Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eric Samarut"'
Autor:
Jen-Jie Lee, Tong Wang, Kali Wiggins, Po Nien Lu, Christina Underwood, Katarzyna Ochenkowska, Eric Samarut, Laura M. Pollard, Heather Flanagan-Steet, Richard Steet
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109293- (2024)
Summary: The classic view of the lysosome as a static recycling center has been replaced with one of a dynamic and mobile hub of metabolic regulation. This revised view raises new questions about how dysfunction of this organelle causes pathology in
Externí odkaz:
https://doaj.org/article/9d229b2a21904723996c072b771dd568
Autor:
Dorota Nieoczym, Marta Marszalek-Grabska, Radoslaw Szalak, Uday Kundap, Agnieszka A. Kaczor, Tomasz M. Wrobel, Nataliia Kosheva, Malgorzata Komar, Michal Abram, Camila V. Esguerra, Eric Samarut, Mateusz Pieróg, Marcin Jakubiec, Krzysztof Kaminski, Wirginia Kukula-Koch, Kinga Gawel
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116234- (2024)
Previously, we demonstrated that palmatine (PALM) – an isoquinoline alkaloid from Berberis sibrica radix, exerted antiseizure activity in the pentylenetetrazole (PTZ)-induced seizure assay in larval zebrafish. The aim of the present study was to mo
Externí odkaz:
https://doaj.org/article/78be2bd0abc84046aa1af304dd7186db
Autor:
Eric Samarut, Domitille Chalopin, Raphaëlle Riché, Marc Allard, Meijiang Liao, Pierre Drapeau
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216159 (2019)
Glycine receptors (GlyRs) are ligand-gated chloride channels mediating inhibitory neurotransmission in the brain stem and spinal cord. They function as pentamers composed of alpha and beta subunits for which 5 genes have been identified in human (GLR
Externí odkaz:
https://doaj.org/article/be41e4118bb241c0b194043186ed7fa0
Autor:
Scott C. Baraban, Eric Samarut, Mark P. Richardson, Richard E. Rosch, Dominic R. W. Burrows, Martin P. Meyer, J. Liu
Publikováno v:
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Our understanding of the genetic aetiology of paediatric epilepsies has grown substantially over the last decade. However, in order to translate improved diagnostics to personalised treatments, there is an urgent need to link molecular pathophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76be105e65766f899949cba12f40fc43
https://doi.org/10.1016/j.ejpn.2020.01.006
https://doi.org/10.1016/j.ejpn.2020.01.006
Autor:
Eric Samarut, Mohd Farooq Shaikh, Faridah Abas, Siti Munirah Mohd Faudzi, Uday P. Kundap, Brandon Kar Meng Choo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss, Pp 112035-(2021)
Seizures are the outward manifestation of abnormally excessive or synchronous brain activity. While seizures can be somewhat symptomatically managed with anti-epileptic drugs (AEDs), many patients are still refractory to the currently available AEDs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093620c855b7d891f189bf1525ce1d02
https://pubmed.ncbi.nlm.nih.gov/34411917
https://pubmed.ncbi.nlm.nih.gov/34411917
Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression
Autor:
Shunmoogum A. Patten, Eric Samarut, Tatiana Cardinal, Betelhem Kassa, Nicolas Pilon, Priyanka Jamadagni, J. Alex Parker, Kathrin Schmeisser, Maximilian Breuer
Publikováno v:
EMBO Reports
Mutations in the chromatin remodeller‐coding gene CHD7 cause CHARGE syndrome (CS). CS features include moderate to severe neurological and behavioural problems, clinically characterized by intellectual disability, attention‐deficit/hyperactivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d004c5a3313a0a8ba461695a60227e31
http://europepmc.org/articles/PMC8183419
http://europepmc.org/articles/PMC8183419
Autor:
Nathalie Lepage, Izabella A. Pena, Eric Samarut, Kit-Yi Leung, Pierre Drapeau, Kyriakie Sarafoglou, Nicolas D.E. Greene, Raphaëlle Riché, Meijiang Liao, Lisa A. Schimmenti
Publikováno v:
JCI Insight. 3
Glycine encephalopathy (GE), or nonketotic hyperglycinemia (NKH), is a rare recessive genetic disease caused by defective glycine cleavage and characterized by increased accumulation of glycine in all tissues. Here, based on new case reports of GLDC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39ea84cfc4cffa67985ccbaf6b722dc
https://doi.org/10.1172/jci.insight.124642
https://doi.org/10.1172/jci.insight.124642
Autor:
Eric Samarut, Patrick Cossette, Liselotte Dufour, Marc Allard, Nadia Soussi-Yanicostas, Solène Renault, Rahma Hassan-Abdi, Pierre Drapeau, Amrutha Swaminathan, Meijiang Liao, Raphaëlle Riché
Publikováno v:
Epilepsia
Epilepsia, Wiley, 2018, 59 (11), pp.2061-2074. ⟨10.1111/epi.14576⟩
Epilepsia, Wiley, 2018, 59 (11), pp.2061-2074. ⟨10.1111/epi.14576⟩
International audience; Objective: In humans, mutations of the γ-aminobutyric acid receptor subunit 1 (GABRA1) cause either mild or severe generalized epilepsy. Although these epilepsy causing mutations have been shown to disrupt the receptor activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8522e01c9dd97d255bad4168a716f30
https://hal.archives-ouvertes.fr/hal-02357189/file/Samarut_et_al-2018-Epilepsia.pdf
https://hal.archives-ouvertes.fr/hal-02357189/file/Samarut_et_al-2018-Epilepsia.pdf
Publikováno v:
Innovation at the NHP/Food Interface.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0d6ac14e761a7a0b72b7a8ae82c9fb
https://doi.org/10.1055/s-0038-1644918
https://doi.org/10.1055/s-0038-1644918
Publikováno v:
Zebrafish, 15, 79-83
Zebrafish, 15, 1, pp. 79-83
Zebrafish, 15, 1, pp. 79-83
Item does not contain fulltext 01 februari 2018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953b1356c868876b478794122ec3f2ec
https://doi.org/10.1089/zeb.2017.1518
https://doi.org/10.1089/zeb.2017.1518