Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Eric S. Mullins"'
Autor:
Sherry Thornton, Harini Raghu, Carolina Cruz, Malinda D. Frederick, Joseph S. Palumbo, Eric S. Mullins, Kasper Almholt, Pernille A. Usher, Matthew J. Flick
Publikováno v:
Blood Advances, Vol 1, Iss 9, Pp 545-556 (2017)
Abstract: The plasminogen activation (PA) system has been implicated in driving inflammatory arthritis, but the precise contribution of PA system components to arthritis pathogenesis remains poorly defined. Here, the role of urokinase plasminogen act
Externí odkaz:
https://doaj.org/article/7797de5dcaab4aa4b35704c191a8fca5
Autor:
Matthew J. Flick, Stephen F. Konieczny, Edith M. Janssen, Bennett D. Elzey, Eric S. Mullins, Joseph S. Palumbo, Alexey S. Revenko, Brett P. Monia, Erin N. Paul, Nadia A. Lanman, Patrick G. Schweickert, Amanda Stang, Yi Yang
Table of differentially expressed genes from RNA-seq analysis of in vitro stimulation of KPC2 cells with and without thrombin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209398d50130dd58fcb43f11e1a521b1
https://doi.org/10.1158/0008-5472.22421115.v1
https://doi.org/10.1158/0008-5472.22421115.v1
Autor:
Joseph S. Palumbo, Brett Monia, Alexey Revenko, David P. Witte, Maureen Shaw, Eric S. Mullins, Eleana Harmel-Laws, Kris A. Steinbrecher, Matthew J. Flick, Keith Kombrinck, Leah Rosenfeldt, Whitney Miller, Brian Turpin
PDF file - 1869KB, Modest ASO-mediated decrease in circulating prothrombin does not significantly affect mucosal injury, inflammatory cell accumulation or local inflammatory cytokine production following DSS challenge (S1). Resolution of inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d04c9fd2aa970a0580c6314a07c8d57
https://doi.org/10.1158/0008-5472.22399734
https://doi.org/10.1158/0008-5472.22399734
Autor:
Shilpa Jain, Ayesha Zia, Margaret V. Ragni, Jennifer E. Dietrich, Peter A. Kouides, Robert F. Sidonio, Charles G. Minard, Eric S. Mullins, Gabe Haller, Allison P. Wheeler, Christina A. Gurnett, Sarah H. O'Brien, Lakshmi Srivaths, Brooke Sadler, Mukta Sharma, Roshni Kulkarni, Jorge Di Paola
Publikováno v:
Blood Advances
Key Points HMB is associated with rare and common variants in genes related to anemias and bleeding disorders.These are the first exome-sequencing results from patients with HMB, as well as their comparison with control exomes.
Visual Abstract
Visual Abstract
Autor:
Maria E Carter Febres, Matthew E Fenchel, Jennifer Pomales, Cristina Tarango, Eric S. Mullins
Publikováno v:
Blood. 140:5593-5594
Autor:
Amy D. Shapiro, B. Gangadharan, J. Bowen, Christoph Male, Helmut Schweiger, C. J. Hofbauer, Verena Berg, Elena Santagostino, Michael Recht, Margaret V. Ragni, Janice M. Staber, Deborah L Brown, Jenny Klintman, Shannon L. Meeks, Birgit M. Reipert, Karin Fijnvandraat, Hassan M. Yaish, Jan Blatny, Catherine E. McGuinn, Eric S. Mullins, Vlad C. Radulescu
Publikováno v:
Blood Adv
Blood advances, 4(22), 5785-5796. American Society of Hematology
Blood advances, 4(22), 5785-5796. American Society of Hematology
Preventing factor VIII (FVIII) inhibitors following replacement therapies with FVIII products in patients with hemophilia A remains an unmet medical need. Better understanding of the early events of evolving FVIII inhibitors is essential for risk ide
Autor:
Zahra J. Gallagher, Maureen A. Shaw, Eric S. Mullins, E. Johan Foster, Neil Ayres, Terence L. Kirley, Sara Fleetwood
Publikováno v:
Biomacromolecules. 21:1103-1111
This study analyzes and evaluates the use of cellulose nanocrystals (CNCs), stiff nanosized natural materials that have been modified to mimic heparin. These CNCs are simple polysaccharides with a similar backbone structure to heparin, which when mod
Autor:
Brenton J. Francisco, Bal Krishan Sharma, Hannah M. Russell, Leah Rosenfeldt, A. Phillip Owens, Matthew J. Flick, Eric S. Mullins, Joseph Palumbo
Publikováno v:
Blood advances. 6(14)
Autor:
Molly W. Shaw, Niki M. Moutsopoulos, Andrew Gary Lum, Eric S. Mullins, Collin Tran, Zhen Gao, Matthew J. Flick, Lakmali Munasinghage Silva, Thomas H. Bugge
Publikováno v:
Blood
Efficient migration of macrophages to sites of inflammation requires cell surface–bound plasmin(ogen). Here, we investigated the mechanisms underlying the deficits of plasmin(ogen)-mediated macrophage migration in 2 models: murine thioglycollate-in
Autor:
Edith M. Janssen, Erin N. Paul, Joseph S. Palumbo, Eric S. Mullins, Patrick G. Schweickert, Matthew J. Flick, Amanda Stang, Stephen F. Konieczny, Nadia A. Lanman, Brett P. Monia, Alexey S. Revenko, Bennett D. Elzey, Yi Yang
Publikováno v:
Cancer Research. 79:3417-3430
Pancreatic ductal adenocarcinoma (PDAC) is associated with robust activity of the coagulation system. To determine mechanisms by which clotting factors influence PDAC tumor progression, we generated and characterized C57Bl/6-derived KPC (KRasG12D, TR