Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Eric. R. James"'
Autor:
Thomas L. Richie, L.W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei-Chun Chen, Yonas Abebe, Natasha KC, Sumana Chakravarty, David Dolberg, Sara A. Healy, Halimatou Diawara, Mahamadou S. Sissoko, Issaka Sagara, David M. Cook, Judith E. Epstein, Benjamin Mordmüller, Melissa Kapulu, Andrea Kreidenweiss, Blandine Franke-Fayard, Selidji T. Agnandji, María-Silvia A. López Mikue, Matthew B.B. McCall, Laura Steinhardt, Martina Oneko, Ally Olotu, Ashley M. Vaughan, James G. Kublin, Sean C. Murphy, Said Jongo, Marcel Tanner, Sodiomon B. Sirima, Matthew B. Laurens, Claudia Daubenberger, Joana C. Silva, Kirsten E. Lyke, Chris J. Janse, Meta Roestenberg, Robert W. Sauerwein, Salim Abdulla, Alassane Dicko, Stefan H. I. Kappe, B. Kim Lee Sim, Patrick E. Duffy, Peter G. Kremsner, Stephen L. Hoffman
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especi
Externí odkaz:
https://doaj.org/article/64ccc130995e4fbda0570808ef7ca47d
Autor:
Sumana Chakravarty, Melanie J. Shears, Eric R. James, Urvashi Rai, Natasha KC, Solomon Conteh, Lynn E. Lambert, Patrick E. Duffy, Sean C. Murphy, Stephen L. Hoffman
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background Plasmodium falciparum (Pf) sporozoite (SPZ) vaccines are the only candidate malaria vaccines that induce > 90% vaccine efficacy (VE) against controlled human malaria infection and the only malaria vaccines to have achieved reprodu
Externí odkaz:
https://doaj.org/article/4fbb2445f2d24adaba6081405b24db41
Autor:
Eric R. James, Yingda Wen, James Overby, Kristen Pluchino, Shane McTighe, Stephen Matheny, Abraham Eappen, Stephen L. Hoffman, Peter F. Billingsley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract The ability to cryopreserve mosquitoes would revolutionize work on these vectors of major human infectious diseases by conserving stocks, new isolates, lab-bred strains, and transgenic lines that currently require continuous life cycle maint
Externí odkaz:
https://doaj.org/article/e3de1a79dabc4ce6903ee65ecf464176
Autor:
Drissa Coulibaly, Abdoulaye K. Kone, Karim Traore, Amadou Niangaly, Bourema Kouriba, Charles Arama, Amatigue Zeguime, Amagana Dolo, Kirsten E. Lyke, Christopher V. Plowe, Yonas Abebe, Gail E. Potter, Jessie K. Kennedy, Shirley M. Galbiati, Effie Nomicos, Gregory A. Deye, Thomas L. Richie, Eric R. James, Natasha KC, B. Kim Lee Sim, Stephen L. Hoffman, Ogobara K. Doumbo, Mahamadou A. Thera, Matthew B. Laurens
Publikováno v:
EClinicalMedicine, Vol 52, Iss , Pp 101579- (2022)
Summary: Background: Plasmodium falciparum (Pf) Sporozoite (SPZ) Chemoprophylaxis Vaccine (PfSPZ-CVac) involves concurrently administering infectious PfSPZ and malaria drug, often chloroquine (CQ), to kill liver-emerging parasites. PfSPZ-CVac (CQ) pr
Externí odkaz:
https://doaj.org/article/aae8b87f13cf4d72be5ab4f5d3602223
Autor:
Eric R. James, Steve Matheny, James Overby, B. Kim Lee Sim, Abraham G. Eappen, Tao Li, Ming Lin Li, Thomas L. Richie, Sumana Chakravarty, Anusha Gunasekera, Tooba Murshedkar, Peter F. Billingsley, Stephen L. Hoffman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Ionizing radiation (UV, X-ray and ɣ) administered at an appropriate dose to pathogenic organisms can prevent replication while preserving metabolic activity. We have established the GMP process for attenuation by ionizing radiation of the Plasmodium
Externí odkaz:
https://doaj.org/article/f080f2a50f604070b6453d8d6f1822f5
Autor:
Juliana M. Sá, Sarah R. Kaslow, Roberto R. Moraes Barros, Nicholas F. Brazeau, Christian M. Parobek, Dingyin Tao, Rebecca E. Salzman, Tyler J. Gibson, Soundarapandian Velmurugan, Michael A. Krause, Viviana Melendez-Muniz, Whitney A. Kite, Paul K. Han, Richard T. Eastman, Adam Kim, Evan G. Kessler, Yonas Abebe, Eric R. James, Sumana Chakravarty, Sachy Orr-Gonzalez, Lynn E. Lambert, Theresa Engels, Marvin L. Thomas, Pius S. Fasinu, David Serre, Robert W. Gwadz, Larry Walker, Derrick K. DeConti, Jianbing Mu, Jeffrey A. Bailey, B. Kim Lee Sim, Stephen L. Hoffman, Michael P. Fay, Rhoel R. Dinglasan, Jonathan J. Juliano, Thomas E. Wellems
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Here, a cross of Plasmodium vivax malaria parasites links a chloroquine resistance (CQR) phenotype to a 76 kb region of chromosome 1 and greater expression of pvcrt, an ortholog of the Plasmodium falciparum CQR transporter gene.
Externí odkaz:
https://doaj.org/article/d2e5b78b5b7d41ea85f525fdaf910313
Autor:
Sean C Murphy, Gregory A Deye, B Kim Lee Sim, Shirley Galbiati, Jessie K Kennedy, Kristen W Cohen, Sumana Chakravarty, Natasha Kc, Yonas Abebe, Eric R James, James G Kublin, Stephen L Hoffman, Thomas L Richie, Lisa A Jackson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009594 (2021)
PfSPZ-CVac combines 'PfSPZ Challenge', which consists of infectious Plasmodium falciparum sporozoites (PfSPZ), with concurrent antimalarial chemoprophylaxis. In a previously-published PfSPZ-CVac study, three doses of 5.12x104 PfSPZ-CVac given 28 days
Externí odkaz:
https://doaj.org/article/38a4f864bb53428093ed8cf2eb54e63e
Autor:
B. Kim Lee Sim, Minglin Li, Manuel Osorio, Yun Wu, Tint T. Wai, Johnny W. Peterson, Eric R. James, Sumana Chakravarty, Lixin Gao, Rui Xu, Natasha KC, Richard E. Stafford, William S. Lawrence, Linsey A. Yeager, Jennifer E. Peel, Satheesh K. Sivasubramani, Ashok K. Chopra, Svetlana Filippova, Stephen L. Hoffman
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-7 (2017)
Counterterrorism: creating a safe, stable, easily stored anthrax vaccine A vaccine candidate for anthrax infection shows promise for improving preparedness for a biological attack. Bacillus anthracis, the bacterium responsible for anthrax is a top-ti
Externí odkaz:
https://doaj.org/article/e6ed55cb74e9406db34a5f3fb0bf3838
Autor:
Said A. Jongo, Vicente Urbano Nsue Ndong Nchama, L. W. Preston Church, Ally Olotu, Stephen R. Manock, Tobias Schindler, Ali Mtoro, Natasha KC, Orrin Devinsky, Elcin Zan, Ali Hamad, Elizabeth Nyakarungu, Maxmillian Mpina, Anna Deal, José Raso Bijeri, Martin Eka Ondo Mangue, Beltrán Ekua Ntutumu Pasialo, Genaro Nsue Nguema, Matilde Riloha Rivas, Mwajuma Chemba, Kamaka K. Ramadhani, Eric R. James, Thomas C. Stabler, Yonas Abebe, Pouria Riyahi, Elizabeth S. Saverino, Julian Sax, Salome Hosch, Anneth Tumbo, Linda Gondwe, J. Luis Segura, Carlos Cortes Falla, Wonder Philip Phiri, Dianna E. B. Hergott, Guillermo A. García, Carl Maas, Tooba Murshedkar, Peter F. Billingsley, Marcel Tanner, Mitoha Ondo’o Ayekaba, B. Kim Lee Sim, Claudia Daubenberger, Thomas L. Richie, Salim Abdulla, Stephen L. Hoffman
Publikováno v:
The American Journal of Tropical Medicine and Hygiene.
The radiation-attenuated Plasmodium falciparum sporozoites (PfSPZ) Vaccine has demonstrated safety and immunogenicity in 5-month-old to 50-year-old Africans in multiple trials. Except for one, each trial has restricted enrollment to either infants an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f079c3948abc5407bfcf8ad0e1767a
https://doi.org/10.4269/ajtmh.22-0773
https://doi.org/10.4269/ajtmh.22-0773
Autor:
Jacquelyn Lane, Thomas L. Richie, Bourama Kamate, Tooba Murshedkar, Patrick E. Duffy, Fanta Koita, Natasha Kc, Abdoulaye Katile, Ismaila Thera, Agnes Mwakingwe-Omari, Peter F. Billingsley, Stephen L. Hoffman, Anita Manoj, Cheick Oumar Guindo, Amagana Dolo, Merepen A Guindo, Eric R. James, Yacouba Samake, Kelly M. Rausch, Rathy Mohan, Karamoko Niare, B. Kim Lee Sim, Yonas Abebe, Kourane Sissoko, Alemush Imeru, Sara A. Healy, Zonghui Hu, Amadou Niangaly, Ogobara K. Doumbo, Aissatou Bah, Amatigue Zeguime, Mahamadou S Sissoko, Irfan Zaidi
Publikováno v:
Lancet Infect Dis
Summary Background WHO recently approved a partially effective vaccine that reduces clinical malaria in children, but increased vaccine activity is required to pursue malaria elimination. A phase 1 clinical trial was done in Mali, west Africa, to ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83671c7f40083807ec470d4e4da417fc
https://doi.org/10.1016/s1473-3099(21)00332-7
https://doi.org/10.1016/s1473-3099(21)00332-7