Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Eric van Leen"'
Autor:
Liu He, Robbelien Kooistra, Ravi Das, Ellen Oudejans, Eric van Leen, Johannes Ziegler, Sybren Portegies, Bart de Haan, Anna van Regteren Altena, Riccardo Stucchi, AF Maarten Altelaar, Stefan Wieser, Michael Krieg, Casper C Hoogenraad, Martin Harterink
Publikováno v:
eLife, Vol 9 (2020)
The development of a polarized neuron relies on the selective transport of proteins to axons and dendrites. Although it is well known that the microtubule cytoskeleton has a central role in establishing neuronal polarity, how its specific organizatio
Externí odkaz:
https://doaj.org/article/0af7cedb8c114e9684ed3ed0d51fcc6d
Autor:
Rocío Chamorro González, Thomas Conrad, Maja C. Stöber, Robin Xu, Mădălina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brückner, Eric van Leen, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E. Stefanova, King L. Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y. Chang, Hedwig E. Deubzer, Sascha Sauer, Angelika Eggert, Johannes H. Schulte, Roland F. Schwarz, Kerstin Haase, Richard P. Koche, Anton G. Henssen
Extrachromosomal DNAs (ecDNAs) are common in cancer, but many questions about their origin, structural dynamics and impact on intratumor heterogeneity are still unresolved. Here we describe single-cell extrachromosomal circular DNA and transcriptome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc99ed2c6257eafccfbc8313ccf81a41
http://edoc.mdc-berlin.de/23342/2/23342suppl.zip
http://edoc.mdc-berlin.de/23342/2/23342suppl.zip
Publikováno v:
Nature genetics. 54(2)
Extrachromosomal DNA (ecDNA) amplification has been observed in at least 30 different cancer types and is associated with worse patient outcomes. This has been linked to increased oncogene dosage because both oncogenes and associated enhancers can oc
Autor:
Rocio Chamorro Gonzalez, Thomas Conrad, Robin Xu, Madalina Giurgiu, Maja Cwikla, Katharina Kasack, Lotte Brückner, Eric van Leen, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Yi Bei, Karin Schmelz, Sascha Sauer, Angelika Eggert, Johannes H. Schulte, Roland F. Schwarz, Kerstin Haase, Richard P. Koche, Anton G. Henssen
Publikováno v:
Cancer Research. 82:1693-1693
Extrachromosomal DNA circularization is a common event in cancer cells and frequently serves as a vehicle for cancer oncogene amplification. Random segregation of oncogene-containing extrachromosomal circular DNA promotes rapid intercellular heteroge
Author response: Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity
Autor:
A. F. Maarten Altelaar, Stefan Wieser, Bart de Haan, Johannes Ziegler, Martin Harterink, Eric van Leen, Anna van Regteren Altena, Ellen Oudejans, Sybren Portegies, Michael Krieg, Casper C. Hoogenraad, Liu He, Ravi K. Das, Riccardo Stucchi, Robbelien Kooistra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802154ef24d540d8e06f64e88f0f7b8b
https://doi.org/10.7554/elife.55111.sa2
https://doi.org/10.7554/elife.55111.sa2
Autor:
Ravi K. Das, Liu He, Ellen Oudejans, Sybren Portegies, Stefan Wieser, Johannes Ziegler, Anna van Regteren Altena, Riccardo Stucchi, Robbelien Kooistra, A. F. Maarten Altelaar, Casper C. Hoogenraad, Martin Harterink, Bart de Haan, Eric van Leen, Michael Krieg
Publikováno v:
bioRxiv
SUMMARYNeurons are among the most highly polarized cell types. They possess structurally and functionally different processes, axon and dendrites, to mediate information flow through the nervous system. Although it is well known that the microtubule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e792f633f1d82cf46c40b5263f1a7f
https://doi.org/10.1101/783837
https://doi.org/10.1101/783837