Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Erica B, Esrick"'
Autor:
Daniel C. De Souza, Nicolas Hebert, Erica B. Esrick, M. Felicia Ciuculescu, Natasha M. Archer, Myriam Armant, Étienne Audureau, Christian Brendel, Giuseppe Di Caprio, Frédéric Galactéros, Donghui Liu, Amanda McCabe, Emily Morris, Ethan Schonbrun, Dillon Williams, David K. Wood, David A. Williams, Pablo Bartolucci, John M. Higgins
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract We previously reported initial clinical results of post-transcriptional gene silencing of BCL11A expression (NCT 03282656) reversing the fetal to adult hemoglobin switch. A goal of this approach is to increase fetal hemoglobin (HbF) expressi
Externí odkaz:
https://doaj.org/article/c27e3b0ea4ac4641bfd4b6b6b60347e0
Autor:
Mary Eapen, Ruta Brazauskas, David A. Williams, Mark C. Walters, Andrew St Martin, Benjamin L. Jacobs, Joseph H. Antin, Kira Bona, Sonali Chaudhury, Victoria H. Coleman-Cowger, Nancy L. DiFronzo, Erica B. Esrick, Joshua J. Field, Courtney D. Fitzhugh, Julie Kanter, Neena Kapoor, Donald B. Kohn, Lakshmanan Krishnamurti, Wendy B. London, Michael A. Pulsipher, Sohel Talib, Alexis A. Thompson, Edmund K. Waller, Ted Wun, Mary M. Horowitz
Publikováno v:
Journal of Clinical Oncology. 41:2227-2237
PURPOSE To report the incidence and risk factors for secondary neoplasm after transplantation for sickle cell disease. METHODS Included are 1,096 transplants for sickle cell disease between 1991 and 2016. There were 22 secondary neoplasms. Types incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f44a9e2a91572d49b8abe6af4b490cb
https://doi.org/10.1200/jco.22.01203
https://doi.org/10.1200/jco.22.01203
Autor:
Erica B. Esrick, Amy Federico, Daniela Abriss, Myriam Armant, Kari Boardman, Christian Brendel, Marioara-Felicia Ciuculescu, Heather Daley, Colleen Dansereau, Augustine Fernandes, Matthew M. Heeney, David G. Justus, Pei-Chi Kao, Annette S. Kim, Donald B. Kohn, Leslie E. Lehmann, Donghui Liu, Wendy B. London, John P Manis, Theodore B. Moore, Emily Morris, Danilo Pellin, Ellen Proeung, Shanna Richard, Gavin D. Roach, Kit L. Shaw, Dayna Terrazas, Shanna L White, David A. Williams
Publikováno v:
Blood. 140:10665-10667
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e828f889a6fcfac4de9b7fcb45370915
https://doi.org/10.1182/blood-2022-169089
https://doi.org/10.1182/blood-2022-169089
Autor:
David G. Justus, Erica B. Esrick, Matthew M. Heeney, Ellen Proeung, Carly Howard, Carlo Brugnara, David A. Williams, John P Manis
Publikováno v:
Blood. 140:5715-5716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49992ab00a1033a02d7bc411a5cd1eaa
https://doi.org/10.1182/blood-2022-170450
https://doi.org/10.1182/blood-2022-170450
Autor:
Olivier Negre, Swaroopa Guda, Christian Brendel, Chad E. Harris, Martin Bentler, Myriam Armant, Melissa Bonner, Erica B. Esrick, John P. Manis, Helene Trebeden-Negre, Axel Schambach, Alla V. Tsytsykova, Danilo Pellin, Michael Rothe, Lauryn Christiansen, Denise Klatt, David A. Williams, Meaghan McGuinness, Daniela Abriss, Geoff Parsons, Gabor Istvan Veres
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 589-600 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
In this work we provide preclinical data to support initiation of a first-in-human trial for sickle cell disease (SCD) using an approach that relies on reversal of the developmental fetal-to-adult hemoglobin switch. Erythroid-specific knockdown of BC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8fc0356964dd1fbe99f38977e8a66a
http://www.sciencedirect.com/science/article/pii/S2329050120300450
http://www.sciencedirect.com/science/article/pii/S2329050120300450
Autor:
Erica B, Esrick, Leslie E, Lehmann, Alessandra, Biffi, Maureen, Achebe, Christian, Brendel, Marioara F, Ciuculescu, Heather, Daley, Brenda, MacKinnon, Emily, Morris, Amy, Federico, Daniela, Abriss, Kari, Boardman, Radia, Khelladi, Kit, Shaw, Helene, Negre, Olivier, Negre, Sarah, Nikiforow, Jerome, Ritz, Sung-Yun, Pai, Wendy B, London, Colleen, Dansereau, Matthew M, Heeney, Myriam, Armant, John P, Manis, David A, Williams
Publikováno v:
The New England journal of medicine. 384(3)
Sickle cell disease is characterized by hemolytic anemia, pain, and progressive organ damage. A high level of erythrocyte fetal hemoglobin (HbF) comprising α- and γ-globins may ameliorate these manifestations by mitigating sickle hemoglobin polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a54e613c2a9b45852cee621477397c3b
https://pubmed.ncbi.nlm.nih.gov/33471981
https://pubmed.ncbi.nlm.nih.gov/33471981
Autor:
Wendy B. London, Heather Daley, David A. Williams, Erica B. Esrick, Francis J. Pierciey, Luca Biasco, Alessandra Biffi, John P. Manis, Matthew M. Heeney, Myriam Armant, Helene Trebeden-Negre, Cristina Baricordi, Mohammed Asmal, Sarah Nikiforow
Publikováno v:
Blood Advances. 2:2505-2512
Novel therapies for sickle cell disease (SCD) based on genetically engineered autologous hematopoietic stem and progenitor cells (HSPCs) are critically dependent on a safe and effective strategy for cell procurement. We sought to assess the safety an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b17f6199b5772a5e58279639d70e3e
https://doi.org/10.1182/bloodadvances.2018016725
https://doi.org/10.1182/bloodadvances.2018016725
Autor:
Erica B. Esrick, Daniel E. Bauer
Publikováno v:
Seminars in Hematology. 55:76-86
After decades with few novel therapeutic options for sickle cell disease (SCD), autologous hematopoietic stem cell (HSC) based genetic therapies including lentiviral gene therapy (GT), and genome editing (GE) now appear imminent. Lentiviral GT has ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b012fad7666dbbdce7b1b6f069ed55b
https://doi.org/10.1053/j.seminhematol.2018.04.014
https://doi.org/10.1053/j.seminhematol.2018.04.014
Autor:
Jacob Bledsoe, Farid Boulad, Annette S. Kim, Laurie E. Cohen, Kaitlyn Ballotti, Elissa M. Furutani, Maggie Malsch, Marcin W. Wlodarski, Amy Hont, María José Ramírez, Erica B. Esrick, Alexis A. Thompson, Edie Weller, Jessica A. Pollard, Alan D. D'Andrea, Jordi Surrallés, Ashley Kuniholm, Ashley Galvin, Towia A. Libermann, Clinton Carroll, Akiko Shimamura, Kun Lu, Lisa A. Moreau, Shanshan Liu, Helge Hartung, Daria V. Babushok, Sei-Gyung K. Sze, Yu Zhou, Myriam Armant, Markus Grompe, Taizo A. Nakano, Timothy S. Olson
Publikováno v:
Blood. 138:1102-1102
Fanconi anemia (FA), a genetic disorder affecting DNA repair, is characterized by bone marrow failure and cancer susceptibility. In FA mouse models, metformin (N,N-dimethylguanide) a biguanide metabolic agent, improves blood counts and delays tumor d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8988dfb489d3161e305f8e7c38eae98c
https://doi.org/10.1182/blood-2021-153598
https://doi.org/10.1182/blood-2021-153598
Autor:
Emily Mitchell, David A. Williams, Grace Boyd, David G. Kent, Myriam Armant, Peter J. Campbell, Alyssa Helene Cull, Michael Spencer Chapman, Marioara Felicia Ciuculescu, Erica B. Esrick
Publikováno v:
Blood. 138:559-559
Recent advances in clonal stem cell tracking strategies have enabled interrogation of unperturbed human hematopoiesis. Whole genome sequencing (WGS) can be used to map the clonal dynamics of hematopoietic stem and progenitor cells (HSPCs) by employin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4abaf944c7bc526672fe0723ed5768d2
https://doi.org/10.1182/blood-2021-152262
https://doi.org/10.1182/blood-2021-152262