Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eric de La Fortelle"'
Autor:
Veronica A. Raker, Johanna M. Avis, Reinhard Lührmann, C. Kambach, Robert I. M. Young, Kiyoshi Nagai, Jade Li, Eric de La Fortelle, S. Walke
Publikováno v:
Cell. 96(3):375-387
The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B′, D1, D2, D3, E, F, and G) in common, which assemble around the Sm site present in four of the major spliceoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3623ae62f2a42c2b23e56a735448544
Publikováno v:
Structure. 6:849-861
Background: The replication origin of the single-stranded (ss)DNA bacteriophage G4 has been proposed to fold into a hairpin loop containing the sequence GCGAAAGC. This sequence comprises a purine-rich motif (GAAA), which also occurs in conserved repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1294c3dbe593c6a6d25433cf6ebc5ed2
https://doi.org/10.1016/s0969-2126(98)00087-2
https://doi.org/10.1016/s0969-2126(98)00087-2
Autor:
John A. Tainer, Eric de La Fortelle, Solange Moréra, Michael A. Gorman, Paul S. Freemont, Clifford D. Mol, Ian D. Hickson, Dominic G. Rothwell
Publikováno v:
The EMBO Journal. 16:6548-6558
The structure of the major human apurinic/ apyrimidinic endonuclease (HAP1) has been solved at 2.2 A resolution. The enzyme consists of two symmetrically related domains of similar topology and has significant structural similarity to both bovine DNa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cf2de2b9800dedede455721f5882b3
https://doi.org/10.1093/emboj/16.21.6548
https://doi.org/10.1093/emboj/16.21.6548
Autor:
Eric de La Fortelle, Jean-Claude Pernollet, Simone Brunie, Jean-Claude Huet, Guillaume Boissy, Gérard Bricogne, Richard A. Kahn
Publikováno v:
Structure. 4:1429-1439
Background: Elicitins form a novel class of plant necrotic proteins which are secreted by Phytophthora and Pythium fungi , parasites of many economically important crops. These proteins induce leaf necrosis in infected plants and elicit an incompatib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aff84487b40fb2d70b247539ce9f694
https://doi.org/10.1016/s0969-2126(96)00150-5
https://doi.org/10.1016/s0969-2126(96)00150-5
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 58:1968-1970
In contrast to academic pursuits of structural genomics, Structural GenomiX (SGX) solves protein structures at high throughput for the main purpose of enhancing drug-discovery projects, either internally or in partnership with pharmaceutical/biotechn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fa10c4cce0db80a975c93b5a148400
https://doi.org/10.1107/s0907444902016852
https://doi.org/10.1107/s0907444902016852
Autor:
George M. Sheldrick, Markus G. Grütter, Eric de La Fortelle, Gérard Bricogne, John P. Priestle, Stefania Di Marco, Peer R. E. Mittl, Isabel Usón
Publikováno v:
Structure (London, England : 1993). 7(1)
Background: Leech-derived inhibitors have a prominent role in the development of new antithrombotic drugs, because some of them are able to block the blood coagulation cascade. Hirustasin, a serine protease inhibitor from the leech Hirudo medicinalis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa62e2f12432923af9cdd74f6dc4b8f3
https://pubmed.ncbi.nlm.nih.gov/10368273
https://pubmed.ncbi.nlm.nih.gov/10368273
Autor:
Eric de La Fortelle, Mark Egerton, Gérard Bricogne, John J. Irwin, Roger Camble, Richard A. Pauptit, Ian W. F. Taylor, Alan Tunnicliffe, Alec D. Tucker, Anil Mistry, Filippo Mancia, Simon A. Weston, Jeremy G. Colls, Gina Rosenbrock
Publikováno v:
Nature structural biology. 5(3)
N-myristoyl transferase (NMT) catalyzes the transfer of the fatty acid myristate from myristoyl-CoA to the N-terminal glycine of substrate proteins, and is found only in eukaryotic cells. The enzyme in this study is the 451 amino acid protein produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2d10fdbe4ec1e27219cc7ffd88fe18
https://pubmed.ncbi.nlm.nih.gov/9501915
https://pubmed.ncbi.nlm.nih.gov/9501915
Autor:
Eric de La Fortelle, John J. Irwin
Publikováno v:
Direct Methods for Solving Macromolecular Structures ISBN: 9789048149940
A graphical user interface1 (GUI) for the crystallographic data processing program SHARP2 has been designed and built from scratch using the hypertext transfer protocol (http). The advantages of this design are as follows. The scripts are easy to wri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3cf08930977c5f24b103d097dc19a5
https://doi.org/10.1007/978-94-015-9093-8_17
https://doi.org/10.1007/978-94-015-9093-8_17
Autor:
Eric de La Fortelle, Gérard Bricogne
Publisher Summary This chapter discusses the maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement (MIR) and multiwavelength anomalous diffraction (MAD). The chapter describes its extension to probability distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50102821b998296ebd52195b5d671d0b
https://doi.org/10.1016/s0076-6879(97)76073-7
https://doi.org/10.1016/s0076-6879(97)76073-7
Autor:
Eric, de La Fortelle, Gérard, Bricogne
Publikováno v:
Methods in enzymology. 276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd80f2dd0193c731c3377cb6b3a853dd
https://pubmed.ncbi.nlm.nih.gov/27799110
https://pubmed.ncbi.nlm.nih.gov/27799110