Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Erica, De Zan"'
Autor:
Sebastian M.B. Nijman, Farasat Kazmi, In Hwa Um, Ruud G.P.M. van Stiphout, Gareth L. Bond, Mustafa Elshani, Valentina Ferrari, Ruth Plummer, David J. Harrison, Sarah P. Blagden, James Chettle, Mary Kudsy, Michaela Serpi, Stefan Symeonides, Josephine Morris, Hagen Schwenzer, Leticia Campo, Alistair Easton, Erica De Zan
Publikováno v:
Clinical Cancer Research. 27:6500-6513
Purpose: Nucleoside analogues form the backbone of many therapeutic regimens in oncology and require the presence of intracellular enzymes for their activation. A ProTide is comprised of a nucleoside fused to a protective phosphoramidate cap. ProTide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad843422727b7b653fa57850e1f0ab05
https://doi.org/10.1158/1078-0432.ccr-21-1652
https://doi.org/10.1158/1078-0432.ccr-21-1652
Autor:
Corinna A. Kulicke, Erica De Zan, Zeynep Hein, Claudia Gonzalez-Lopez, Swapnil Ghanwat, Natacha Veerapen, Gurdyal S. Besra, Paul Klenerman, John C. Christianson, Sebastian Springer, Sebastian M. Nijman, Vincenzo Cerundolo, Mariolina Salio
The monomorphic antigen-presenting molecule MHC-I-related protein 1 (MR1) presents small molecule metabolites to mucosal-associated invariant T (MAIT) cells. The MR1-MAIT cell axis has been implicated in a variety of infectious and non-communicable d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a868dbed97a502316906fa6fcafedaa1
https://ora.ox.ac.uk/objects/uuid:158ef38c-eed6-40ce-9606-a7dad6b3ee9a
https://ora.ox.ac.uk/objects/uuid:158ef38c-eed6-40ce-9606-a7dad6b3ee9a
Autor:
Taylor S. Cohen, Lisa Öberg, Nisha Kurian, Erica De Zan, Britta Bonn, Petter Svanberg, Engin Baturcam, Gabriel Skogberg, Paul D. Smith, Outi Vaarala, Danen Cunoosamy, Stefan Vollmer
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease. 14:2611-2624
Background Unlike p38 mitogen-activated protein Kinases (MAPK) that has been extensively studied in the context of lung-associated pathologies in COPD, the role of the dual-specificity mitogen-activated protein kinase kinase (MEK1/2) or its downstrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238d5e211e55ca66ace0dbf2e462b1af
https://doi.org/10.2147/copd.s211619
https://doi.org/10.2147/copd.s211619
Autor:
Hagen, Schwenzer, Erica, De Zan, Mustafa, Elshani, Ruud, van Stiphout, Mary, Kudsy, Josephine, Morris, Valentina, Ferrari, In Hwa, Um, James, Chettle, Farasat, Kazmi, Leticia, Campo, Alistair, Easton, Sebastian, Nijman, Michaela, Serpi, Stefan, Symeonides, Ruth, Plummer, David J, Harrison, Gareth, Bond, Sarah P, Blagden
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(23)
Nucleoside analogues form the backbone of many therapeutic regimens in oncology and require the presence of intracellular enzymes for their activation. A ProTide is comprised of a nucleoside fused to a protective phosphoramidate cap. ProTides are eas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1435cbfe29b519bf3ecbc035e215b2d0
https://pubmed.ncbi.nlm.nih.gov/34853073
https://pubmed.ncbi.nlm.nih.gov/34853073
Autor:
Erica de Zan, Ruud van Stiphout, Thijn R. Brummelkamp, Vincent A. Blomen, Sebastian M.B. Nijman, Bianca V. Gapp
Publikováno v:
Science Signaling. 13
Forward genetic screens in mammalian cell lines, such as RNAi and CRISPR-Cas9 screens, have made major contributions to the elucidation of diverse signaling pathways. Here, we exploited human haploid cells as a robust comparative screening platform a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f607778e2474be2807761a4c8b1a4fc
https://doi.org/10.1126/scisignal.aba5665
https://doi.org/10.1126/scisignal.aba5665
Autor:
Erica de Zan, Mustafa Elshani, Michaela Serpi, Valentina Ferrari, Sarah P. Blagden, Sebastian M.B. Nijman, David J. Harrison, Hagen Schwenzer, Mary Kudsy, James Chettle, Josephine Morris, Ruud van Stiphout, Gareth P Bond
Publikováno v:
Cancer Research. 81:931-931
Background: 3'-deoxyadenosine (3'-dA; also known as cordycepin) is a nucleoside analog that has shown potent anti-cancer activity in non-clinical studies but has not been clinically developed because of its vulnerability to rapid degradation by the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff78a50087d1d665d5c0e1344f1ff74
https://doi.org/10.1158/1538-7445.am2021-931
https://doi.org/10.1158/1538-7445.am2021-931
Autor:
Nisha, Kurian, Taylor S, Cohen, Lisa, Öberg, Erica, De Zan, Gabriel, Skogberg, Stefan, Vollmer, Engin, Baturcam, Petter, Svanberg, Britta, Bonn, Paul D, Smith, Outi, Vaarala, Danen M, Cunoosamy
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Background Unlike p38 mitogen-activated protein Kinases (MAPK) that has been extensively studied in the context of lung-associated pathologies in COPD, the role of the dual-specificity mitogen-activated protein kinase kinase (MEK1/2) or its downstrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67d1be01b08097773a85345fd5b55c2d
https://pubmed.ncbi.nlm.nih.gov/32063702
https://pubmed.ncbi.nlm.nih.gov/32063702
Autor:
Hagen Schwenzer, Gareth L. Bond, Cornelia H. de Moor, Ruud G.P.M. van Stiphout, Sebastian M.B. Nijman, Sarah P. Blagden, Erica De Zan
Publikováno v:
Molecular Cancer Therapeutics. 18:A062-A062
Introduction: Cordycepin or 3′-deoxyadenosine is an extract from the fungus Cordyceps sinensis, a popular traditional medicine in the Far East. Although its active metabolite 3′-deoxydenosine 5′-triphosphate (3’dATP) has potent in vitro anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2875395d9f9a2584d0436de79b5416ea
https://doi.org/10.1158/1535-7163.targ-19-a062
https://doi.org/10.1158/1535-7163.targ-19-a062