Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eric T. Pleim"'
Facilitation of Sexual Receptivity by Ventromedial Hypothalamic Implants of the Antiprogestin RU 486
Publikováno v:
Hormones and Behavior. 27:488-498
RU 486 is known primarily as an antagonist to progestins and glucocorticoids. However, RU 486 has also been shown to have agonistic progestational properties in biochemical and behavioral studies. In the current study, RU 486 was implanted directly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d58ba963dd03013930f4f2070c0d3b
https://doi.org/10.1006/hbeh.1993.1035
https://doi.org/10.1006/hbeh.1993.1035
Publikováno v:
Hormones and Behavior. 24:301-310
The progestin receptor antagonist RU 38486 (henceforth referred to as RU 486) was tested for facilitative effects on female receptive behavior in ovariectomized Long-Evans rats primed with 2 micrograms estradiol benzoate (EB). RU 486 (0, 0.5, 1.6, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eed053df37ff9624ec163ea24fd19a5
https://doi.org/10.1016/0018-506x(90)90011-l
https://doi.org/10.1016/0018-506x(90)90011-l
Publikováno v:
Brain Research. 524:160-163
Extracellular dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) in the nucleus accumbens (N. Acc.) were measured by in vivo microdialysis during male sexual activity. DA and DOPAC were significantly increased during copulation, but not during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1cac4dca51c5b4e95827c739acca51
https://doi.org/10.1016/0006-8993(90)90507-8
https://doi.org/10.1016/0006-8993(90)90507-8
Publikováno v:
Pharmacology, biochemistry, and behavior. 41(1)
RU 38486 (RU 486, mifepristone) is a potent progesterone receptor antagonist that has been used in humans in the pharmacologic induction of abortion. The effects of exposure to RU 486 during the neonatal period of the rat has not been previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5d72ccfe3695041dbc6d95fcf9a933
https://pubmed.ncbi.nlm.nih.gov/1539081
https://pubmed.ncbi.nlm.nih.gov/1539081
Publikováno v:
Hormones and behavior. 25(1)
Progesterone (P) facilitation of sexual receptivity in rodents has been achieved by intracranial administration to the ventral hypothalamus; the preoptic area; and midbrain areas such as central gray, mesencephalic reticular formation, and ventral te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58867a8f7e6bc2a7841cf2d0009e4d14
https://pubmed.ncbi.nlm.nih.gov/2045089
https://pubmed.ncbi.nlm.nih.gov/2045089
Publikováno v:
Hormones and behavior. 24(2)
Intracranial implantation experiments have shown that the ventromedial hypothalamus (VMH) is the most sensitive site for the facilitation of female sexual behavior by progesterone in estrogen-primed rats. However, similar implantation techniques have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63fd244d5bfe700182c503be8b02c08
https://pubmed.ncbi.nlm.nih.gov/2365298
https://pubmed.ncbi.nlm.nih.gov/2365298
Autor:
Joseph F. DeBold, Eric T. Pleim
Publikováno v:
Physiology & Behavior. 32:743-747
In a series of experiments, we studied the biphasic actions of 4 progestins on sexual receptivity in female hamsters. Based on previous reports, we selected doses of progesterone (P), desoxycorticosterone acetate (DOCA), 5-alpha-dihydroprogesterone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82565601924fcd0621d4352abff7ea3b
https://doi.org/10.1016/0031-9384(84)90188-4
https://doi.org/10.1016/0031-9384(84)90188-4
Publikováno v:
Endocrinology. 124:1807-1812
The ventromedial nucleus of the hypothalamus (VMN) is thought to constitute an essential neural substrate for hormonal induction of female sexual behavior. In previous work, implants of dilute (0.4%) estradiol (E2) have been found to prime progestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7520453b84dda5dd8f241ea06b8714
https://doi.org/10.1210/endo-124-4-1807
https://doi.org/10.1210/endo-124-4-1807
Autor:
Joseph F. DeBold, Eric T. Pleim
Publikováno v:
Brain research bulletin. 21(4)
The ventromedial nucleus of the hypothalamus (VMH) has been implicated in the mediation of the hormonal control of female rodent sexual behavior. However, in hamsters, progesterone (P) has been found to have effects on sexual receptivity in other die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1379fa6546d3484741101f957dfd4416
https://pubmed.ncbi.nlm.nih.gov/3208146
https://pubmed.ncbi.nlm.nih.gov/3208146
Autor:
Eric T. Pleim, Ronald J. Barfield
Publikováno v:
Hormones and behavior. 22(2)
The CNS sites of action for progesterone facilitation of female sexual behavior are disputed. Among the areas most often cited are the ventromedial hypothalamus and the ventral midbrain. There is also a controversy about whether estradiol may substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abea5b9769fc7404a033d2eb6088e74a
https://pubmed.ncbi.nlm.nih.gov/3397048
https://pubmed.ncbi.nlm.nih.gov/3397048