Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Eric S. Pringle"'
Autor:
Eric S Pringle, Brett A Duguay, Maxwell P Bui-Marinos, Rory P Mulloy, Shelby L Landreth, Krishna Swaroop Desireddy, Stacia M Dolliver, Shan Ying, Taylor Caddell, Trinity H Tooley, Patrick D Slaine, Stephen L Bearne, Darryl Falzarano, Jennifer A Corcoran, Denys A Khaperskyy, Craig McCormick
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010832 (2022)
There is an outstanding need for broadly acting antiviral drugs to combat emerging viral diseases. Here, we report that thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2. 6-Thioguanine (6-TG) disrupted early stages
Externí odkaz:
https://doaj.org/article/e4051cc5cb3d4a36881ae54bc20ae244
Autor:
Brett A. Duguay, Adrian Herod, Eric S. Pringle, Susan M. A. Monro, Marc Hetu, Colin G. Cameron, Sherri A. McFarland, Craig McCormick
Publikováno v:
Viruses, Vol 14, Iss 1, p 110 (2022)
Photodynamic inactivation (PDI) employs a photosensitizer, light, and oxygen to create a local burst of reactive oxygen species (ROS) that can inactivate microorganisms. The botanical extract PhytoQuinTM is a powerful photosensitizer with antimicrobi
Externí odkaz:
https://doaj.org/article/6a7e79cfefcb4b6681100f6fd0819f71
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008185 (2019)
Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins.
Externí odkaz:
https://doaj.org/article/289ed4d5143b48a5a480f81574fb7115
Autor:
Eric S. Pringle, Craig McCormick
Publikováno v:
Proceedings, Vol 50, Iss 1, p 119 (2020)
Herpesvirus genomes are decoded by host RNA polymerase enzymes, generating messenger ribonucleotides (mRNA) that are post-transcriptionally modified and exported to the cytoplasm through the combined work of host and viral factors. These viral mRNA b
Externí odkaz:
https://doaj.org/article/f91a4f378cd64bcdb39dc76c1cf6b234
Publikováno v:
Proceedings, Vol 50, Iss 1, p 116 (2020)
Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure the proper folding, post-translational modification and trafficking of secreted and transmembrane viral prote
Externí odkaz:
https://doaj.org/article/3123756e755c4d168d39fb3648079c97
Publikováno v:
Journal of Virology. 96
Kaposi's sarcoma-associated herpesvirus (KSHV) is the cause of several human cancers, including the endothelial cell (EC) malignancy, Kaposi's sarcoma. Unique KSHV genes absent from other human herpesvirus genomes, the "K-genes," are important for KS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505343910203b05968d7862b5ae03840
https://doi.org/10.1128/jvi.01560-21
https://doi.org/10.1128/jvi.01560-21
Autor:
Arun Raturi, Jailal Ablack, Ping Wee, Prakash Bhandari, Douglas W. Brown, Maryam Hejazi, Nichole McMullen, Liliya Grin, Hector Vega, Henry Garcia, Natasha Govindasamy, Jitendra Kumar, Paola Solis Ares, Chandra McAllister, Katia Carmine-Simmen, Perrin H. Beatty, Adam Nelson, Eric S. Pringle, Thornton Thompson, Manoj Parmar, Jennifer Gyoba, Hong Jiang, Brent Johnston, Craig McCormick, Mary Foley, Magen Ellen Francis, Brian Abel, Alyson Kelvin, Roy Duncan, John D. Lewis
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8168da1836746a902d7703aaea5ed4
https://doi.org/10.2139/ssrn.4241174
https://doi.org/10.2139/ssrn.4241174
Autor:
Andrea L.-A. Monjo, Eric S. Pringle, Mackenzie Thornbury, Brett A. Duguay, Susan M. A. Monro, Marc Hetu, Danika Knight, Colin G. Cameron, Sherri A. McFarland, Craig McCormick
Publikováno v:
Viruses, Vol 10, Iss 10, p 532 (2018)
Herpes simplex virus (HSV) infections can be treated with direct acting antivirals like acyclovir and foscarnet, but long-term use can lead to drug resistance, which motivates research into broadly-acting antivirals that can provide a greater genetic
Externí odkaz:
https://doaj.org/article/10cc3dc6be2d472ab388f2886e5f85df
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the cause of several human cancers including the endothelial cell (EC) malignancy, Kaposi’s sarcoma. Unique KSHV genes absent from other human herpesvirus genomes, the “K-genes”, are important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ffcc8077ac9737131adfcbded5ad0f9
https://doi.org/10.1101/2021.06.11.448153
https://doi.org/10.1101/2021.06.11.448153
Autor:
Michel Roberge, Denys A. Khaperskyy, Mariel Kleer, Brett A. Duguay, Patrick D Slaine, Craig McCormick, Aruna D. Balgi, Eric S. Pringle, Shan Ying, Eileigh Kadijk
Publikováno v:
Journal of Virology
Secreted and transmembrane proteins are synthesized in the endoplasmic reticulum (ER), where they are folded and modified prior to transport. Many viruses rely on the ER for the synthesis and processing of viral glycoproteins that will ultimately be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e4922e44f95b37cc6bb409a439778b
https://pubmed.ncbi.nlm.nih.gov/33762409
https://pubmed.ncbi.nlm.nih.gov/33762409