Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eric W Jeffery"'
Autor:
Justin C Fay, Ping Liu, Giang T Ong, Maitreya J Dunham, Gareth A Cromie, Eric W Jeffery, Catherine L Ludlow, Aimée M Dudley
Publikováno v:
PLoS Biology, Vol 17, Iss 3, p e3000147 (2019)
Strains of Saccharomyces cerevisiae used to make beer, bread, and wine are genetically and phenotypically distinct from wild populations associated with trees. The origins of these domesticated populations are not always clear; human-associated migra
Externí odkaz:
https://doaj.org/article/b6c4bad4d618493585da401d4f802499
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 233-246 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Aneuploidy, a state in which the chromosome number deviates from a multiple of the haploid count, significantly impacts human health. The phenotypic consequences of aneuploidy are believed to arise from gene expression changes associated with the alt
Autor:
Maitreya J. Dunham, Gareth A. Cromie, Ping Liu, Catherine L. Ludlow, Giang T. Ong, Eric W. Jeffery, Aimée M. Dudley, Justin C. Fay
Publikováno v:
PLoS Biology
PLoS Biology, Vol 17, Iss 3, p e3000147 (2019)
PLoS Biology, Vol 17, Iss 3, p e3000147 (2019)
Strains of Saccharomyces cerevisiae used to make beer, bread, and wine are genetically and phenotypically distinct from wild populations associated with trees. The origins of these domesticated populations are not always clear; human-associated migra
Autor:
Waracharee Srifa, Anja Forche, Norma V. Solis, Eric W. Jeffery, Darren Abbey, Scott G. Filler, Gareth A. Cromie, Tippapha Pisithkul, Aleeza C. Gerstein, Judith Berman, Aimée M. Dudley
Publikováno v:
Genetics, vol 209, iss 3
In vitro studies suggest that stress may generate random standing variation and that different cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been tested with pathogenic fungi growing within their host niche in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e055d71edf80222fbc7fd5840b8047e8
https://escholarship.org/uc/item/7r01d4gs
https://escholarship.org/uc/item/7r01d4gs
Autor:
Anja Forche, Waracharee Srifa, Scott G. Filler, Aleeza C. Gerstein, Aimée M. Dudley, Gareth A. Cromie, Norma V. Solis, Eric W. Jeffery, Judith Berman, Tippapha Pisithkul
In vitro studies suggest that stress may generate random standing variation, and that different cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been tested with pathogenic fungi growing within their host niche i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcc0305c21cf8c0dfb5782793b2935d
Autor:
Aimée M. Dudley, Catherine L. Ludlow, Amy Sirr, Teresa L Gilbert, Gareth A. Cromie, Adrian C. Scott, Eric W. Jeffery
Publikováno v:
Genetics
Clinically relevant features of monogenic diseases, including severity of symptoms and age of onset, can vary widely in response to environmental differences as well as to the presence of genetic modifiers affecting the trait’s penetrance and expre
Autor:
Zhihao Tan, Aimée M. Dudley, Michelle Hays, Vida Ahyong, Amy Sirr, Alexander Skupin, Eric W. Jeffery, Adrian C. Scott, Gareth A. Cromie
Publikováno v:
Proceedings of the National Academy of Sciences. 110:12367-12372
Although microorganisms are traditionally used to investigate unicellular processes, the yeast Saccharomyces cerevisiae has the ability to form colonies with highly complex, multicellular structures. Colonies with the “fluffy” morphology have pro
Autor:
Gareth A. Cromie, Aimée M. Dudley, Amy Sirr, Eric W. Jeffery, Adrian C. Scott, Michelle Hays, Patrick May, Teresa L. Gilbert, Catherine L. Ludlow, Jake Lin
Publikováno v:
Nature methods
Tetrad analysis has been a gold standard genetic technique for several decades. Unfortunately, the manual nature of the process has relegated its application to small-scale studies and limited its integration with rapidly evolving DNA sequencing tech
Autor:
Michelle Hays, Amy Sirr, Gareth A. Cromie, Justin C. Fay, Cecilia Garmendia-Torres, Catherine L. Ludlow, Eric W. Jeffery, Aimée M. Dudley, Colburn Field
Publikováno v:
Current biology : CB. 26(7)
Modern transportation networks have facilitated the migration and mingling of previously isolated populations of plants, animals, and insects. Human activities can also influence the global distribution of microorganisms. The best-understood example
Autor:
Richard J. Ulevitch, Michael J. Lacy, Jean da Silva Correia, Jory R. Baldridge, Eric W. Jeffery, Peter Probst, Cluff Christopher W, Axel G. Stöver, Johnson David A, Mark Elliott, Robert M. Hershberg, David H. Persing, Jay T. Evans
Publikováno v:
Journal of Biological Chemistry. 279:4440-4449
Important questions remain regarding the impact of variations in the structure of the lipid A portion of lipopolysaccharide on activation of cells via the Toll-like receptor 4 complex. We have studied a series of synthetic lipid A mimetic compounds k