Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eric Solis"'
Autor:
Eric Solis, Allegra Terhorst, Acer E Xu, Christopher M. Brennan, Andrew J Kane, Angelika Amon, Vladimir Denic
Publikováno v:
Molecular Biology of the Cell
Aneuploid yeast cells are in a chronic state of proteotoxicity, yet do not constitutively induce the cytosolic unfolded protein response, or heat shock response (HSR) by heat shock factor 1 (Hsf1). Here, we demonstrate that an active environmental st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c75fc5fdfc6c70b14e04e2741d27014
https://pubmed.ncbi.nlm.nih.gov/34191542
https://pubmed.ncbi.nlm.nih.gov/34191542
Autor:
Eric Solis, Dexter X. Jin, Jai P. Pandey, Vladimir Denic, Xu Zheng, Piyush Gupta, David Pincus, Edoardo M. Airoldi
Publikováno v:
PMC
Despite its eponymous association with the heat shock response, yeast heat shock factor 1 (Hsf1) is essential even at low temperatures. Here we show that engineered nuclear export of Hsf1 results in cytotoxicity associated with massive protein aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464d2e2353416b04e8221908b1367ed5
https://doi.org/10.1016/j.molcel.2016.05.014
https://doi.org/10.1016/j.molcel.2016.05.014
Autor:
Heather Sadlish, Matthew C. Lucas, Vikram Khurana, Kenneth J. Rhodes, Waseem K. Raja, Yiqun Chen, Rebecca Aron, Daniel F. Tardiff, Radha Subramaniam, Bertrand Le Bourdonnec, Eric Solis, Dimple B. Doshi, Jeff S. Piotrowski, Benjamin Vincent, Chee Yeun Chung, Michelle Pires, Helene Bacherman, Robert H. Scannevin
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2742-2754.e31 (2018)
Summary: The lack of disease-modifying treatments for neurodegenerative disease stems in part from our rudimentary understanding of disease mechanisms and the paucity of targets for therapeutic intervention. Here we used an integrated discovery parad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a75f18a06a8862347b829814d3bbc2
https://doi.org/10.1016/j.celrep.2018.11.028
https://doi.org/10.1016/j.celrep.2018.11.028