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pro vyhledávání: '"Eric Romeo"'
Autor:
Kaleen Konrad Childers, J. Patrick Rogers, Eric Romeo, Andrew M. Haidle, Michelle R. Machacek
Publikováno v:
Tetrahedron Letters. 54:2506-2510
A novel multi-component reaction has been developed for the synthesis of fully substituted 5-amino-4-carboxamidthiazoles. Condensation of an aldehyde with commercially available 2-amino-2-cyanoacetamide in the presence of elemental sulfur and base af
Autor:
Michelle R. Machacek, Eric Romeo, Kaleen Konrad Childers, J. Patrick Rogers, Andrew M. Haidle
Publikováno v:
ChemInform. 44
Various target compounds, intermediates in the preparation of pharmacologically active substances, are directly obtained by base-promoted condensation of 2-amido-2-cyanoacetamide (I) with a variety of aldehydes in the presence of elemental sulfur.