Výsledky vyhledávání - "Eric Torstenson"

Akademický článek

Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space

Autor: Michael C. Schatz, Anthony A. Philippakis, Enis Afgan, Eric Banks, Vincent J. Carey, Robert J. Carroll, Alessandro Culotti, Kyle Ellrott, Jeremy Goecks, Robert L. Grossman, Ira M. Hall, Kasper D. Hansen, Jonathan Lawson, Jeffrey T. Leek, Anne O’Donnell Luria, Stephen Mosher, Martin Morgan, Anton Nekrutenko, Brian D. O’Connor, Kevin Osborn, Benedict Paten, Candace Patterson, Frederick J. Tan, Casey Overby Taylor, Jennifer Vessio, Levi Waldron, Ting Wang, Kristin Wuichet, Alexander Baumann, Andrew Rula, Anton Kovalsy, Clare Bernard, Derek Caetano-Anollés, Geraldine A. Van der Auwera, Justin Canas, Kaan Yuksel, Kate Herman, M. Morgan Taylor, Marianie Simeon, Michael Baumann, Qi Wang, Robert Title, Ruchi Munshi, Sushma Chaluvadi, Valerie Reeves, William Disman, Salin Thomas, Allie Hajian, Elizabeth Kiernan, Namrata Gupta, Trish Vosburg, Ludwig Geistlinger, Marcel Ramos, Sehyun Oh, Dave Rogers, Frances McDade, Mim Hastie, Nitesh Turaga, Alexander Ostrovsky, Alexandru Mahmoud, Dannon Baker, Dave Clements, Katherine E.L. Cox, Keith Suderman, Nataliya Kucher, Sergey Golitsynskiy, Samantha Zarate, Sarah J. Wheelan, Kai Kammers, Ana Stevens, Carolyn Hutter, Christopher Wellington, Elena M. Ghanaim, Ken L. Wiley, Jr., Shurjo K. Sen, Valentina Di Francesco, Deni s Yuen, Brian Walsh, Luke Sargent, Vahid Jalili, John Chilton, Lori Shepherd, B.J. Stubbs, Ash O’Farrell, Benton A. Vizzier, Jr., Charles Overbeck, Charles Reid, David Charles Steinberg, Elizabeth A. Sheets, Julian Lucas, Lon Blauvelt, Louise Cabansay, Noah Warren, Brian Hannafious, Tim Harris, Radhika Reddy, Eric Torstenson, M. Katie Banasiewicz, Haley J. Abel, Jason Walker

Publikováno v: Cell Genomics, Vol 2, Iss 1, Pp 100085- (2022)

Summary: The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL; https://anvilproject.org) was developed to address a widespread community need for a unified computing environment for genomics data storage, managemen

Externí odkaz: https://doaj.org/article/95ac1623e901491c821d128f529da364

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Periconceptional folic acid supplementation and child asthma: a

Autor: Margaret A, Adgent, Shanda, Vereen, Alexis, McCullough, Sarah H, Jones, Eric, Torstenson, Digna R, Velez Edwards, Katherine E, Hartmann, Kecia N, Carroll

Publikováno v: The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25)

High maternal folic acid exposure has been studied as a risk factor for child asthma with inconclusive results. Folic acid supplementation that begins before pregnancy may propagate high exposures during pregnancy, particularly in regions with fortif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9a5a2a229867f203fc39e12c72c8e91
https://pubmed.ncbi.nlm.nih.gov/36117404

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African ancestry genome-wide association study of blood pressure and hypertension identifies 25 novel loci through predicted gene expression

African Americans (AAs) experience a high burden of hypertension but have been underrepresented in genetic studies of blood pressure. We performed common and rare variant genome-wide association studies (GWAS) of systolic (SBP) and diastolic (DBP) bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7692bcd1faf47e7e5eb568f2f97fc130
https://doi.org/10.21203/rs.3.rs-1392991/v1

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Akademický článek

Recurrent tissue-specific mtDNA mutations are common in humans.

Autor: David C Samuels, Chun Li, Bingshan Li, Zhuo Song, Eric Torstenson, Hayley Boyd Clay, Antonis Rokas, Tricia A Thornton-Wells, Jason H Moore, Tia M Hughes, Robert D Hoffman, Jonathan L Haines, Deborah G Murdock, Douglas P Mortlock, Scott M Williams

Publikováno v: PLoS Genetics, Vol 9, Iss 11, p e1003929 (2013)

Mitochondrial DNA (mtDNA) variation can affect phenotypic variation; therefore, knowing its distribution within and among individuals is of importance to understanding many human diseases. Intra-individual mtDNA variation (heteroplasmy) has been gene

Externí odkaz: https://doaj.org/article/e558b901385c4b18869fa94979a453a1

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Akademický článek

Evaluating power and type 1 error in large pedigree analyses of binary traits.

Autor: Anna C Cummings, Eric Torstenson, Mary F Davis, Laura N D'Aoust, William K Scott, Margaret A Pericak-Vance, William S Bush, Jonathan L Haines

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e62615 (2013)

Studying population isolates with large, complex pedigrees has many advantages for discovering genetic susceptibility loci; however, statistical analyses can be computationally challenging. Allelic association tests need to be corrected for relatedne

Externí odkaz: https://doaj.org/article/b37d728679c24e7fb47d0ebf97c34124

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Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

Autor: William S, Bush, Jonathan, Boston, Sarah A, Pendergrass, Logan, Dumitrescu, Robert, Goodloe, Kristin, Brown-Gentry, Sarah, Wilson, Bob, McClellan, Eric, Torstenson, Melissa A, Basford, Kylee L, Spencer, Marylyn D, Ritchie, Dana C, Crawford

Publikováno v: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.

Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples linked to clinical outcomes and quantitative tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90fbaa97671d23a8281cd5bdd4e295ee
https://pubmed.ncbi.nlm.nih.gov/23424142

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P1‐268: Discovery and Replication of Gene‐Gene Interactions in Multiple Independent Datasets from the Alzheimer Disease Genetics Consortium

Autor: Tricia Thornton‐Wells, Eric Torstenson, Scott Dudek, Marylyn Ritchie, Eden Martin, Margaret Pericak‐Vance, Jonathan Haines, null The Alzheimer's Disease Genetics Consortium

Publikováno v: Alzheimer's & Dementia. 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae5d0c61f2c9521208e4584bbdb2722c
https://doi.org/10.1016/j.jalz.2011.05.548

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Finding unique filter sets in PLATO: a precursor to efficient interaction analysis in GWAS data

Autor: Benjamin J, Grady, Eric, Torstenson, Scott M, Dudek, Justin, Giles, David, Sexton, Marylyn D, Ritchie

Publikováno v: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.

The methods to detect gene-gene interactions between variants in genome-wide association study (GWAS) datasets have not been well developed thus far. PLATO, the Platform for the Analysis, Translation and Organization of large-scale data, is a filter-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba87558b839b20b69247a84b5a37e320
https://pubmed.ncbi.nlm.nih.gov/19908384

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