Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Eric Yvon"'
Autor:
Kajal Chaudhry, Ashley Geiger, Ehsan Dowlati, Haili Lang, Danielle K. Sohai, Eugene I. Hwang, Christopher A. Lazarski, Eric Yvon, Matthias Holdhoff, Richard Jones, Barbara Savoldo, Conrad Russell Y. Cruz, Catherine M. Bollard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 415-430 (2022)
Cord blood (CB)-derived natural killer (NK) cells that are genetically engineered to express a chimeric antigen receptor (CAR) are an attractive off-the-shelf therapy for the treatment of cancer, demonstrating a robust safety profile in vivo. For poo
Externí odkaz:
https://doaj.org/article/2478a16e444f4187b1167f6bf2ee7d0f
Autor:
Bogang Wu, Xiaowen Zhang, Huai-Chin Chiang, Haihui Pan, Bin Yuan, Payal Mitra, Leilei Qi, Hayk Simonyan, Colin N. Young, Eric Yvon, Yanfen Hu, Nu Zhang, Rong Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Negative elongation factor B (NELFB) is one of the four subunits of the NELF complex that controls RNA polymerase II pausing. Here the authors show that, by associating with the key T cell transcription factor TCF1, NELFB is required for eliciting CD
Externí odkaz:
https://doaj.org/article/2778d1c82b674868ad6b34ca40a859a4
Autor:
Scott Raskin, Stacey Van Pelt, Keri Toner, Preethi Bala Balakrishnan, Hema Dave, Catherine M. Bollard, Eric Yvon
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 296-306 (2021)
Summary: The synovial sarcoma X breakpoint 2 (SSX2) belongs to a multigene family of cancer-testis antigens and can be found overexpressed in multiple malignancies. Its restricted expression in immune-privileged normal tissues suggest that SSX2 may b
Externí odkaz:
https://doaj.org/article/1e9a41f1449c4bdfb967452ebe6ee458
Autor:
Nina Shah, Beatriz Martin-Antonio, Hong Yang, Stephanie Ku, Dean A Lee, Laurence J N Cooper, William K Decker, Sufang Li, Simon N Robinson, Takuya Sekine, Simrit Parmar, John Gribben, Michael Wang, Katy Rezvani, Eric Yvon, Amer Najjar, Jared Burks, Indreshpal Kaur, Richard E Champlin, Catherine M Bollard, Elizabeth J Shpall
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76781 (2013)
Natural killer (NK) cells are important mediators of anti-tumor immunity and are active against several hematologic malignancies, including multiple myeloma (MM). Umbilical cord blood (CB) is a promising source of allogeneic NK cells but large scale
Externí odkaz:
https://doaj.org/article/c37a7d4c76584050ad3e3bcf2660a4c7
Autor:
Catherine M. Bollard, Malcolm K. Brenner, Helen E. Heslop, Kathryn Leung, Robert A. Krance, Carlos A. Ramos, George Carrum, Eric Yvon, Barbara Savoldo, Aaron Foster, Sawa Ito, A. John Barrett, Jos Melenhorst, Hao Liu, Meng-Fen Wu, Yasmin Hazrat, Paul Castillo-Caro, Stephanie Ku, Alana A. Kennedy-Nasser
PDF file - 63KB, Supplemental Table 1. Recipients of MRD Grafts who did not receive ULD-IL-2 Supplemental Table 2. Recipients of MUD Grafts who did not receive ULD-IL-2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c072e8a001181ce17dd98a74ce033f1
https://doi.org/10.1158/1078-0432.22455680.v1
https://doi.org/10.1158/1078-0432.22455680.v1
Autor:
Malcolm K. Brenner, Gianpietro Dotti, Andrea Anichini, Aurélie Dutour, Valentina Hoyos, Barbara Savoldo, Michele Del Vecchio, Eric Yvon
Supplementary Data from Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08043336a088bc7732eb7f94b6e9af1d
https://doi.org/10.1158/1078-0432.22440435
https://doi.org/10.1158/1078-0432.22440435
Autor:
Gianpietro Dotti, Soldano Ferrone, Michael Ittmann, Chad J. Creighton, Michele Del Vecchio, Eric Yvon, Ming Zhang, Ignazio Caruana, Valentina Hoyos, Barbara Savoldo, Claudia Geldres
PDF file - 1277K, Immunohistochemistry of normal tissue arrays. Representative immunohistochemistry of normal tissue arrays. Endometrium, lung, skeletal muscle, nerve, skin, and a lung carcinoma are shown. 200X magnification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bd46417d1786b96b267505b999216a
https://doi.org/10.1158/1078-0432.22450254
https://doi.org/10.1158/1078-0432.22450254
Autor:
Gianpietro Dotti, Soldano Ferrone, Michael Ittmann, Chad J. Creighton, Michele Del Vecchio, Eric Yvon, Ming Zhang, Ignazio Caruana, Valentina Hoyos, Barbara Savoldo, Claudia Geldres
PDF file - 94K, Expansion and antitumor activity of T cells expressing a second versus a third generation CAR.CSPG4. Panel A illustrates the expansion of control, CAR.CSPG4 (2nd gen, CD28 costimulation), and CAR.CSPG4 (3rd gen, CD28/4-1BB costimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7b3e0a9103d2f98a16c781d04cf54b
https://doi.org/10.1158/1078-0432.22450245.v1
https://doi.org/10.1158/1078-0432.22450245.v1
Autor:
Catherine M. Bollard, C. Russell Y. Cruz, Rohan Fernandes, Elizabeth Chorvinsky, Eric Yvon, Rachel A. Burga
Purpose:The ability of natural killer (NK) cells to lyse allogeneic targets, without the need for explicit matching or priming, makes them an attractive platform for cell-based immunotherapy. Umbilical cord blood is a practical source for generating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c05a2989d97c5911503b7d2130c991
https://doi.org/10.1158/1078-0432.c.6527523.v1
https://doi.org/10.1158/1078-0432.c.6527523.v1
Autor:
Catherine M. Bollard, Malcolm K. Brenner, Helen E. Heslop, Kathryn Leung, Robert A. Krance, Carlos A. Ramos, George Carrum, Eric Yvon, Barbara Savoldo, Aaron Foster, Sawa Ito, A. John Barrett, Jos Melenhorst, Hao Liu, Meng-Fen Wu, Yasmin Hazrat, Paul Castillo-Caro, Stephanie Ku, Alana A. Kennedy-Nasser
Purpose: GVHD after allogeneic hematopoietic stem cell transplantation (alloSCT) has been associated with low numbers of circulating CD4+CD25+FoxP3+ regulatory T cells (Tregs). Because Tregs express high levels of the interleukin (IL)-2 receptor, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ef41f17b29dc60cb33557b2c04c92b
https://doi.org/10.1158/1078-0432.c.6523082
https://doi.org/10.1158/1078-0432.c.6523082