org/10.1111/bjh.13563
https://doi.org/10.1111/bjh.13563