Zobrazeno 1 - 10
of 438
pro vyhledávání: '"Eric Westhof"'
Autor:
Xiaoling Tong, Min-Jin Han, Kunpeng Lu, Shuaishuai Tai, Shubo Liang, Yucheng Liu, Hai Hu, Jianghong Shen, Anxing Long, Chengyu Zhan, Xin Ding, Shuo Liu, Qiang Gao, Bili Zhang, Linli Zhou, Duan Tan, Yajie Yuan, Nangkuo Guo, Yan-Hong Li, Zhangyan Wu, Lulu Liu, Chunlin Li, Yaru Lu, Tingting Gai, Yahui Zhang, Renkui Yang, Heying Qian, Yanqun Liu, Jiangwen Luo, Lu Zheng, Jinghou Lou, Yunwu Peng, Weidong Zuo, Jiangbo Song, Songzhen He, Songyuan Wu, Yunlong Zou, Lei Zhou, Lan Cheng, Yuxia Tang, Guotao Cheng, Lianwei Yuan, Weiming He, Jiabao Xu, Tao Fu, Yang Xiao, Ting Lei, Anying Xu, Ye Yin, Jian Wang, Antónia Monteiro, Eric Westhof, Cheng Lu, Zhixi Tian, Wen Wang, Zhonghuai Xiang, Fangyin Dai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Tong et al. describe a super pangenome assembled from long-read sequences of 545 wild and domesticated silkworms. Naturally selected (diapause, aposemantic coloration) or artificially selected (silk yield and fineness) sets of genes are delineated.
Externí odkaz:
https://doaj.org/article/f4308507e05b4853986cd98276bfe7e1
Autor:
Carole Trzaska, Séverine Amand, Christine Bailly, Catherine Leroy, Virginie Marchand, Evelyne Duvernois-Berthet, Jean-Michel Saliou, Hana Benhabiles, Elisabeth Werkmeister, Thierry Chassat, Romain Guilbert, David Hannebique, Anthony Mouray, Marie-Christine Copin, Pierre-Arthur Moreau, Eric Adriaenssens, Andreas Kulozik, Eric Westhof, David Tulasne, Yuri Motorin, Sylvie Rebuffat, Fabrice Lejeune
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nonsense mutations can be corrected by several molecules that activate readthrough of premature termination codon. Here, the authors report that 2,6-diaminopurine efficiently corrects UGA nonsense mutations with no significant toxicity.
Externí odkaz:
https://doaj.org/article/970f33637b174d7ca2db00d47c85ff08
Autor:
Alexey Rozov, Iskander Khusainov, Kamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, Marat Yusupov, Eric Westhof, Armin Wagner, Gulnara Yusupova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Metal ions play essential roles in myriads of biological processes, from catalytic co-factors to supporting protein and nucleic acid structures. Here the authors use long-wavelength X-ray diffraction to locate hundreds of potassium ions taking part i
Externí odkaz:
https://doaj.org/article/9be87daf909449729d1006985b3020d8
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
RNA is a unique bio-macromolecule that can both record genetic information and perform biological functions in a variety of molecular processes, including transcription, splicing, translation, and even regulating protein function. RNAs adopt specific
Externí odkaz:
https://doaj.org/article/c41249ab5d0041c09e5571c634bb5fa9
Autor:
Thomas Philipp Hoernes, Klaus Faserl, Michael Andreas Juen, Johannes Kremser, Catherina Gasser, Elisabeth Fuchs, Xinying Shi, Aaron Siewert, Herbert Lindner, Christoph Kreutz, Ronald Micura, Simpson Joseph, Claudia Höbartner, Eric Westhof, Alexander Hüttenhofer, Matthias David Erlacher
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The recognition of the mRNA codon by the tRNA anticodon is crucial for protein synthesis. Here the authors introduce non-standard nucleotides in bacterial and eukaryotic mRNA to reveal the minimal hydrogen bond requirement of codon-anticodon interact
Externí odkaz:
https://doaj.org/article/ffffbc1b3a5340bdb59935247e94c0d4
Autor:
Alexey Rozov, Natalia Demeshkina, Iskander Khusainov, Eric Westhof, Marat Yusupov, Gulnara Yusupova
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The anticodon loops of almost all tRNAs contain modifications known to be important for their function. Here the authors use crystallography to provide new mechanistic insights into how the modification at the wobble position of the E. coli tRNALysUU
Externí odkaz:
https://doaj.org/article/79069a8223ce49d8a433c23959c69e98
Autor:
Zhichao Miao, Eric Westhof
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004639 (2015)
Computational prediction of nucleic acid binding sites in proteins are necessary to disentangle functional mechanisms in most biological processes and to explore the binding mechanisms. Several strategies have been proposed, but the state-of-the-art
Externí odkaz:
https://doaj.org/article/1f8a4fb4d5424c20bbdc6de2abf7d503
Publikováno v:
RNA. 29:551-556
Analysis of the profile of the tRNA modifications in severalArchaeaallowed us to observe a novel modified uridine in the V-loop of several tRNAs from two species:Pyrococcus furiosusandSulfolobus acidocaldarius. Recently, Ohira and colleagues characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac5ff46dc2e8b82e4a58ec5ba8ba35e
https://doi.org/10.1261/rna.079546.122
https://doi.org/10.1261/rna.079546.122
Autor:
Rhiju Das, Rachael C. Kretsch, Adam Simpkin, Thomas Mulvaney, Phillip Pham, Ramya Rangan, Fan Bu, Ronan Keegan, Maya Topf, Daniel Rigden, Zhichao Miao, Eric Westhof
The prediction of RNA three-dimensional structures remains an unsolved problem. Here, we report double-blind assessments of RNA structure predictions in CASP15, the first CASP exercise in which RNA modeling was assessed. Forty two predictor groups su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::691d02f5a5b89eb7036874bcc40f20b8
https://doi.org/10.1101/2023.04.25.538330
https://doi.org/10.1101/2023.04.25.538330
Publikováno v:
RNA. 28:729-741
The 5′UTR part of coronavirus genomes plays key roles in the viral replication cycle and translation of viral mRNAs. The first 75–80 nt, also called the leader sequence, are identical for genomic mRNA and subgenomic mRNAs. Recently, it was shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b12462ac7674bf7243db8a5f0220e5
https://doi.org/10.1261/rna.078972.121
https://doi.org/10.1261/rna.078972.121