Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erica B Wilson"'
Autor:
Kelly J. McKelvey, Erica B. Wilson, Susan Short, Alan A. Melcher, Michael Biggs, Connie I. Diakos, Viive M. Howell
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most aggressive adult glioma with a median survival of 14 months. While standard treatments (safe maximal resection, radiation, and temozolomide chemotherapy) have increased the median survival in favorable O(6)-methylguanin
Externí odkaz:
https://doaj.org/article/030135989f354254a2b6784b5c9da99f
Autor:
Michelle Wantoch, Erica B. Wilson, Alastair P. Droop, Sarah L. Phillips, Matt Coffey, Yasser M. El‐Sherbiny, Tim D. Holmes, Alan A. Melcher, Laura F. Wetherill, Graham P. Cook
Publikováno v:
Immunology. 166:104-120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab76b64824716ce570203c30c796cdf7
https://doi.org/10.1111/imm.13453
https://doi.org/10.1111/imm.13453
Autor:
Rebecca J Brownlie, Ruth Kennedy, Erica B Wilson, Maja Milanovic, Claire F Taylor, Dapeng Wang, John Davies, Heather Elizabeth Owston, Emma J Adams, Sophie Stephenson, Rebecca Caeser, Benjamin E Gewurz, Peter V Giannoudis, Claudio Scuoppo, Dennis McGonagle, Daniel J Hodson, Reuben M Tooze, Gina M Doody, Gordon Cook, David R Westhead, Ulf Klein
Publikováno v:
Blood Advances.
Multiple myeloma (MM) shows constitutive activation of canonical and non-canonical nuclear factor-ĸB (NF-ĸB) signaling through genetic mutations or stimuli from the tumour microenvironment (TME). A subset of MM cell lines showed dependency for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd7a05ed7694f34e461dca36e4bc6a7
https://doi.org/10.1182/bloodadvances.2022009044
https://doi.org/10.1182/bloodadvances.2022009044
Autor:
Michelle, Wantoch, Erica B, Wilson, Alastair P, Droop, Sarah L, Phillips, Matt, Coffey, Yasser M, El-Sherbiny, Tim D, Holmes, Alan A, Melcher, Laura F, Wetherill, Graham P, Cook
Publikováno v:
ImmunologyREFERENCES. 166(1)
Natural killer (NK) cells protect against intracellular infection and cancer. These properties are exploited in oncolytic virus (OV) therapy, where antiviral responses enhance anti-tumour immunity. We have analysed the mechanism by which reovirus, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5485407a35c3623ebd1493b05115e89c
https://pubmed.ncbi.nlm.nih.gov/35156714
https://pubmed.ncbi.nlm.nih.gov/35156714
Autor:
Robert Corns, Heiko Wurdak, Helen Close, Alastair Droop, Lucy F. Stead, Erica B. Wilson, Jérémie Nsengimana, Katrina A. Reilly, Alan Melcher, Graham P. Cook, Susan C Short, Ryan K. Mathew, Julia Newton-Bishop
Publikováno v:
Clinical and Experimental Immunology
Summary Glioblastoma (GBM) is an aggressive cancer with a very poor prognosis. Generally viewed as weakly immunogenic, GBM responds poorly to current immunotherapies. To understand this problem more clearly we used a combination of natural killer (NK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd7cee537d368ce92df34dee8a6e800
https://doi.org/10.1111/cei.13403
https://doi.org/10.1111/cei.13403
Autor:
Erica B Wilson, Jehan J El-Jawhari, Abbie L Neilson, Geoffrey D Hall, Alan A Melcher, Josephine L Meade, Graham P Cook
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e22842 (2011)
Immune evasion is now recognized as a key feature of cancer progression. In animal models, the activity of cytotoxic lymphocytes is suppressed in the tumour microenvironment by the immunosuppressive cytokine, Transforming Growth Factor (TGF)-β. Rele
Externí odkaz:
https://doaj.org/article/20d56bb28df2483d9ebfcbba024203d3
Autor:
Susan C Short, Elizabeth S. Appleton, Gemma Migneco, David Taggart, Simon Thomson, Gerard J. Nuovo, Lucy F. Stead, Sergio A. Quezada, Samantha J. Turnbull, Adel Samson, Philip van Hille, Richard G. Vile, Julia V. Cockle, D. Beirne, Fiona Collinson, Fiona Errington-Mais, Karen Scott, Peter Selby, Euan S. Polson, Kevin J. Harrington, Erica B. Wilson, Heiko Wurdak, Martin Fuller, Stephen Griffin, Jill Thompson, Timothy Kottke, Hardev Pandha, Gnanamurthy Sivakumar, Chris Twelves, Ailsa Rose, Christy Ralph, Andrew Furness, Elizabeth Ilett, Robert Corns, Emma West, D. Alan Anthoney, Matthew C. Coffey, Ryan K. Mathew, Alan Melcher
Immune checkpoint inhibitors, including those targeting programmed cell death protein 1 (PD-1), are reshaping cancer therapeutic strategies. Evidence suggests, however, that tumor response and patient survival are determined by tumor programmed death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4899fce1ad145ea879d424f0b5ba845
Autor:
Giles J. Toogood, S L Phillips, Gina B. Scott, Alan Melcher, Yasser M. El-Sherbiny, L F Wetherill, Erica B. Wilson, Tim D. Holmes, Ruth Morgan, R. Adair, Matthew C. Coffey, Graham P. Cook, R. Dave, E V I Black, Karen Scott
Publikováno v:
Clinical and Experimental Immunology. 180:98-107
Summary Human natural killer (NK) cells play an important role in anti-viral immunity. However, studying their activation kinetics during infection is highly problematic. A clinical trial of a therapeutic virus provided an opportunity to study human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1973fb795c67ad6c4fdddacddd30ced
https://doi.org/10.1111/cei.12562
https://doi.org/10.1111/cei.12562
Autor:
Yanjun Zhang, Richard W. Farndale, Peter A. Smethurst, Stephen F. Garner, C. Graham Knight, Willem H. Ouwehand, Lotta Joutsi-Korhonen, Martin J. W. IJsseldijk, Nicola S. Jennings, Marie N. O'Connor, Nicholas A. Watkins, Philip G. de Groot, Ashley M. Buckle, Timothy R. Dafforn, Erica B. Wilson
Publikováno v:
Blood. 103:903-911
Glycoprotein (GP) VI is the major receptor responsible for platelet activation by collagen, but the collagen-binding surface of GPVI is unknown. To address this issue we expressed, from insect cells, the immunoglobulin (Ig)–like ectodomains (residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ae613affbd07b3b65f3387081087bc
https://doi.org/10.1182/blood-2003-01-0308
https://doi.org/10.1182/blood-2003-01-0308
Autor:
D. Huw Davies, Minal T. Kotecha, Razi K. Afghan, Wilson Caparros-Wanderley, Philip Marsh, W. Martin Kast, Erica B. Wilson, Eleni Vasilikopoulou
Publikováno v:
Vaccine. 21:2506-2515
We have examined the induction of anti-tumour immunity in a murine model using a gene vaccine approach to deliver a well defined tumour antigen. The vaccines expressed the human papilloma virus type 16 (HPV 16) E7 oncoprotein, and protection was meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611972adea7bf62ccd6ff131314c95b7
https://doi.org/10.1016/s0264-410x(03)00043-4
https://doi.org/10.1016/s0264-410x(03)00043-4