Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Eric van Dyck"'
Autor:
Andrea Scafidi, Frida Lind-Holm Mogensen, Eleonora Campus, Alexandros Pailas, Katrin Neumann, Nathalie Legrave, François Bernardin, Sandro L. Pereira, Paul M.A. Antony, Nathalie Nicot, Michel Mittelbronn, Anne Grünewald, Petr V. Nazarov, Aurélie Poli, Eric Van Dyck, Alessandro Michelucci
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37792- (2024)
Background: Epidemiological studies suggest that metformin reduces the risk of developing several types of cancer, including gliomas, and improves the overall survival in cancer patients. Nevertheless, while the effect of metformin on cancer cells ha
Externí odkaz:
https://doaj.org/article/b221e5f5aea84d3ab983d6c758a224c5
Autor:
Eric Van Dyck, Simone P. Niclou, Roland Goldbrunner, Christel C. Herold-Mende, Anthony J. Chalmers, Laurent Vallar, Joerg Felsberg, Guido Reifenberger, Marco Timmer, Rolf Warta, Petr V. Nazarov, Matthieu Gobin
This document details the preliminary differential gene expression analysis carried out using the Köln dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a530a8d9ea59fba62d361db0b20be5f
https://doi.org/10.1158/0008-5472.22422992.v1
https://doi.org/10.1158/0008-5472.22422992.v1
Autor:
Eric Van Dyck, Simone P. Niclou, Roland Goldbrunner, Christel C. Herold-Mende, Anthony J. Chalmers, Laurent Vallar, Joerg Felsberg, Guido Reifenberger, Marco Timmer, Rolf Warta, Petr V. Nazarov, Matthieu Gobin
This document contains Supplementary Table S1, which provides the expression data pertaining to the 27-gene signature and relevant clinical data of the Heidelberg cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25467b3bffad6bda160e6d15ebdb4fed
https://doi.org/10.1158/0008-5472.22422986
https://doi.org/10.1158/0008-5472.22422986
Autor:
Guy Berchem, Eric Van Dyck, Sandrine Pierson, Kris Van Moer, Nicolaas H.C. Brons, Nasséra Aouali, Valérie Palissot, Bassam Janji, Etienne Moussay, Victoria El-Khoury
Clinical trials have shown activity of the isotype-selective histone deacetylase (HDAC) inhibitor MGCD0103 in different hematologic malignancies. There are data to support the use of HDAC inhibitors in association with other cancer therapies. To prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffca00e0f112b3b6f046e2665838a22
https://doi.org/10.1158/1535-7163.c.6532230.v1
https://doi.org/10.1158/1535-7163.c.6532230.v1
Autor:
Eric Van Dyck, Simone P. Niclou, Roland Goldbrunner, Christel C. Herold-Mende, Anthony J. Chalmers, Laurent Vallar, Joerg Felsberg, Guido Reifenberger, Marco Timmer, Rolf Warta, Petr V. Nazarov, Matthieu Gobin
Inevitable tumor recurrence and a poor median survival are frustrating reminders of the inefficacy of our current standard of care for patients with newly diagnosed glioblastoma (GBM), which includes surgery followed by radiotherapy and chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12a4404baa3e65038c24a6372f54666
https://doi.org/10.1158/0008-5472.c.6511391.v1
https://doi.org/10.1158/0008-5472.c.6511391.v1
Autor:
Guy Berchem, Eric Van Dyck, Sandrine Pierson, Kris Van Moer, Nicolaas H.C. Brons, Nasséra Aouali, Valérie Palissot, Bassam Janji, Etienne Moussay, Victoria El-Khoury
Supplementary Data from The Histone Deacetylase Inhibitor MGCD0103 Induces Apoptosis in B-Cell Chronic Lymphocytic Leukemia Cells through a Mitochondria-Mediated Caspase Activation Cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396889c7b2aa046ee70f2cb0cf5a8359
https://doi.org/10.1158/1535-7163.22486080.v1
https://doi.org/10.1158/1535-7163.22486080.v1
Autor:
Eric Van Dyck, Simone P. Niclou, Roland Goldbrunner, Christel C. Herold-Mende, Anthony J. Chalmers, Laurent Vallar, Joerg Felsberg, Guido Reifenberger, Marco Timmer, Rolf Warta, Petr V. Nazarov, Matthieu Gobin
This document contains Supplementary Figures S1-S6 as well as their Legends. Specifically, Fig. S1: characterization of the 52 gene signature; Fig. S2: Validation of the 27 DNA repair and cell cycle gene signature; Fig. S3: Analysis of the Murat coho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5447fb6e0c7fc83360aa25dad83354ae
https://doi.org/10.1158/0008-5472.22422989
https://doi.org/10.1158/0008-5472.22422989
Autor:
Eric Van Dyck, Simone P. Niclou, Roland Goldbrunner, Christel C. Herold-Mende, Anthony J. Chalmers, Laurent Vallar, Joerg Felsberg, Guido Reifenberger, Marco Timmer, Rolf Warta, Petr V. Nazarov, Matthieu Gobin
This document contains Supplementary Table S4, which regroups the differentially expressed genes identified between the G1 and G3 groups of the Wang dataset and the gene ontology terms associated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f7bf2604820960fa6104bab910aec8
https://doi.org/10.1158/0008-5472.22422980
https://doi.org/10.1158/0008-5472.22422980
Publikováno v:
Cancers, Vol 13, Iss 5678, p 5678 (2021)
Cancers
Cancers
Simple Summary Pediatric high-grade gliomas (pHGGs) are the leading cause of mortality in pediatric neuro-oncology, due in great part to treatment resistance driven by complex DNA repair mechanisms. pHGGs have recently been divided into molecular sub
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
Autor:
Eric Van Dyck, Katrin Neumann, Thibaut Peterlini, Philippe Pasero, Barbara Klink, H. Erasimus, Simone P. Niclou, Lia Pinto, Christel Herold-Mende, Petr V. Nazarov, Diyavarshini Gopaul, Sabrina Fritah, Abhishek Sharma, Marie-Christine Caron, Patrick Calsou, Jean-Yves Masson, Sébastien Britton
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (17), pp.9906-9925. ⟨10.1093/nar/gkab785⟩
Nucleic Acids Research (NAR)
Nucleic Acids Research, Oxford University Press, 2021, 49 (17), pp.9906-9925. ⟨10.1093/nar/gkab785⟩
Nucleic Acids Research (NAR)
Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected seDSB ends is crucial for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a198846723c644dcea0d5d08cbfa5f
https://hal.archives-ouvertes.fr/hal-03371180
https://hal.archives-ouvertes.fr/hal-03371180