Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Eric W Jones"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In exponential population growth, variability in the timing of individual division events and environmental factors (including stochastic inoculation) compound to produce variable growth trajectories. In several stochastic models of exponent
Externí odkaz:
https://doaj.org/article/6196a61ca36948efa46b4e49eca8a25d
Autor:
Ren Dodge, Eric W. Jones, Haolong Zhu, Benjamin Obadia, Daniel J. Martinez, Chenhui Wang, Andrés Aranda-Díaz, Kevin Aumiller, Zhexian Liu, Marco Voltolini, Eoin L. Brodie, Kerwyn Casey Huang, Jean M. Carlson, David A. Sivak, Allan C. Spradling, William B. Ludington
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Animal gut microbiomes are fairly stable over time despite large daily fluctuations in diet and introductions of environmental bacteria. Here the authors report that fruit flies maintain the stability of their microbiome in part through a physical ni
Externí odkaz:
https://doaj.org/article/eb76463966cf4a3ab94fc6c10309366d
Autor:
Eric W Jones, Jean M Carlson
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1006001 (2018)
In this paper we study antibiotic-induced C. difficile infection (CDI), caused by the toxin-producing C. difficile (CD), and implement clinically-inspired simulated treatments in a computational framework that synthesizes a generalized Lotka-Volterra
Externí odkaz:
https://doaj.org/article/8c198caddf3b4fef95402096856cc5ca
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 7
Observational studies reveal substantial variability in microbiome composition across individuals. Targeted studies in gnotobiotic animals underscore this variability by showing that some bacterial strains colonize deterministically, while others col
Autor:
Benjamin Obadia, Liu Z, Jean M. Carlson, Voltolini M, Martinez Dj, David A. Sivak, Ren Dodge, Eric W. Jones, Allan C. Spradling, Kerwyn Casey Huang, Heng Zhu, Eoin L. Brodie, William B. Ludington, Andrés Aranda-Díaz, Aumiller K, Chen Wang
The intestines of animals are typically colonized by a complex, relatively stable microbiota that influences health and fitness, but the underlying mechanisms of colonization remain poorly understood. As a typical animal, the fruit fly, Drosophila me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714af48edf9400a4ed38f095e23e799f
https://doi.org/10.1101/2021.09.30.462663
https://doi.org/10.1101/2021.09.30.462663
Observational studies reveal substantial variability in microbiome composition across individuals. While some of this variability can be explained by external factors like environmental, dietary, and genetic differences between individuals, in this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f921034fa0fe36093ac0c6cf2ba9fad
https://doi.org/10.1101/2021.08.29.458111
https://doi.org/10.1101/2021.08.29.458111
Control of ecological outcomes through deliberate parameter changes in a model of the gut microbiome
Publikováno v:
Physical Review E. 101
The generalized Lotka-Volterra (gLV) equations are a mathematical proxy for ecological dynamics. We focus on a gLV model of the gut microbiome, in which the evolution of the gut microbial state is determined in part by pairwise inter-species interact
Publikováno v:
Journal of Theoretical Biology
Highlights • Innate-adaptive immune collaboration deteriorates with age, resulting in fragility. • Imbalance of the adaptive repertoire triggers chronic inflammation in the elderly. • Variability in the onset of fragility arises from individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860853169f0d430d3f68393e80c6e728
Autor:
Eric W. Jones, Jean M. Carlson
Publikováno v:
Physical Review E. 99
The generalized Lotka-Volterra (gLV) equations, a classic model from theoretical ecology, describe the population dynamics of a set of interacting species. As the number of species in these systems grow in number, their dynamics become increasingly c
Autor:
Nikolaos Korasidis, Lisa Lamberti, William B. Ludington, Eric W. Jones, Alison L. Gould, Niko Beerenwinkel, Vivian Zhang, Alex Gavryushkin, Jean M. Carlson, Benjamin Obadia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 115 (51)
Proceedings of the National Academy of Sciences of the United States of America, 115 (51)
Gut bacteria can affect key aspects of host fitness, such as development, fecundity, and lifespan, while the host, in turn, shapes the gut microbiome. However, it is unclear to what extent individual species versus community interactions within the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6d533a2d74b20357aaa1aa5c646bb8