Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Eric Rhéaume"'
Autor:
Kashif Khan, Bin Yu, Jean-Claude Tardif, Eric Rhéaume, Hamood Al-Kindi, Sabin Filimon, Cristina Pop, Jacques Genest, Renzo Cecere, Adel Schwertani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionThe progression of coronary atherosclerosis is an active and regulated process. The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this sy
Externí odkaz:
https://doaj.org/article/3516f3d5a42545f4bc438d04d76fcab4
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Obstructive sleep apnea (OSA) is linked to an accelerated risk of cardiovascular disease (CVD). Some key CVD risk factors are present in patients suffering from OSA such as hypertension, inflammation, oxidative stress, and dyslipi
Externí odkaz:
https://doaj.org/article/e49c9d876f4e4b2284ab3a379d123e26
Autor:
Mathieu R. Brodeur, David Rhainds, Daniel Charpentier, Marie Boulé, Téodora Mihalache-Avram, Mélanie Mecteau, Geneviève Brand, Valérie Pedneault-Gagnon, Annik Fortier, Eric J. Niesor, Eric Rhéaume, Cyrille Maugeais, Jean-Claude Tardif
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 1, Pp 100316- (2023)
The large HDL particles generated by administration of cholesteryl ester transfer protein inhibitors (CETPi) remain poorly characterized, despite their potential importance in the routing of cholesterol to the liver for excretion, which is the last s
Externí odkaz:
https://doaj.org/article/f4c2963532d24b62b4094a8ce7f0e3c8
Autor:
François Roubille, Nolwenn Merlet, David Busseuil, Marine Ferron, Yanfen Shi, Teodora Mihalache-Avram, Mélanie Mecteau, Geneviève Brand, Daniel Rivas, Mariève Cossette, Marie-Claude Guertin, Eric Rhéaume, Jean-Claude Tardif
Publikováno v:
Atherosclerosis Plus, Vol 45, Iss , Pp 1-9 (2021)
Background and aims: The anti-inflammatory agent colchicine is gaining interest as a treatment for coronary artery disease. However, the effects of colchicine in atherosclerotic animal models are mostly unknown. This study aimed to evaluate colchicin
Externí odkaz:
https://doaj.org/article/4f77011ad4b64b2595504fd26a40faa1
Autor:
Eric J Niesor, Guy Boivin, Eric Rhéaume, Rong Shi, Véronique Lavoie, Nathalie Goyette, Marie-Eve Picard, Anne Perez, Fouzia Laghrissi-Thode, Jean-Claude Tardif
Publikováno v:
ACS Omega, Vol 6, Iss 25, Pp 16584-16591 (2021)
Externí odkaz:
https://doaj.org/article/8f9ee455f48b44fab8b1e496014f92bc
Autor:
Isabel Gamache, Marc-André Legault, Jean-Christophe Grenier, Rocio Sanchez, Eric Rhéaume, Samira Asgari, Amina Barhdadi, Yassamin Feroz Zada, Holly Trochet, Yang Luo, Leonid Lecca, Megan Murray, Soumya Raychaudhuri, Jean-Claude Tardif, Marie-Pierre Dubé, Julie Hussin
Publikováno v:
eLife, Vol 10 (2021)
Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 (ADCY9) gene and clinical responses to the cholesteryl ester transfer protein (CETP) modulator dalcetrapib, however, the mechanism behind this interac
Externí odkaz:
https://doaj.org/article/1eb82435960b4dda9cb9c0f636c44f60
Autor:
Jocelyn Dupuis, Martin G Sirois, Eric Rhéaume, Quang T Nguyen, Marie-Élaine Clavet-Lanthier, Genevieve Brand, Teodora Mihalache-Avram, Gabriel Théberge-Julien, Daniel Charpentier, David Rhainds, Paul-Eduard Neagoe, Jean-Claude Tardif
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242318 (2020)
The acute respiratory distress syndrome (ARDS) is characterized by intense dysregulated inflammation leading to acute lung injury (ALI) and respiratory failure. There are no effective pharmacologic therapies for ARDS. Colchicine is a low-cost, widely
Externí odkaz:
https://doaj.org/article/2b36482340434f8f93bcc91a56badd79
Autor:
Mathieu R. Brodeur, David Rhainds, Daniel Charpentier, Teodora Mihalache-Avram, Mélanie Mecteau, Geneviève Brand, Evelyne Chaput, Anne Perez, Eric J. Niesor, Eric Rhéaume, Cyrille Maugeais, Jean-Claude Tardif
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 7, Pp 1282-1291 (2017)
Inhibition of cholesteryl ester transfer protein (CETP) increases HDL cholesterol (HDL-C) levels. However, the circulating CETP level varies and the impact of its inhibition in species with high CETP levels on HDL structure and function remains poorl
Externí odkaz:
https://doaj.org/article/876df955d54c4367a0e53160b19b2a3f
Autor:
Walid Nachar, Nolwenn Merlet, Foued Maafi, Yanfen Shi, Teodora Mihalache-Avram, Mélanie Mecteau, Marine Ferron, Eric Rhéaume, Jean-Claude Tardif
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220707 (2019)
BackgroundLeft ventricular diastolic dysfunction (LVDD) is present in more than 50% of patients suffering from heart failure. LVDD animal models are limited and its underlying mechanisms remain largely unknown. Aortic valve stenosis (AVS) may cause L
Externí odkaz:
https://doaj.org/article/c4ae1e3364c84f068761ca73fbddad16
Autor:
Cécile Low‐Kam, David Rhainds, Ken Sin Lo, Amina Barhdadi, Marie Boulé, Sonia Alem, Valérie Pedneault‐Gagnon, Eric Rhéaume, Marie‐Pierre Dubé, David Busseuil, Robert A. Hegele, Guillaume Lettre, Jean‐Claude Tardif
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 16 (2018)
Background Macrophage cholesterol efflux to high‐density lipoproteins (HDLs) is the first step of reverse cholesterol transport. The cholesterol efflux capacity (CEC) of HDL particles is a protective risk factor for coronary artery disease independ
Externí odkaz:
https://doaj.org/article/9620ca353a52470d95d9f7fb52bb9e33