Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Eric S. Simon"'
Autor:
Elke Lipka, Aaron M. Chadderdon, Cheryl C. Harteg, Matthew K. Doherty, Eric S. Simon, John M. Domagala, Dawn M. Reyna, Kim M. Hutchings, Xinmin Gan, Andrew D. White, Caroll B. Hartline, Emma A. Harden, Kathy A. Keith, Mark N. Prichard, Scott H. James, Rhonda D. Cardin, David I. Bernstein, Jacqueline F. Spencer, Ann E. Tollefson, William S. M. Wold, Karoly Toth
Publikováno v:
Molecular pharmaceutics. 20(1)
DNA viruses are responsible for many diseases in humans. Current treatments are often limited by toxicity, as in the case of cidofovir (CDV, Vistide), a compound used against cytomegalovirus (CMV) and adenovirus (AdV) infections. CDV is a polar molec
Autor:
Phil Andrews, Eric S. Simon
Publikováno v:
Analytical biochemistry. 581
A previous approach was established that allowed direct identification of pyridoxal-5ˊ-phosphate (PLP) bonding sites in proteins using mass spectrometry after tryptic proteolysis. The approach required peptide mass fingerprinting owing to suppressed
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:1619-1630
RATIONALE In protein studies that employ tandem mass spectrometry the manipulation of protonated peptide fragmentation through exclusive dissociation pathways may be preferred in some applications over the comprehensive amide backbone fragmentation t
Publikováno v:
Rapid Communications in Mass Spectrometry. 26:631-638
Motivated by the need for chemical strategies designed to tune peptide fragmentation to selective cleavage reactions, benzyl ring substituent influence on the relative formation of carbocation elimination (CCE) products from peptides with benzylamine
Publikováno v:
Journal of Biological Chemistry. 285:7197-7207
During mitosis, the stacked structure of the Golgi undergoes a continuous fragmentation process. The generated mitotic fragments are evenly distributed into the daughter cells and reassembled into new Golgi stacks. This disassembly and reassembly pro
Autor:
John Allison, Eric S. Simon
Publikováno v:
Rapid Communications in Mass Spectrometry. 23:3401-3408
Peptides modified by pyridoxal-5'-phosphate (PLP), linked to a lysine residue via reductive amination, exhibit distinct spectral characteristics in the collision-induced dissociation (CID) tandem mass (MS/MS) spectra that are described here. The MS/M
Publikováno v:
Molecular microbiology, vol 69, iss 3
Molecular Microbiology
Molecular Microbiology
Myxococcus xanthus is a gliding bacterium with a complex life cycle that includes swarming, predation and fruiting body formation. Directed movements in M. xanthus are regulated by the Frz chemosensory system, which controls cell reversals. The Frz p
Publikováno v:
Analytical Biochemistry. 377:234-242
Improvements to phosphopeptide enrichment protocols employing titanium dioxide (TiO2) are described and applied to identification of phosphorylation sites on recombinant human cyclin-dependent kinase 2 (CDK2). Titanium dioxide binds phosphopeptides u
Autor:
Sarah L. Tomanicek-Volk, Eric S. Simon, Mary C. Hurley, John A. Williams, Philip C. Andrews, Angela K. Walker, Stephen A. Ernst, John R. Strahler, Xuequn Chen, Bradley Nelson
Publikováno v:
Molecular & Cellular Proteomics. 5:306-312
The zymogen granule (ZG) is the specialized organelle in pancreatic acinar cells for digestive enzyme storage and regulated secretion and has been a model for studying secretory granule functions. In an initial effort to comprehensively understand th
Autor:
Stefan Mellema, Michael G. Kocsis, David Rhodes, Mitchell C. Tarczynski, Kazuki Saito, Philippe Ranocha, Eric S. Simon, Conrad Wagner, Changjiang Li, Andrew D. Hanson, Motoko Awazuhara, Robert B. Meeley, Douglas A. Gage, Gregory J. Peel
Publikováno v:
Plant Physiology. 131:1808-1815
Methionine (Met) S-methyltransferase (MMT) catalyzes the synthesis of S-methyl-Met (SMM) from Met andS-adenosyl-Met (Ado-Met). SMM can be reconverted to Met by donating a methyl group to homocysteine (homo-Cys), and concurrent operation of this react